Wissenschaftlern ist es gelungen, die Gene von Hühnern zu verändern, um eine Vogelgrippe-Infektion einzudämmen

by giuliomagnifico

33 comments

  2. Dammit. When I read “Scientists successfully gene-edit chickens…” I thought they were making dinosaurs

  3. Yes yes, genetically modify the food. Make it more profitable.

  4. Using gene technology to fix a problem caused by exorbitant meat production. Anything but to address the root cause.

  5. *GMO!?!* 😱 What ever will we do with the unhealthy chickens?

  8. …Which in turn, will probably cause cancer. But who cares? It will only become evident in a couple of decades.

  9. Shouldn’t they just make a vaccine?? Sounds safer and easier!

  10. This is good news that is also full of potential

    Your family predisposed to heart failure, not anymore

  11. Fantastic! Can we now figure out how to gene-edit humans so 40% of us aren’t susceptible to believing conspiracy theories?

    /s

  12. This article cover photo just made me realize chickens are fucking scary looking

  15. Great! Now we can go back to keeping 8 chickens crammed in a tiny cage stacked on top of each other covered in unbelievable amounts of shit.

  17. Please, please keep a very healthy population of unedited chickens alive, you don’t know what those effects will have years from now.

  18. Me holding up an Iguana: “Behold, I too have a gene-edited chicken that is resistant to bird flu.”

  21. I feel like genetically engineered chicken tonight, like genetically engineered chicken tonight? 🐔

  22. So this will just mean the flue will have to evolve to be stronger to infect chickens, surely that wont have unintented consequences

  23. To all the “Stop playing God!” crowd:

    If God would have fixed his own mistakes, we wouldn’t have to.

  24. Great, now watch the emergence of some hyper-contagious, hyper-virulent strain due to the evolutionary selective pressure caused by this.

  25. What could go wrong?

    Seriously, feel free to speculate for me.

  26. Cross breed chickens for hundreds of years… nobody cares. Say “GMO” and everyone loses their minds.

  27. “Our chicken supply is safe and our future now secured”

  28. I wonder if this could work for bacterial infections too. Could be huge for limiting antibiotic resistance

  29. Humans accessing creator mode is definitely a glitch in the matrix

  30. The other thing scientists did in Israel is genetically modify chickens so gender can always be female.

    However there setup means you rely on the business instead of doing it another way where you don’t have to do that.

    Only do it to so many but not all. So the farmers can still bread and then change gender. I think it’s when exposed to UV light. Also if we combine both modifications then what happens when we do?

    No money in the factory chickens all having to be bought from a factory.

    You would want a gene that can pass down if a farmer so you can change gender when wanted but they don’t want that because then they make nothing more than a round of chickens.

    Also they are brutal to those chickens in the factory making those chicks.

    Watch the video. Animal rights in America be screaming at how they go along a convery belt alive then get slammed along and dumped over as live chickens. Some hatching still and some not hatched while others are already out of the eggs.

    Doing it the pass down method can mean farmers cab still get males when needed specially when they want fresh DNA. Of course farmers having to pay for the chicks can be like we sale you ours to make the difference. Then you genetically modify them for us. But dang it is still a screw over by big corporate.

    That was in Israel.

    Ok so we decided international they don’t want genetics to pass down even when this is human and it means their offspring is going to suffer the same way.

    So ethically it’s so they get to make money on your children growing up to suffer later with them going through the same genetically modified process that makes them tons of money.

    That’s why they will say it is unethical the other way yet they doing something unethical in another way still.

    No money in cure. They get money on return patients. Unethical to allow a future generation to suffer when you could do something about it before they are born.

    Religiously at the time of the end we all start changing ourselves. Re-write. So we are not all doing it right now and this is limited to people suffering for the most part.

    Lulu and Nana and some other unidentified humans exist who are genetically modified who are designer babies. To prevent HIV, the father was HIV positive. However sperm washing without genetically modifying people can allow healthy babies without HIV.

    So CCR5 was modified and this gives them resistance or immunity to HIV. Reduces life span to 72 to 75 years or something and possibly made them more intelligent. The latter parts was side effects.

    Then they may be mosaics they way they did that and they can pass DNA down through the gene pool via natural selection.

  31. Aaaaaand…what happens when the bird flu mutates (as diseases commonly do) and the gene-edited chickens start getting sick from it? Re-edit the chickens again?

  33. Modern problems require modern solutions. It’s not like we can convince people to not eat chickens.

    It will however take a few years until they are ready. According to [this article](https://www.reuters.com/article/us-health-pandemic-chickens-idUSKCN1PG007) the study about the ANP32 gene was published in 2016 and the first chicken was probably produced in 2019. Now it’s 2023 and we need to edit more genes and do more testing to make sure that influenza viruses can’t spread undetected. Also there is clearly an issue with influenza adapting to this change and thus becoming becoming more dangerous to humans.

    [Here](https://phys.org/news/2023-10-gene-edited-chickens-bird-flu.html) is another article from today.

    [Here](https://www.nature.com/articles/s41467-023-41476-3) is the study.

    “*Influenza virus is notorious for its ability to evolve, and we detected a series of different amino acid substitutions in the viral polymerase genes of viruses isolated from the GE chickens that had enabled adaptation of the enzyme to co-opt support from the edited ANP32A protein, and also to utilise otherwise suboptimal ANP32 family members.* ***These mutations unexpectedly allowed the usually host-restricted avian influenza polymerase to use the shorter human ANP32A and B and thus partially adapted the viral polymerase for replication in mammals.*** *Although unintended, this consequence clearly indicates the importance of a robust genome editing strategy and subsequent appraisal that includes challenge with multiple avian influenza genotypes at non-physiological exposure levels to rule out the opportunity for adaptive viral evolution.”*

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