Several people have been arrested in Melbourne CBD after a police pursuit.

It is understood the arrests were made near Myer on Bourke Street Mall.

A white BMW with smashed windows has been seen parked in the mall, which is only accessible to pedestrians and trams.

Multiple arrested after police chase Melbourne CBDIt is understood the arrests were made near Myer on Bourke Street Mall. (9News)

The Victoria Police helicopter has been seen over the CBD.

A witness told 3AW she earlier saw what appeared to be a white BMW with smashed windows travelling down Punt Road in South Yarra.

There have been no injuries reported.

Bourke Street Mall arrestsThe Victoria Police helicopter has been seen over the CBD. (9News)

Police say there is no ongoing threat to the community.

Two tram routes have been delayed due to the incident.

Police remain at the scene at the busy shopping area.