Aguilera F, Méndez J, Pásaro E, Laffon B. Review on the effects of exposure to spilled oils on human health. J Appl Toxicol. 2010;30(4):291–301.
International Tanker Owners Pollution Federation Limited. Oil tanker spill statistics 2019. 2020 [cited 2020 Nov 24]. Available from: https://www.itopf.org/fileadmin/data/Documents/Company_Lit/Oil_Spill_Stats_brochure_2020_for_web.pdf
Amin MM, Rafiei N, Poursafa P, Ebrahimpour K, Mozafarian N, Shoshtari-Yeganeh B, et al. Association of benzene exposure with insulin resistance, SOD, and MDA as markers of oxidative stress in children and adolescents. Environ Sci Pollut Res. 2018;25(34):34046–52.
Cakmak S, Cole C, Hebbern C, Andrade J, Dales R. Associations between blood volatile organic compounds, and changes in hematologic and biochemical profiles, in a population-based study. Environ Int. 2020;145:106121.
Choi YH, Kim JH, Lee BE, Hong YC. Urinary benzene metabolite and insulin resistance in elderly adults. Sci Total Environ. 2014;482–483:260–8.
Jardel HV, Engel LS, Lawrence KG, Stewart PA, Stenzel MR, Curry MD, et al. The association between oil spill cleanup-related total hydrocarbon exposure and diabetes. Environ Res. 2022;113591.
Lee I, Park H, Kim MJ, Kim S, Choi S, Park J, et al. Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds is associated with a risk of obesity and diabetes mellitus among Korean adults: Korean National environmental health survey (KoNEHS) 2015–2017. Int J Hyg Environ Health. 2022;240:113886.
Won YL, Ko Y, Heo KH, Ko KS, Lee MY, Kim KW. The effects of long-term, low-level exposure to monocyclic aromatic hydrocarbons on worker’s insulin resistance. Saf Health Work. 2011;2(4):365–74.
Yu L, Liu W, Zhou M, Yang S, Tan Q, Fan L, et al. Long-term effect of styrene and ethylbenzene exposure on fasting plasma glucose: a gene-environment interaction study. J Hazard Mater. 2023;452:131346.
American Diabetes Association. Standards of medical care in diabetes—2019 abridged for primary care providers. Clin Diabetes. 2019;37(1):11–34.
American Diabetes Association. International expert committee report on the role of the A1C assay in the diagnosis of diabetes. Diabetes Care. 2009;32(7):1327–34.
Nathan DM, Turgeon H, Regan S. Relationship between glycated haemoglobin levels and mean glucose levels over time. Diabetologia. 2007;50(11):2239–44.
Sherwani SI, Khan HA, Ekhzaimy A, Masood A, Sakharkar MK. Significance of HbA1c test in diagnosis and prognosis of diabetic patients. Biomark Insights. 2016;11:BMI.S38440.
American Diabetes Association. Classification and diagnosis of diabetes: standards of medical care in diabetes-2018. Diabetes Care. 2018;41(Supplement 1):S13–27.
Beckles GL, Chou CF. Disparities in the prevalence of diagnosed diabetes -United States, 1999–2002 and 2011–2014. MMWR Morb Mortal Wkly Rep. 2016;65(45):1265–9.
Centers for Disease Control. Natl Diabetes Stat Rep. 2017;2017:20.
Kirk JK, D’Agostino RB, Bell RA, Passmore LV, Bonds DE, Karter AJ, et al. Disparities in HbA1c levels between African-American and non-Hispanic white adults with diabetes: a meta-analysis. Diabetes Care. 2006;29(9):2130–6.
Merkin SS, Karlamangla A, Roux AD, Shrager S, Watson K, Seeman T. Race/ethnicity, neighborhood socioeconomic status and cardio-metabolic risk. SSM – Popul Health. 2020;11:100634.
Beckie TM. A systematic review of allostatic load, health, and health disparities. Biol Res Nurs. 2012;14(4):311–46.
Miller HN, LaFave S, Marineau L, Stephens J, Thorpe RJ. The impact of discrimination on allostatic load in adults: an integrative review of literature. J Psychosom Res. 2021;146:110434.
Fletcher B, Gulanick M, Lamendola C. Risk factors for type 2 diabetes mellitus. J Cardiovasc Nurs. 2002;16(2):17–23.
Reddy CM, Arey JS, Seewald JS, Sylva SP, Lemkau KL, Nelson RK, et al. Composition and fate of gas and oil released to the water column during the deepwater horizon oil spill. Proc Natl Acad Sci. 2012;109(50):20229–34.
Dokken BB, Saengsirisuwan V, Kim JS, Teachey MK, Henriksen EJ. Oxidative stress-induced insulin resistance in rat skeletal muscle: role of glycogen synthase kinase-3. Am J Physiol-Endocrinol Metab. 2008;294(3):E615–21.
Gardner CD, Eguchi S, Reynolds CM, Eguchi K, Frank GD, Motley ED. Hydrogen peroxide inhibits insulin signaling in vascular smooth muscle cells. Exp Biol Med. 2003;228(7):836–42.
Gerber PA, Rutter GA. The role of oxidative stress and hypoxia in pancreatic beta-cell dysfunction in diabetes mellitus. Antioxid Redox Signal. 2017;26(10):501–18.
Sakuraba H, Mizukami H, Yagihashi N, Wada R, Hanyu C, Yagihashi S. Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese type II diabetic patients. Diabetologia. 2002;45(1):85–96.
Liu YZ, Roy-Engel AM, Baddoo MC, Flemington EK, Wang G, Wang H. The impact of oil spill to lung health-Insights from an RNA-seq study of human airway epithelial cells. Gene. 2016;578(1):38–51.
Zelko IN, Dassanayaka S, Malovichko MV, Howard CM, Garrett LF, Uchida S, et al. Chronic benzene exposure aggravates pressure overload-induced cardiac dysfunction. Toxicol Sci. 2022;185(1):64–76.
Mögel I, Baumann S, Böhme A, Kohajda T, von Bergen M, Simon JC, et al. The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation. Toxicology. 2011;289(1):28–37.
Zhang M, Wang Y, Wang X, Liu J, Zhang J, Gu Q. Roles of oxidative stress, apoptosis, and Heme oxygenase-1 in ethylbenzene-induced renal toxicity in NRK-52E cells. Toxicol Ind Health. 2016;32(12):1952–60.
Vestergaard S, Loft S, Møller P. Role of inducible nitrogen oxide synthase in benzene-induced oxidative DNA damage in the bone marrow of mice. Free Radic Biol Med. 2002;32(5):481–4.
Uzma N, Kumar BS, Hazari MAH. Exposure to benzene induces oxidative stress, alters the immune response and expression of p53 in gasoline filling workers. Am J Ind Med. 2010;53(12):1264–70.
Salimi A, Talatappe BS, Pourahmad J. Xylene induces oxidative stress and mitochondria damage in isolated human lymphocytes. Toxicol Res. 2017;33(3):233–8.
Moro AM, Brucker N, Charão M, Bulcão R, Freitas F, Baierle M, et al. Evaluation of genotoxicity and oxidative damage in painters exposed to low levels of toluene. Mutat Res Toxicol Environ Mutagen. 2012;746(1):42–8.
Midorikawa K, Uchida T, Okamoto Y, Toda C, Sakai Y, Ueda K, et al. Metabolic activation of carcinogenic ethylbenzene leads to oxidative DNA damage. Chem Biol Interact. 2004;150(3):271–81.
Lagorio S, Tagesson C, Forastiere F, Iavarone I, Axelson O, Carere A. Exposure to benzene and urinary concentrations of 8-hydroxydeoxyguanosine, a biological marker of oxidative damage to DNA. Occup Environ Med. 1994;51(11):739–43.
Kim JH, Moon JY, Park EY, Lee KH, Hong YC. Changes in oxidative stress biomarker and gene expression levels in workers exposed to volatile organic compounds. Ind Health. 2011;49(1):8–14.
Costa-Amaral IC, Carvalho LVB, Santos MVC, Valente D, Pereira AC, Figueiredo VO et al. Environmental assessment and evaluation of oxidative stress and genotoxicity biomarkers related to chronic occupational exposure to benzene. Int J Environ Res Public Health. 2019 Jun [cited 2020 Apr 11];16(12). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617122/
Buthbumrung N, Mahidol C, Navasumrit P, Promvijit J, Hunsonti P, Autrup H, et al. Oxidative DNA damage and influence of genetic polymorphisms among urban and rural schoolchildren exposed to benzene. Chem Biol Interact. 2008;172(3):185–94.
Modak MA, Parab PB, Ghaskadbi SS. Pancreatic islets are very poor in rectifying oxidative DNA damage. Pancreas. 2009;38(1):23–9.
Pi J, Bai Y, Zhang Q, Wong V, Floering LM, Daniel K, et al. Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes. 2007;56(7):1783–91.
Pi J, Zhang Q, Fu J, Woods C, Hou Y, Corkey BE, et al. ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. Toxicol Appl Pharmacol. 2010;244(1):77–83.
Cavaliere G, Viggiano E, Trinchese G, De Filippo C, Messina A, Monda V et al. Long feeding high-fat diet induces hypothalamic oxidative stress and inflammation, and prolonged hypothalamic AMPK activation in rat animal model. Front Physiol. 2018 Jul 6 [cited 2020 Jul 9];9. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043859/
Kaneto H, Kawamori D, Matsuoka T, Kajimoto Y, Yamasaki Y. Oxidative stress and pancreatic b-cell dysfunction. Am J Ther. 2005;5.
Kjaergaard M, Nilsson C, Nielsen MO, Grove K, Raun K. Hypothalamic oxidative stress and inflammation, and peripheral glucose homeostasis in Sprague-Dawley rat offspring exposed to maternal and postnatal chocolate and soft drink. Nutr Diabetes. 2018 Jul 19 [cited 2020 Jul 9];8. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053394/
Kovačević S, Nestorov J, Matić G, Elaković I. Chronic stress combined with a Fructose diet reduces hypothalamic insulin signaling and antioxidative defense in female rats. Neuroendocrinology. 2019;108(4):278–90.
Singh MP, Reddy MMKrishna, Mathur N, Saxena DK, Chowdhuri DK. Induction of hsp70, hsp60, hsp83 and hsp26 and oxidative stress markers in benzene, toluene and xylene exposed Drosophila melanogaster: role of ROS generation. Toxicol Appl Pharmacol. 2009;235(2):226–43.
Singh MP, Ravi Ram K, Mishra M, Shrivastava M, Saxena DK, Chowdhuri DK. Effects of co-exposure of benzene, toluene and xylene to drosophila melanogaster: alteration in hsp70, hsp60, hsp83, hsp26, ROS generation and oxidative stress markers. Chemosphere. 2010;79(5):577–87.
Zilaee M, Shirali S. Heat shock proteins and diabetes. Can J Diabetes. 2016;40(6):594–602.
Kwok RK, Engel LS, Miller AK, Blair A, Curry MD, Jackson WB, et al. The GuLF STUDY: a prospective study of persons involved in the Deepwater horizon oil spill response and clean-up. Environ Health Perspect. 2017;125(4):570–8.
Stewart PA, Groth CP, Huynh TB, Gorman Ng M, Pratt GC, Arnold SF, et al. Assessing exposures from the Deepwater horizon oil spill response and clean-up. Ann Work Expo Health. 2022;66(Supplement1):i3–22.
Ramachandran G, Groth CP, Huynh TB, Banerjee S, Stewart PA, Engel LS, et al. Using real-time area VOC measurements to estimate total hydrocarbons exposures to workers involved in the Deepwater horizon oil spill. Ann Work Expo Health. 2022;66(Supplement1):i156–71.
Groth CP, Banerjee S, Ramachandran G, Stewart PA, Sandler DP, Blair A, et al. Methods for the analysis of 26 million VOC area measurements during the Deepwater horizon oil spill clean-up. Ann Work Expo Health. 2022;66(Supplement1):i140–55.
Huynh T, Quick H, Ramachandran G, Banerjee S, Stenzel M, Sandler DP et al. A comparison of the β-Substitution method and a bayesian method for analyzing left-censored data. Ann Occup Hyg. 2015;mev049.
Stenzel MR, Groth CP, Banerjee S, Ramachandran G, Kwok RK, Engel LS, et al. Exposure assessment techniques applied to the highly censored Deepwater horizon Gulf oil spill personal measurements. Ann Work Expo Health. 2022;66(Supplement1):i56–70.
Groth CP, Huynh TB, Banerjee S, Ramachandran G, Stewart PA, Quick H, et al. Linear relationships between total hydrocarbons and benzene, toluene, ethylbenzene, xylene, and n -Hexane during the Deepwater horizon response and clean-up. Ann Work Expo Health. 2022;66(Supplement1):i71–88.
Blake GJ, Pradhan AD, Manson JE, Williams GR, Buring J, Ridker PM, et al. Hemoglobin A1c level and future cardiovascular events among women. Arch Intern Med. 2004;164(7):757.
Pai JK, Cahill LE, Hu FB, Rexrode KM, Manson JE, Rimm EB. Hemoglobin A 1c Is Associated With Increased Risk of Incident Coronary Heart Disease Among Apparently Healthy, Nondiabetic Men and Women. J Am Heart Assoc. 2013 Mar 12 [cited 2020 Oct 1];2(2). Available from: https://www.ahajournals.org/doi/https://doi.org/10.1161/JAHA.112.000077
Peterson S, Smith H, Cochrane S, Reid Q, Kenbata D, Anong W. The Effects of Whole Blood Centrifugation on Hemoglobin A1c Measurement. J Clin Lab Med. 2018 [cited 2020 May 12];3(1). Available from: https://www.sciforschenonline.org/journals/clinical-laboratory-medicine/JCLM-3-118.php
Keil AP, Buckley JP, O’Brien KM, Ferguson KK, Zhao S, White AJ. A quantile-based g-computation approach to addressing the effects of exposure mixtures. Environ Health Perspect. 2020;128(4):047004.
Tennant PWG, Arnold KF, Ellison GTH, Gilthorpe MS. Analyses of ‘change scores’ do not estimate causal effects in observational data. Int J Epidemiol. 2021;dyab050.
Bartlett JW, Seaman SR, White IR, Carpenter JR. Multiple imputation of covariates by fully conditional specification: accommodating the substantive model. Stat Methods Med Res. 2015;24(4):462–87.
White IR, Royston P, Wood AM. Multiple imputation using chained equations: issues and guidance for practice. Stat Med. 2011;30(4):377–99.
Tobin J. Estimation of relationships for limited dependent variables. Econometrica. 1958;26(1):24–36.
Tobin MD, Sheehan NA, Scurrah KJ, Burton PR. Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure. Stat Med. 2005;24(19):2911–35.
Rubin DB. Multiple imputation for nonresponse in surveys. Volume 81. Wiley; 2004. p. 326.
Greenland S, Pearl J, Robins JM. Causal diagrams for epidemiologic research. Epidemiology. 1999;10(1):37–48.
Knighton AJ, Savitz L, Belnap T, Stephenson B, VanDerslice J. Introduction of an area deprivation index measuring patient socioeconomic status in an integrated health system: Implications for population health. eGEMs. 2016 Aug 11 [cited 2020 Sep 16];4(3). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019337/
Singh GK. Area deprivation and widening inequalities in US mortality, 1969–1998. Am J Public Health. 2003;93(7):1137–43.
University of Wisconsin School of Medicine and Public Health. Area Deprivation Index 2015. 2022 [cited 2022 Apr 12]. Available from: https://www.neighborhoodatlas.medicine.wisc.edu/
Perbellini L, Mozzo P, Brugnone F, Zedde A. Physiologicomathematical model for studying human exposure to organic solvents: kinetics of blood/tissue n-hexane concentrations and of 2,5-hexanedione in urine. Br J Ind Med. 1986;43(11):760–8.
Soleimani E. Benzene, toluene, ethylbenzene, and xylene: current analytical techniques and approaches for biological monitoring. Rev Anal Chem. 2020;39(1):168–87.
Carlsson A, Ljungquist E. Exposure to toluene: concentration in subcutaneous adipose tissue. Scand J Work Environ Health. 1982;8(1):56–62.
R Core Team. R: a langage and environment for statistical computing, Vienna. Austria: R Foundation for Statistical Computing; 2022. Available from: https://www.R-project.org/
Wickham H, Averick M, Bryan J, Chang W, McGowan L, François R, et al. Welcome to the tidyverse. J Open Source Softw. 2019;4(43):1686.
van Buuren S, Groothuis-Oudshoorn K. mice: Multivariate Imputation by Chained Equations in R. J Stat Softw. 2011 [cited 2022 Dec 19];45(3). Available from: http://www.jstatsoft.org/v45/i03/
Keil AP. Package qgcomp. 2023 [cited 2024 Apr 29]. Available from: https://cran.r-project.org/web/packages/qgcomp/qgcomp.pdf
van der Wal WM, Geskus RB. ipw: An R Package for Inverse Probability Weighting. J Stat Softw. 2011 [cited 2023 Mar 24];43(13). Available from: http://www.jstatsoft.org/v43/i13/
Kleiber C, Zeileis A. Applied Econometrics with R. New York: Springer-Verlag; 2008. Available from: https://CRAN.R-project.org/package=AER
Bolden AL, Kwiatkowski CF, Colborn T. New look at BTEX: are ambient levels a problem?? Environ Sci Technol. 2015;49(9):5261–76.
Lagarde F, Beausoleil C, Belcher SM, Belzunces LP, Emond C, Guerbet M, et al. Non-monotonic dose-response relationships and endocrine disruptors: a qualitative method of assessment. Environ Health. 2015;14(1):13.
Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR, Lee DH, et al. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev. 2012;33(3):378–455.
Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, et al. EDC-2: the endocrine society’s second scientific statement on endocrine-Disrupting chemicals. Endocr Rev. 2015;36(6):E1–150.
McCaffery JM, Marsland AL, Strohacker K, Muldoon MF, Manuck SB. Factor structure underlying components of allostatic load. Oresic M, editor. PLoS ONE. 2012;7(10):e47246.
Rodriquez EJ, Kim EN, Sumner AE, Nápoles AM, Pérez-Stable EJ. Allostatic load: importance, markers, and score determination in minority and disparity populations. J Urban Health Bull N Y Acad Med. 2019;96(Suppl 1):3–11.
Alvarez CH. Structural racism as an environmental justice issue: a multilevel analysis of the state racism index and environmental health risk from air toxics. J Racial Ethn Health Disparities. 2023;10(1):244–58.
Doiron D, Setton EM, Shairsingh K, Brauer M, Hystad P, Ross NA, et al. Healthy built environment: spatial patterns and relationships of multiple exposures and deprivation in Toronto, Montreal and Vancouver. Environ Int. 2020;143:106003.
Liu J, Clark LP, Bechle MJ, Hajat A, Kim SY, Robinson AL, et al. Disparities in air pollution exposure in the United States by race/ethnicity and income, 1990–2010. Environ Health Perspect. 2021;129(12):127005.
Abplanalp WT, Wickramasinghe NS, Sithu SD, Conklin DJ, Xie Z, Bhatnagar A, et al. Benzene exposure induces insulin resistance in mice. Toxicol Sci. 2019;167(2):426–37.
Hernán MA, Hernández-Díaz S, Robins JM. A structural approach to selection Bias. Epidemiology. 2004;15(5):615–25.
Glymour MM, Weuve J, Berkman LF, Kawachi I, Robins JM. When is baseline adjustment useful in analyses of change? An example with education and cognitive change?. Am J Epidemiol. 2005;162(3):267–78.
Barnett AG, van der Pols JC, Dobson AJ. Regression to the mean: what it is and how to deal with it. Int J Epidemiol. 2005;34(1):215–20.