In his speech, Prince William also warned that the pressures of paramedics’ roles could lead to burnout and significant a impact on their mental wellbeing.
He said: “It is vital that you are also there for yourselves and for each other.”
The College of Paramedics, set up in 2001, has more than 20,000 members. Its role is to promote and develop the paramedic profession across the UK.
Before his speech, the prince met conference speakers and paramedics including Ed Griffiths, an old colleague from RAF Valley.
Mr Griffiths was a winchman on rescue missions with the prince, before joining HM Coastguard as a winch-paramedic.
He said later: “I worked two years with him, I had a great time.
“It was a pleasure, honour and privilege to serve with him and to have life experiences I wouldn’t have got, had I not worked with him.”