Thompson, K. A. et al. N-Aryl–linked spirocyclic polymers for membrane separations of complex hydrocarbon mixtures. Science 369, 310–315 (2020).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Jing, L. et al. Carbon intensity of global crude oil refining and mitigation potential. Nat. Clim. Change 10, 526–532 (2020).

Article 
ADS 
CAS 

Google Scholar
 

Vogt, E. T. C. & Weckhuysen, B. M. The refinery of the future. Nature 629, 295–306 (2024).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Gil, H. Method of removing carbon dioxide emissions from in-situ recovery of bitumen and heavy oil. US patent 8,167,960 (2012).

Ward, A. M. et al. Process and installation for the conversion of crude oil into petrochemical products that have improved BTX performance. US patent 10,259,758 (2019).

Brennecke, J. F. & Freeman, B. Reimagining petroleum refining. Science 369, 254–255 (2020).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Seo, H. & Koh, D.-Y. Refining petroleum with membranes. Science 376, 1053–1054 (2022).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Boam, A., Meniconi, A. & Wu, X. Membrane-based processes for selectively fractionating essential oils. US patent 10,954,468 (2021).

Goel, M. & Mittal, C. P. Membrane-based hybrid process for separation of mixtures of organics, solids, and water. US patent 8,500,990 (2013).

Lee, Y. J. et al. Fractionation of complex aromatic hydrocarbon mixtures using membrane cascades hybridized with distillation. Chem. Eng. J. 503, 158170 (2025).

Article 
CAS 

Google Scholar
 

Bruno, N. C. et al. Solution-processable polytriazoles from spirocyclic monomers for membrane-based hydrocarbon separations. Nat. Mater. 22, 1540–1547 (2023).

Article 
CAS 
PubMed 

Google Scholar
 

International Energy Agency (IEA). Oil Market Report – March 2025. https://www.iea.org/reports/oil-market-report-march-2025 (2025).

Pellegrino, J., Brueske, S., Carole, T. & Andres, H. Energy and environmental profile of the U.S. petroleum refining industry. https://doi.org/10.2172/1218665 (2007).

Intergovernmental Panel on Climate Change (IPCC). Fugitive Emissions. In 2019 Refinement to the 2006 IPCC Guidelines for National Greenhouse Gas Inventories, Vol. 2 Energy (eds Buendia, C. et al.) Ch. 4 (IPCC, 2019).

Chisca, S. et al. Polytriazole membranes with ultrathin tunable selective layer for crude oil fractionation. Science 376, 1105–1110 (2022).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Li, S. et al. Hydrophobic polyamide nanofilms provide rapid transport for crude oil separation. Science 377, 1555–1561 (2022).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Ren, Y. et al. Fluorine-rich poly(arylene amine) membranes for the separation of liquid aliphatic compounds. Science 387, 208–214 (2025).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Lee, T. H. et al. Microporous polyimine membranes for efficient separation of liquid hydrocarbon mixtures. Science 388, 839–844 (2025).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

National Academies of Sciences, Engineering, and Medicine. A Research Agenda for Transforming Separation Science (National Academies Press, 2019).

Lee, Y. J. et al. Data-driven predictions of complex organic mixture permeation in polymer membranes. Nat. Commun. 14, 4931 (2023).

Article 
ADS 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Jones, E. et al. The state of desalination and brine production: a global outlook. Sci. Total Environ. 657, 1343–1356 (2019).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Park, H. B. et al. Maximizing the right stuff: the trade-off between membrane permeability and selectivity. Science 356, eaal5075 (2017).

Article 

Google Scholar
 

Marchetti, P. et al. Molecular separation with organic solvent nanofiltration: a critical review. Chem. Rev. 114, 10735–10806 (2014).

Article 
CAS 
PubMed 

Google Scholar
 

Liang, B. et al. Microporous membranes comprising conjugated polymers with rigid backbones enable ultrafast organic-solvent nanofiltration. Nat. Chem. 10, 961–967 (2018).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Huang, T. et al. Molecularly-porous ultrathin membranes for highly selective organic solvent nanofiltration. Nat. Commun. 11, 5882 (2020).

Article 
ADS 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Cook, M. et al. Roll-to-roll dip coating of three different PIMs for organic solvent nanofiltration. J. Membr. Sci. 558, 52–63 (2018).

Article 
CAS 

Google Scholar
 

Liu, C. et al. Regulating the layered stacking of a covalent triazine framework membrane for aromatic/aliphatic separation. Angew. Chem. Int. Ed. 63, e202320137 (2024).

Article 
CAS 

Google Scholar
 

Alhazmi, B. et al. Ultraselective macrocycle membranes for pharmaceutical ingredients separation in organic solvents. Nat. Commun. 15, 7151 (2024).

Article 
ADS 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

He, A. et al. A smart and responsive crystalline porous organic cage membrane with switchable pore apertures for graded molecular sieving. Nat. Mater. 21, 463–470 (2022).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Lee, T. H. et al. Dual-phase microporous polymer nanofilms by interfacial polymerization for ultrafast molecular separation. Sci. Adv. 10, eadp6666 (2024).

Article 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Huber, P., Wallacher, D., Albers, J. & Knorr, K. Quenching of lamellar ordering in an n-alkane embedded in nanopores. Europhys. Lett. 65, 351–357 (2004).

Article 
ADS 
CAS 

Google Scholar
 

Deng, S. et al. Effect of nanopore confinement on the thermal and structural properties of heneicosan. Thermochim. Acta 664, 57–63 (2018).

Article 
CAS 

Google Scholar
 

Wang, X. et al. Phase behaviors of n-octacosane in nanopores: role of pore size and morphology. Thermochim. Acta 690, 178687 (2020).

Article 
CAS 

Google Scholar
 

Wu, H. et al. Large-scale fabrication of flexible EPDM/MXene/PW phase change composites with excellent light-to-thermal conversion efficiency via water-assisted melt blending. Compos. A Appl. Sci. Manuf. 152, 106713 (2022).

Article 
CAS 

Google Scholar
 

Adams, J. J. Asphaltene adsorption, a literature review. Energy Fuels 28, 2831–2856 (2014).

Article 
CAS 

Google Scholar
 

Christenson, H. K. Confinement effects on freezing and melting. J. Phys. Condens. Matter 13, R95–R133 (2001).

Article 
ADS 
CAS 

Google Scholar
 

Alcoutlabi, M. & McKenna, G. B. Effects of confinement on material behaviour at the nanometre size scale. J. Phys. Condens. Matter 17, R461–R524 (2005).

Article 
ADS 
CAS 

Google Scholar
 

Zeinali Danalou, S. et al. From coated to uncoated: scanning electron microscopy corrections to estimate the true surface pore size in nanoporous membranes. ACS Appl. Mater. Interfaces 17, 63804–63816 (2025).

Article 
CAS 
PubMed 

Google Scholar
 

Viswanath, D. S. et al. Viscosity of Liquids: Theory, Estimation, Experiment, and Data (Springer, 2007).

Hansen, C. M. Hansen Solubility Parameters: A User’s Handbook 2nd edn (CRC Press, 2007).

Lee, M. et al. Enhanced energy efficiency and reduced CO2 emissions by hybrid heat integration in dimethyl carbonate production systems. Sep. Purif. Technol. 287, 120598 (2022).

Article 
CAS 

Google Scholar
 

Gary, J. H., Handwerk, J. E., Geddes, D. E. & Kaiser, M. J. Petroleum Refining: Technology and Economics 5th edn (CRC Press, 2007).

Lee, M. et al. Circulation of self-supplied water for significant energy recovery through heat integration. Energy Convers. Manag: X 24, 100740 (2024).

CAS 

Google Scholar
 

Choi, J. et al. Ultrathin organosiloxane membrane for precision organic solvent nanofiltration. Nat. Commun. 15, 2800 (2024).

Article 
ADS 
CAS 
PubMed 
PubMed Central 

Google Scholar
 

Jung, B., Yoon, J. K., Kim, B. & Rhee, H.-W. Effect of crystallization and annealing on polyacrylonitrile membranes for ultrafiltration. J. Membr. Sci. 246, 67–76 (2005).

Article 
CAS 

Google Scholar
 

Yang, C. et al. in Handbook of Oil Spill Science and Technology 93–163 (Wiley, 2015).

Fernandez-Lima, F. A. et al. Petroleum crude oil characterization by IMS-MS and FTICR MS. Anal. Chem. 81, 9941–9947 (2009).

Article 
ADS 
CAS 
PubMed 

Google Scholar
 

Gadalla, M. A. et al. Reducing CO2 emissions and energy consumption of heat-integrated distillation systems. Environ. Sci. Technol. 39, 6860–6870 (2005).

Article 
ADS 
CAS 
PubMed 

Google Scholar