Durchbruch bei der Erforschung von Darmerkrankungen: Forscher machen „heiligen Gral“-Entdeckung – Forscher haben einen Haupttreiber von entzündlichen Darmerkrankungen (IBD) und mehreren anderen Immunerkrankungen entdeckt, die die Wirbelsäule, Leber und Arterien beeinträchtigen, und geben damit Millionen von Menschen weltweit neue Hoffnung.
https://www.theguardian.com/society/article/2024/jun/05/bowel-disease-hope-researchers-find-biological-pathway
27 comments
Thank you science.
For someone with UC (Ulcerative colitis) this sounds promising
I hope this leads to medicine that can make a positive difference in people’s (and my) lives sooner rather than later
I wonder how close all this is to something like Lupus
Didn’t see it mentioned specifically, but here’s hoping this helps sufferers of liver disease Primary Schlerosing Cholangitis. Basically your immune system attacks your bile ducts causing inflammation and hardening until your liver goes to hell and you require a transplant. 80% of men with PSC also happen to have ulcerative colitis. I also have T1 diabetes since age 16 and psoriatic issues. I’m one of the lucky ones with slow progression and a relatively normal life, but imagine having a sword of Damocles over your head at all times that could drop and ruin your liver at any moment. My immune system has been trying to kill me for most of my life and eventually it will succeed. I’m happy for anyone whose future benefits from these breakthroughs even if they come after my time.
I have IBD/Crohn’s. This sounds amazing. My wife uses MEK inhibitors at work, I’ve jokingly asked her to hook me up.
And now we can find out who has faulty genes elsewhere causing the inflammation or if it’s this “desert” amplifying the inflammation….or both! What a wonderful day for medicine!
It was Arby’s all along
“now that we have a billable cure, we can start believing women about these immune disorders. “. — your local doctor
As someone who has had crohns for 25 years starting as a kid and now has to get a biologic infusion every 4 weeks that is destroying my veins and gives me crappy side effects and a reduced quality of life, I really hope this breakthrough pans out quickly and provides new and better options for us all. I have been hopeful for a lot of other trials that never amounted to much but here is to hoping this one does. Cheers to the researchers and scientists trying to make our lives better.
UC guy here – please give me this tomorrow
As someone who has already had their bowel removed to this horrible disease I really hope for the future that better treatment is available
Yes, more science for prevention! Not only cures. Yaaaaaascience
Well the good news, they seem both very confident in the treatment and their ability to bring it to market in less than 5 years.
Unfortunately for Americans it will likely cost $10,000 a pill while the rest of the world gets it for $25 a month.
dammit i already lost my colon
r/ulcerativecolitis
Welp there’s go one of my most trusty *get out of work free* cards.
I suffer from Crohns. On my worst days, it feels like I’ve been poisoned and my insides are melting. On my best days, I’m only slightly fatigued.
I’m excited but cautious about this. I’d like to know what adverse effects may come from it as a result. I took Accutane as a teenager and that messed me up bad, possibly causing the Crohns in the first place as there have been suspected links. Learned my lesson after that.
Hail Science!
As someone with Crohn’s this is good news. Now all I gotta worry about is not getting louie body disease my grandfather had or dementia my grandmother had.
It’s interesting that they are looking at the effects related ro other autoimmune diseases like ankylosing spondylitis. Gives me a bit of hope that I can one day stop a weekly injection just to be able to sleep.
Oh man I have AS I really hope this gets to market
Let’s be honest, they have f-up the food so bad in the US, that’s why we have all these disorders that we have never heard about. But you know what? They have a pill for whatever you got lol
Great news. Had the j-pouch surgery in 2001 due to UC so too late for me but I always have a fear of my kids getting it.
But only affordable outside the US
This is awesome. Science is our friend, we need to embrace it and embrace those that dedicate their lives to making our world better.
Nice. I was just discharged from the hospital last week after being diagnosed with UC. Bled so much I almost needed a transfusion.