{"id":124202,"date":"2026-07-30T12:16:12","date_gmt":"2026-07-30T12:16:12","guid":{"rendered":"https:\/\/www.europesays.com\/ai\/124202\/"},"modified":"2026-07-30T12:16:12","modified_gmt":"2026-07-30T12:16:12","slug":"agentic-ai-for-scaling-diagnosis-and-care-in-neurodegenerative-disease","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ai\/124202\/","title":{"rendered":"Agentic AI for scaling diagnosis and care in neurodegenerative disease"},"content":{"rendered":"<p class=\"c-article-references__text\" id=\"ref-CR1\">Hebert, L. E., Weuve, J., Scherr, P. A. &amp; Evans, D. A. Alzheimer disease in the United States (2010\u20132050) estimated using the 2010 census. Neurology 80, 1778\u20131783 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1212\/WNL.0b013e31828726f5\" data-track-item_id=\"10.1212\/WNL.0b013e31828726f5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1212%2FWNL.0b013e31828726f5\" aria-label=\"Article reference 1\" data-doi=\"10.1212\/WNL.0b013e31828726f5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=23390181\" aria-label=\"PubMed reference 1\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3719424\" aria-label=\"PubMed Central reference 1\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 1\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Alzheimer%20disease%20in%20the%20United%20States%20%282010%E2%80%932050%29%20estimated%20using%20the%202010%20census&amp;journal=Neurology&amp;doi=10.1212%2FWNL.0b013e31828726f5&amp;volume=80&amp;pages=1778-1783&amp;publication_year=2013&amp;author=Hebert%2CLE&amp;author=Weuve%2CJ&amp;author=Scherr%2CPA&amp;author=Evans%2CDA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR2\">GBD 2016 Neurology Collaborators. Global, regional, and national burden of neurological disorders, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 18, 459\u2013480 (2019).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR3\">Fang, M. et al. Lifetime risk and projected burden of dementia. Nat. Med. <a href=\"https:\/\/doi.org\/10.1038\/s41591-024-03340-9\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1038\/s41591-024-03340-9\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1038\/s41591-024-03340-9<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR4\">Bradford, A., Kunik, M. E., Schulz, P., Williams, S. P. &amp; Singh, H. Missed and delayed diagnosis of dementia in primary care: prevalence and contributing factors. Alzheimer Dis. Assoc. Disord. 23, 306\u2013314 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1097\/WAD.0b013e3181a6bebc\" data-track-item_id=\"10.1097\/WAD.0b013e3181a6bebc\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1097%2FWAD.0b013e3181a6bebc\" aria-label=\"Article reference 4\" data-doi=\"10.1097\/WAD.0b013e3181a6bebc\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=19568149\" aria-label=\"PubMed reference 4\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2787842\" aria-label=\"PubMed Central reference 4\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 4\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Missed%20and%20delayed%20diagnosis%20of%20dementia%20in%20primary%20care%3A%20prevalence%20and%20contributing%20factors&amp;journal=Alzheimer%20Dis.%20Assoc.%20Disord.&amp;doi=10.1097%2FWAD.0b013e3181a6bebc&amp;volume=23&amp;pages=306-314&amp;publication_year=2009&amp;author=Bradford%2CA&amp;author=Kunik%2CME&amp;author=Schulz%2CP&amp;author=Williams%2CSP&amp;author=Singh%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR5\">Kotagal, V. et al. Factors associated with cognitive evaluations in the United States. Neurology 84, 64\u201371 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1212\/WNL.0000000000001096\" data-track-item_id=\"10.1212\/WNL.0000000000001096\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1212%2FWNL.0000000000001096\" aria-label=\"Article reference 5\" data-doi=\"10.1212\/WNL.0000000000001096\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25428689\" aria-label=\"PubMed reference 5\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 5\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Factors%20associated%20with%20cognitive%20evaluations%20in%20the%20United%20States&amp;journal=Neurology&amp;doi=10.1212%2FWNL.0000000000001096&amp;volume=84&amp;pages=64-71&amp;publication_year=2015&amp;author=Kotagal%2CV\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR6\">Babulal, G. M. et al. Perspectives on ethnic and racial disparities in Alzheimer\u2019s disease and related dementias: update and areas of immediate need. Alzheimers Dement. 15, 292\u2013312 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.jalz.2018.09.009\" data-track-item_id=\"10.1016\/j.jalz.2018.09.009\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.jalz.2018.09.009\" aria-label=\"Article reference 6\" data-doi=\"10.1016\/j.jalz.2018.09.009\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30555031\" aria-label=\"PubMed reference 6\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 6\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Perspectives%20on%20ethnic%20and%20racial%20disparities%20in%20Alzheimer%E2%80%99s%20disease%20and%20related%20dementias%3A%20update%20and%20areas%20of%20immediate%20need&amp;journal=Alzheimers%20Dement.&amp;doi=10.1016%2Fj.jalz.2018.09.009&amp;volume=15&amp;pages=292-312&amp;publication_year=2019&amp;author=Babulal%2CGM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR7\">Boustani, M. et al. Implementing a screening and diagnosis program for dementia in primary care. J. Gen. Intern. Med. 20, 572\u2013577 (2005).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s11606-005-0103-7\" data-track-item_id=\"10.1007\/s11606-005-0103-7\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s11606-005-0103-7\" aria-label=\"Article reference 7\" data-doi=\"10.1007\/s11606-005-0103-7\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16050849\" aria-label=\"PubMed reference 7\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1490164\" aria-label=\"PubMed Central reference 7\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 7\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Implementing%20a%20screening%20and%20diagnosis%20program%20for%20dementia%20in%20primary%20care&amp;journal=J.%20Gen.%20Intern.%20Med.&amp;doi=10.1007%2Fs11606-005-0103-7&amp;volume=20&amp;pages=572-577&amp;publication_year=2005&amp;author=Boustani%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR8\">Bernstein, A. et al. Primary care provider attitudes and practices evaluating and managing patients with neurocognitive disorders. J. Gen. Intern. Med. 34, 1691\u20131692 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s11606-019-05013-7\" data-track-item_id=\"10.1007\/s11606-019-05013-7\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s11606-019-05013-7\" aria-label=\"Article reference 8\" data-doi=\"10.1007\/s11606-019-05013-7\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31044411\" aria-label=\"PubMed reference 8\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6712190\" aria-label=\"PubMed Central reference 8\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 8\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Primary%20care%20provider%20attitudes%20and%20practices%20evaluating%20and%20managing%20patients%20with%20neurocognitive%20disorders&amp;journal=J.%20Gen.%20Intern.%20Med.&amp;doi=10.1007%2Fs11606-019-05013-7&amp;volume=34&amp;pages=1691-1692&amp;publication_year=2019&amp;author=Bernstein%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR9\">Majersik, J. J. et al. A shortage of neurologists \u2013 we must act now: a report from the AAN 2019 Transforming Leaders Program. Neurology 96, 1122\u20131134 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1212\/WNL.0000000000012111\" data-track-item_id=\"10.1212\/WNL.0000000000012111\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1212%2FWNL.0000000000012111\" aria-label=\"Article reference 9\" data-doi=\"10.1212\/WNL.0000000000012111\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33931527\" aria-label=\"PubMed reference 9\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 9\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20shortage%20of%20neurologists%20%E2%80%93%20we%20must%20act%20now%3A%20a%20report%20from%20the%20AAN%202019%20Transforming%20Leaders%20Program&amp;journal=Neurology&amp;doi=10.1212%2FWNL.0000000000012111&amp;volume=96&amp;pages=1122-1134&amp;publication_year=2021&amp;author=Majersik%2CJJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR10\">Satiani, A., Niedermier, J., Satiani, B. &amp; Svendsen, D. P. Projected workforce of psychiatrists in the United States: a population analysis. Psychiatr. Serv. 69, 710\u2013713 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1176\/appi.ps.201700344\" data-track-item_id=\"10.1176\/appi.ps.201700344\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1176%2Fappi.ps.201700344\" aria-label=\"Article reference 10\" data-doi=\"10.1176\/appi.ps.201700344\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29540118\" aria-label=\"PubMed reference 10\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 10\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Projected%20workforce%20of%20psychiatrists%20in%20the%20United%20States%3A%20a%20population%20analysis&amp;journal=Psychiatr.%20Serv.&amp;doi=10.1176%2Fappi.ps.201700344&amp;volume=69&amp;pages=710-713&amp;publication_year=2018&amp;author=Satiani%2CA&amp;author=Niedermier%2CJ&amp;author=Satiani%2CB&amp;author=Svendsen%2CDP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR11\">Flaherty, E. &amp; Bartels, S. J. Addressing the community-based geriatric healthcare workforce shortage by leveraging the potential of interprofessional teams. J. Am. Geriatr. Soc. 67, S400\u2013S408 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/jgs.15924\" data-track-item_id=\"10.1111\/jgs.15924\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fjgs.15924\" aria-label=\"Article reference 11\" data-doi=\"10.1111\/jgs.15924\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31074849\" aria-label=\"PubMed reference 11\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 11\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Addressing%20the%20community-based%20geriatric%20healthcare%20workforce%20shortage%20by%20leveraging%20the%20potential%20of%20interprofessional%20teams&amp;journal=J.%20Am.%20Geriatr.%20Soc.&amp;doi=10.1111%2Fjgs.15924&amp;volume=67&amp;pages=S400-S408&amp;publication_year=2019&amp;author=Flaherty%2CE&amp;author=Bartels%2CSJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR12\">Liu, J. L. et al. Modeling early detection and geographic variation in health system capacity for Alzheimer\u2019s disease-modifying therapies. RAND Corp. <a href=\"https:\/\/doi.org\/10.7249\/RRA2643-1\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.7249\/RRA2643-1\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.7249\/RRA2643-1<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR13\">van Dyck, C. H. et al. Lecanemab in early Alzheimer\u2019s disease. N. Engl. J. Med. 388, 9\u201321 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1056\/NEJMoa2212948\" data-track-item_id=\"10.1056\/NEJMoa2212948\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1056%2FNEJMoa2212948\" aria-label=\"Article reference 13\" data-doi=\"10.1056\/NEJMoa2212948\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36449413\" aria-label=\"PubMed reference 13\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 13\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Lecanemab%20in%20early%20Alzheimer%E2%80%99s%20disease&amp;journal=N.%20Engl.%20J.%20Med.&amp;doi=10.1056%2FNEJMoa2212948&amp;volume=388&amp;pages=9-21&amp;publication_year=2023&amp;author=Dyck%2CCH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR14\">Sims, J. R. et al. Donanemab in early symptomatic Alzheimer disease: the TRAILBLAZER-ALZ 2 randomized clinical trial. JAMA 330, 512\u2013527 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jama.2023.13239\" data-track-item_id=\"10.1001\/jama.2023.13239\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjama.2023.13239\" aria-label=\"Article reference 14\" data-doi=\"10.1001\/jama.2023.13239\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37459141\" aria-label=\"PubMed reference 14\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10352931\" aria-label=\"PubMed Central reference 14\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 14\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Donanemab%20in%20early%20symptomatic%20Alzheimer%20disease%3A%20the%20TRAILBLAZER-ALZ%202%20randomized%20clinical%20trial&amp;journal=JAMA&amp;doi=10.1001%2Fjama.2023.13239&amp;volume=330&amp;pages=512-527&amp;publication_year=2023&amp;author=Sims%2CJR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR15\">Guiding an Improved Dementia Experience (GUIDE) Model. CMS <a href=\"https:\/\/www.cms.gov\/priorities\/innovation\/innovation-models\/guide\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.cms.gov\/priorities\/innovation\/innovation-models\/guide\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.cms.gov\/priorities\/innovation\/innovation-models\/guide\/<\/a> (accessed 18 April 2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR16\">Singhal, K. et al. Large language models encode clinical knowledge. Nature 620, 172\u2013180 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41586-023-06291-2\" data-track-item_id=\"10.1038\/s41586-023-06291-2\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41586-023-06291-2\" aria-label=\"Article reference 16\" data-doi=\"10.1038\/s41586-023-06291-2\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37438534\" aria-label=\"PubMed reference 16\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10396962\" aria-label=\"PubMed Central reference 16\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 16\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Large%20language%20models%20encode%20clinical%20knowledge&amp;journal=Nature&amp;doi=10.1038%2Fs41586-023-06291-2&amp;volume=620&amp;pages=172-180&amp;publication_year=2023&amp;author=Singhal%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR17\">Singhal, K. et al. Toward expert-level medical question answering with large language models. Nat. Med. <a href=\"https:\/\/doi.org\/10.1038\/s41591-024-03423-7\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1038\/s41591-024-03423-7\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1038\/s41591-024-03423-7<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR18\">Tu, T. et al. Towards generalist biomedical AI. NEJM AI 1, AIoa2300138 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1056\/AIoa2300138\" data-track-item_id=\"10.1056\/AIoa2300138\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1056%2FAIoa2300138\" aria-label=\"Article reference 18\" data-doi=\"10.1056\/AIoa2300138\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 18\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Towards%20generalist%20biomedical%20AI&amp;journal=NEJM%20AI&amp;doi=10.1056%2FAIoa2300138&amp;volume=1&amp;publication_year=2024&amp;author=Tu%2CT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR19\">Tu, T. et al. Towards conversational diagnostic artificial intelligence. Nature <a href=\"https:\/\/doi.org\/10.1038\/s41586-025-08866-7\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1038\/s41586-025-08866-7\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1038\/s41586-025-08866-7<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR20\">Liu X., et al. A generalist medical language model for disease diagnosis assistance. Nat. Med. <a href=\"https:\/\/doi.org\/10.1038\/s41591-024-03416-6\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1038\/s41591-024-03416-6\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1038\/s41591-024-03416-6<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR21\">American Medical Association Center for Digital Health and AI. 2026 Physician Survey on Augmented Intelligence 2026. ama-assn.org <a href=\"http:\/\/www.ama-assn.org\/system\/files\/physician-ai-sentiment-report.pdf\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/www.ama-assn.org\/system\/files\/physician-ai-sentiment-report.pdf\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.ama-assn.org\/system\/files\/physician-ai-sentiment-report.pdf<\/a> (2026).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR22\">Gupta, R. et al. The shift from models to compound AI systems. The Berkeley Artificial Intelligence Research Blog <a href=\"http:\/\/bair.berkeley.edu\/blog\/2024\/02\/18\/compound-ai-systems\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/bair.berkeley.edu\/blog\/2024\/02\/18\/compound-ai-systems\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/bair.berkeley.edu\/blog\/2024\/02\/18\/compound-ai-systems\/<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR23\">Acharya, D. B., Kuppan, K. &amp; Divya, B. Agentic AI: autonomous intelligence for complex goals\u2014a comprehensive survey. IEEE Access 13, 18912\u201318936 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1109\/ACCESS.2025.3532853\" data-track-item_id=\"10.1109\/ACCESS.2025.3532853\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1109%2FACCESS.2025.3532853\" aria-label=\"Article reference 23\" data-doi=\"10.1109\/ACCESS.2025.3532853\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 23\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Agentic%20AI%3A%20autonomous%20intelligence%20for%20complex%20goals%E2%80%94a%20comprehensive%20survey&amp;journal=IEEE%20Access&amp;doi=10.1109%2FACCESS.2025.3532853&amp;volume=13&amp;pages=18912-18936&amp;publication_year=2025&amp;author=Acharya%2CDB&amp;author=Kuppan%2CK&amp;author=Divya%2CB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR24\">For trustworthy AI, keep the human in the loop. Nat Med. 31, 3207 (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR25\">Sheehy, L. et al. Development and initial testing of an artificial intelligence-based virtual reality companion for people living with dementia in long-term care. J. Clin. Med. 13, 5574 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.3390\/jcm13185574\" data-track-item_id=\"10.3390\/jcm13185574\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.3390%2Fjcm13185574\" aria-label=\"Article reference 25\" data-doi=\"10.3390\/jcm13185574\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39337060\" aria-label=\"PubMed reference 25\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11432461\" aria-label=\"PubMed Central reference 25\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 25\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Development%20and%20initial%20testing%20of%20an%20artificial%20intelligence-based%20virtual%20reality%20companion%20for%20people%20living%20with%20dementia%20in%20long-term%20care&amp;journal=J.%20Clin.%20Med.&amp;doi=10.3390%2Fjcm13185574&amp;volume=13&amp;publication_year=2024&amp;author=Sheehy%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR26\">Ray, M. et al. Evaluating a large language model in translating patient instructions to spanish using a standardized framework. JAMA Pediatr. 179, 1026\u20131033 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jamapediatrics.2025.1729\" data-track-item_id=\"10.1001\/jamapediatrics.2025.1729\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjamapediatrics.2025.1729\" aria-label=\"Article reference 26\" data-doi=\"10.1001\/jamapediatrics.2025.1729\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40622720\" aria-label=\"PubMed reference 26\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12235533\" aria-label=\"PubMed Central reference 26\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 26\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evaluating%20a%20large%20language%20model%20in%20translating%20patient%20instructions%20to%20spanish%20using%20a%20standardized%20framework&amp;journal=JAMA%20Pediatr.&amp;doi=10.1001%2Fjamapediatrics.2025.1729&amp;volume=179&amp;pages=1026-1033&amp;publication_year=2025&amp;author=Ray%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR27\">Tong, L. et al. Telemedicine and health disparities: Association between patient characteristics and telemedicine, in-person, telephone and message-based care during the COVID-19 pandemic. IPEM Transl. 3, 100010 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.ipemt.2022.100010\" data-track-item_id=\"10.1016\/j.ipemt.2022.100010\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.ipemt.2022.100010\" aria-label=\"Article reference 27\" data-doi=\"10.1016\/j.ipemt.2022.100010\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36340828\" aria-label=\"PubMed reference 27\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9617798\" aria-label=\"PubMed Central reference 27\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 27\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Telemedicine%20and%20health%20disparities%3A%20Association%20between%20patient%20characteristics%20and%20telemedicine%2C%20in-person%2C%20telephone%20and%20message-based%20care%20during%20the%20COVID-19%20pandemic&amp;journal=IPEM%20Transl.&amp;doi=10.1016%2Fj.ipemt.2022.100010&amp;volume=3&amp;publication_year=2022&amp;author=Tong%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR28\">Nota, S. P. F. T., Strooker, J. A. &amp; Ring, D. Differences in response rates between mail, e-mail, and telephone follow-up in hand surgery research. Hand 9, 504\u2013510 (2014).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s11552-014-9618-x\" data-track-item_id=\"10.1007\/s11552-014-9618-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s11552-014-9618-x\" aria-label=\"Article reference 28\" data-doi=\"10.1007\/s11552-014-9618-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25414613\" aria-label=\"PubMed reference 28\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4235909\" aria-label=\"PubMed Central reference 28\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 28\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Differences%20in%20response%20rates%20between%20mail%2C%20e-mail%2C%20and%20telephone%20follow-up%20in%20hand%20surgery%20research&amp;journal=Hand&amp;doi=10.1007%2Fs11552-014-9618-x&amp;volume=9&amp;pages=504-510&amp;publication_year=2014&amp;author=Nota%2CSPFT&amp;author=Strooker%2CJA&amp;author=Ring%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR29\">Pag\u00e1n, V. M., McClung, K. S. &amp; Peden, C. J. An observational study of disparities in telemedicine utilization in primary care patients before and during the COVID-19 pandemic. Telemed. J. E Health 28, 1117\u20131125 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1089\/tmj.2021.0412\" data-track-item_id=\"10.1089\/tmj.2021.0412\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1089%2Ftmj.2021.0412\" aria-label=\"Article reference 29\" data-doi=\"10.1089\/tmj.2021.0412\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34935517\" aria-label=\"PubMed reference 29\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 29\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=An%20observational%20study%20of%20disparities%20in%20telemedicine%20utilization%20in%20primary%20care%20patients%20before%20and%20during%20the%20COVID-19%20pandemic&amp;journal=Telemed.%20J.%20E%20Health&amp;doi=10.1089%2Ftmj.2021.0412&amp;volume=28&amp;pages=1117-1125&amp;publication_year=2022&amp;author=Pag%C3%A1n%2CVM&amp;author=McClung%2CKS&amp;author=Peden%2CCJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR30\">Hinton, L. et al. Practice constraints, behavioral problems, and dementia care: primary care physicians\u2019 perspectives. J. Gen. Intern. Med. 22, 1487\u20131492 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s11606-007-0317-y\" data-track-item_id=\"10.1007\/s11606-007-0317-y\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s11606-007-0317-y\" aria-label=\"Article reference 30\" data-doi=\"10.1007\/s11606-007-0317-y\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=17823840\" aria-label=\"PubMed reference 30\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2219799\" aria-label=\"PubMed Central reference 30\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 30\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Practice%20constraints%2C%20behavioral%20problems%2C%20and%20dementia%20care%3A%20primary%20care%20physicians%E2%80%99%20perspectives&amp;journal=J.%20Gen.%20Intern.%20Med.&amp;doi=10.1007%2Fs11606-007-0317-y&amp;volume=22&amp;pages=1487-1492&amp;publication_year=2007&amp;author=Hinton%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR31\">Qu, Y. &amp; Wang, J. Performance and biases of large language models in public opinion simulation. Humanit. Soc. Sci. Commun. 11, 1\u201313 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1057\/s41599-024-03609-x\" data-track-item_id=\"10.1057\/s41599-024-03609-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1057%2Fs41599-024-03609-x\" aria-label=\"Article reference 31\" data-doi=\"10.1057\/s41599-024-03609-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 31\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Performance%20and%20biases%20of%20large%20language%20models%20in%20public%20opinion%20simulation&amp;journal=Humanit.%20Soc.%20Sci.%20Commun.&amp;doi=10.1057%2Fs41599-024-03609-x&amp;volume=11&amp;pages=1-13&amp;publication_year=2024&amp;author=Qu%2CY&amp;author=Wang%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR32\">Van Veen, D. et al. Adapted large language models can outperform medical experts in clinical text summarization. Nat. Med. 30, 1134\u20131142 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41591-024-02855-5\" data-track-item_id=\"10.1038\/s41591-024-02855-5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41591-024-02855-5\" aria-label=\"Article reference 32\" data-doi=\"10.1038\/s41591-024-02855-5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38413730\" aria-label=\"PubMed reference 32\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11479659\" aria-label=\"PubMed Central reference 32\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 32\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Adapted%20large%20language%20models%20can%20outperform%20medical%20experts%20in%20clinical%20text%20summarization&amp;journal=Nat.%20Med.&amp;doi=10.1038%2Fs41591-024-02855-5&amp;volume=30&amp;pages=1134-1142&amp;publication_year=2024&amp;author=Veen%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR33\">Breithaupt, A. G. et al. Enhancing early detection of cognitive impairment in primary care with the TabCAT-BHA. Alzheimers Dement. 21, e70437 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/alz.70437\" data-track-item_id=\"10.1002\/alz.70437\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Falz.70437\" aria-label=\"Article reference 33\" data-doi=\"10.1002\/alz.70437\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40613257\" aria-label=\"PubMed reference 33\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12231204\" aria-label=\"PubMed Central reference 33\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 33\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Enhancing%20early%20detection%20of%20cognitive%20impairment%20in%20primary%20care%20with%20the%20TabCAT-BHA&amp;journal=Alzheimers%20Dement.&amp;doi=10.1002%2Falz.70437&amp;volume=21&amp;publication_year=2025&amp;author=Breithaupt%2CAG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR34\">Chen, L., Zhen, W. &amp; Peng, D. Research on digital tool in cognitive assessment: a bibliometric analysis. Front. Psychiatry <a href=\"https:\/\/doi.org\/10.3389\/fpsyt.2023.1227261\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.3389\/fpsyt.2023.1227261\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.3389\/fpsyt.2023.1227261<\/a> (2023).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR35\">Belleville, S., LaPlume, A. A. &amp; Purkart, R. Web-based cognitive assessment in older adults: where do we stand?. Curr. Opin. Neurol. 36, 491\u2013497 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1097\/WCO.0000000000001192\" data-track-item_id=\"10.1097\/WCO.0000000000001192\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1097%2FWCO.0000000000001192\" aria-label=\"Article reference 35\" data-doi=\"10.1097\/WCO.0000000000001192\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37591303\" aria-label=\"PubMed reference 35\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10487375\" aria-label=\"PubMed Central reference 35\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 35\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Web-based%20cognitive%20assessment%20in%20older%20adults%3A%20where%20do%20we%20stand%3F&amp;journal=Curr.%20Opin.%20Neurol.&amp;doi=10.1097%2FWCO.0000000000001192&amp;volume=36&amp;pages=491-497&amp;publication_year=2023&amp;author=Belleville%2CS&amp;author=LaPlume%2CAA&amp;author=Purkart%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR36\">Mancuso, V. et al. Systematic review of memory assessment in virtual reality: evaluating convergent and divergent validity with traditional neuropsychological measures. Front. Hum. Neurosci. <a href=\"https:\/\/doi.org\/10.3389\/fnhum.2024.1380575\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.3389\/fnhum.2024.1380575\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.3389\/fnhum.2024.1380575<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR37\">Breithaupt, A. G. et al. Review of artificial intelligence for clinical use in Alzheimer\u2019s disease and related dementias. Semin. Neurol. <a href=\"https:\/\/doi.org\/10.1055\/a-2744-9871\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1055\/a-2744-9871\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1055\/a-2744-9871<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR38\">Adnan, T. et al. AI-enabled Parkinson\u2019s disease screening using smile videos. NEJM AI 2, AIoa2400950 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1056\/AIoa2400950\" data-track-item_id=\"10.1056\/AIoa2400950\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1056%2FAIoa2400950\" aria-label=\"Article reference 38\" data-doi=\"10.1056\/AIoa2400950\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 38\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=AI-enabled%20Parkinson%E2%80%99s%20disease%20screening%20using%20smile%20videos&amp;journal=NEJM%20AI&amp;doi=10.1056%2FAIoa2400950&amp;volume=2&amp;publication_year=2025&amp;author=Adnan%2CT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR39\">Deng, D. et al. Interpretable video-based tracking and quantification of parkinsonism clinical motor states. NPJ Parkinsons Dis. 10, 122 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41531-024-00742-x\" data-track-item_id=\"10.1038\/s41531-024-00742-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41531-024-00742-x\" aria-label=\"Article reference 39\" data-doi=\"10.1038\/s41531-024-00742-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38918385\" aria-label=\"PubMed reference 39\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11199701\" aria-label=\"PubMed Central reference 39\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 39\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Interpretable%20video-based%20tracking%20and%20quantification%20of%20parkinsonism%20clinical%20motor%20states&amp;journal=NPJ%20Parkinsons%20Dis.&amp;doi=10.1038%2Fs41531-024-00742-x&amp;volume=10&amp;publication_year=2024&amp;author=Deng%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR40\">Zhang, K. et al. Recent advances in compact portable platforms and gradient hardware for brain MRI. Radiology 315, e241904 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1148\/radiol.241904\" data-track-item_id=\"10.1148\/radiol.241904\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1148%2Fradiol.241904\" aria-label=\"Article reference 40\" data-doi=\"10.1148\/radiol.241904\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40492919\" aria-label=\"PubMed reference 40\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12207646\" aria-label=\"PubMed Central reference 40\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 40\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Recent%20advances%20in%20compact%20portable%20platforms%20and%20gradient%20hardware%20for%20brain%20MRI&amp;journal=Radiology&amp;doi=10.1148%2Fradiol.241904&amp;volume=315&amp;publication_year=2025&amp;author=Zhang%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR41\">Ashton, N. J. et al. Diagnostic accuracy of a plasma phosphorylated tau 217 immunoassay for Alzheimer disease pathology. JAMA Neurol. 81, 255\u2013263 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jamaneurol.2023.5319\" data-track-item_id=\"10.1001\/jamaneurol.2023.5319\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjamaneurol.2023.5319\" aria-label=\"Article reference 41\" data-doi=\"10.1001\/jamaneurol.2023.5319\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38252443\" aria-label=\"PubMed reference 41\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10804282\" aria-label=\"PubMed Central reference 41\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 41\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Diagnostic%20accuracy%20of%20a%20plasma%20phosphorylated%20tau%20217%20immunoassay%20for%20Alzheimer%20disease%20pathology&amp;journal=JAMA%20Neurol.&amp;doi=10.1001%2Fjamaneurol.2023.5319&amp;volume=81&amp;pages=255-263&amp;publication_year=2024&amp;author=Ashton%2CNJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR42\">Janelidze, S. et al. Plasma phosphorylated Tau 217 and A\u03b242\/40 to predict early brain A\u03b2 accumulation in people without cognitive impairment. JAMA Neurol. 81, 947\u2013957 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jamaneurol.2024.2619\" data-track-item_id=\"10.1001\/jamaneurol.2024.2619\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjamaneurol.2024.2619\" aria-label=\"Article reference 42\" data-doi=\"10.1001\/jamaneurol.2024.2619\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39068669\" aria-label=\"PubMed reference 42\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11284634\" aria-label=\"PubMed Central reference 42\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 42\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Plasma%20phosphorylated%20Tau%20217%20and%20A%CE%B242%2F40%20to%20predict%20early%20brain%20A%CE%B2%20accumulation%20in%20people%20without%20cognitive%20impairment&amp;journal=JAMA%20Neurol.&amp;doi=10.1001%2Fjamaneurol.2024.2619&amp;volume=81&amp;pages=947-957&amp;publication_year=2024&amp;author=Janelidze%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR43\">Palmqvist, S. et al. Blood biomarkers to detect Alzheimer disease in primary care and secondary care. JAMA <a href=\"https:\/\/doi.org\/10.1001\/jama.2024.13855\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1001\/jama.2024.13855\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1001\/jama.2024.13855<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR44\">Arnold, M. R. et al. \u03b1-synuclein seed amplification in CSF and brain from patients with different brain distributions of pathological \u03b1-synuclein in the context of co-pathology and non-LBD diagnoses. Ann. Neurol. 92, 650\u2013662 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/ana.26453\" data-track-item_id=\"10.1002\/ana.26453\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Fana.26453\" aria-label=\"Article reference 44\" data-doi=\"10.1002\/ana.26453\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35808984\" aria-label=\"PubMed reference 44\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9489647\" aria-label=\"PubMed Central reference 44\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 44\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=%CE%B1-synuclein%20seed%20amplification%20in%20CSF%20and%20brain%20from%20patients%20with%20different%20brain%20distributions%20of%20pathological%20%CE%B1-synuclein%20in%20the%20context%20of%20co-pathology%20and%20non-LBD%20diagnoses&amp;journal=Ann.%20Neurol.&amp;doi=10.1002%2Fana.26453&amp;volume=92&amp;pages=650-662&amp;publication_year=2022&amp;author=Arnold%2CMR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR45\">Gibbons, C. H. et al. Skin biopsy detection of phosphorylated \u03b1-synuclein in patients with synucleinopathies. JAMA 331, 1298\u20131306 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jama.2024.0792\" data-track-item_id=\"10.1001\/jama.2024.0792\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjama.2024.0792\" aria-label=\"Article reference 45\" data-doi=\"10.1001\/jama.2024.0792\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38506839\" aria-label=\"PubMed reference 45\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10955354\" aria-label=\"PubMed Central reference 45\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 45\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Skin%20biopsy%20detection%20of%20phosphorylated%20%CE%B1-synuclein%20in%20patients%20with%20synucleinopathies&amp;journal=JAMA&amp;doi=10.1001%2Fjama.2024.0792&amp;volume=331&amp;pages=1298-1306&amp;publication_year=2024&amp;author=Gibbons%2CCH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR46\">Samudra, N. et al. Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort. Alzheimers Dement. 20, 3334\u20133341 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/alz.13799\" data-track-item_id=\"10.1002\/alz.13799\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Falz.13799\" aria-label=\"Article reference 46\" data-doi=\"10.1002\/alz.13799\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38539061\" aria-label=\"PubMed reference 46\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11095442\" aria-label=\"PubMed Central reference 46\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 46\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Clinicopathological%20correlation%20of%20cerebrospinal%20fluid%20alpha-synuclein%20seed%20amplification%20assay%20in%20a%20behavioral%20neurology%20autopsy%20cohort&amp;journal=Alzheimers%20Dement.&amp;doi=10.1002%2Falz.13799&amp;volume=20&amp;pages=3334-3341&amp;publication_year=2024&amp;author=Samudra%2CN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR47\">Bouwman, F. H. et al. Clinical application of CSF biomarkers for Alzheimer\u2019s disease: from rationale to ratios. Alzheimers Dement. 14, e12314 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 47\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Clinical%20application%20of%20CSF%20biomarkers%20for%20Alzheimer%E2%80%99s%20disease%3A%20from%20rationale%20to%20ratios&amp;journal=Alzheimers%20Dement.&amp;volume=14&amp;publication_year=2022&amp;author=Bouwman%2CFH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR48\">Dubois, B. et al. Alzheimer disease as a clinical-biological construct\u2014an International Working Group recommendation. JAMA Neurol. <a href=\"https:\/\/doi.org\/10.1001\/jamaneurol.2024.3770\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1001\/jamaneurol.2024.3770\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1001\/jamaneurol.2024.3770<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR49\">Jasodanand, V. H., Bellitti, M. &amp; Kolachalama, V. B. An AI-first framework for multimodal data in Alzheimer\u2019s disease and related dementias. Alzheimers Dement. 21, e70719 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/alz.70719\" data-track-item_id=\"10.1002\/alz.70719\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Falz.70719\" aria-label=\"Article reference 49\" data-doi=\"10.1002\/alz.70719\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40983947\" aria-label=\"PubMed reference 49\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12453944\" aria-label=\"PubMed Central reference 49\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 49\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=An%20AI-first%20framework%20for%20multimodal%20data%20in%20Alzheimer%E2%80%99s%20disease%20and%20related%20dementias&amp;journal=Alzheimers%20Dement.&amp;doi=10.1002%2Falz.70719&amp;volume=21&amp;publication_year=2025&amp;author=Jasodanand%2CVH&amp;author=Bellitti%2CM&amp;author=Kolachalama%2CVB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR50\">Wilkinson, M. D. et al. The FAIR Guiding principles for scientific data management and stewardship. Sci. Data 3, 160018 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/sdata.2016.18\" data-track-item_id=\"10.1038\/sdata.2016.18\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fsdata.2016.18\" aria-label=\"Article reference 50\" data-doi=\"10.1038\/sdata.2016.18\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=26978244\" aria-label=\"PubMed reference 50\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4792175\" aria-label=\"PubMed Central reference 50\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 50\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20FAIR%20Guiding%20principles%20for%20scientific%20data%20management%20and%20stewardship&amp;journal=Sci.%20Data&amp;doi=10.1038%2Fsdata.2016.18&amp;volume=3&amp;publication_year=2016&amp;author=Wilkinson%2CMD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR51\">Shah, N. H. et al. A nationwide network of health ai assurance laboratories. JAMA 331, 245\u2013249 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jama.2023.26930\" data-track-item_id=\"10.1001\/jama.2023.26930\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjama.2023.26930\" aria-label=\"Article reference 51\" data-doi=\"10.1001\/jama.2023.26930\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38117493\" aria-label=\"PubMed reference 51\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 51\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20nationwide%20network%20of%20health%20ai%20assurance%20laboratories&amp;journal=JAMA&amp;doi=10.1001%2Fjama.2023.26930&amp;volume=331&amp;pages=245-249&amp;publication_year=2024&amp;author=Shah%2CNH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR52\">HL7 International. FHIR R5: fast healthcare interoperability resources. hl7.org <a href=\"http:\/\/www.hl7.org\/fhir\/index.html\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/www.hl7.org\/fhir\/index.html\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.hl7.org\/fhir\/index.html<\/a> (2023).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR53\">SMART Health IT. smarthealthit.org <a href=\"https:\/\/smarthealthit.org\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/smarthealthit.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/smarthealthit.org\/<\/a> (accessed 25 October 2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR54\">Oracle Health. Oracle Health Millennium Platform APIs. oracle.com <a href=\"https:\/\/docs.oracle.com\/en\/industries\/health\/millennium-platform-apis\/index.html\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/docs.oracle.com\/en\/industries\/health\/millennium-platform-apis\/index.html\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/docs.oracle.com\/en\/industries\/health\/millennium-platform-apis\/index.html<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR55\">Epic Systems. Epic\u2019s home for data sharing and developer tools. epic.com <a href=\"http:\/\/open.epic.com\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/open.epic.com\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/open.epic.com\/<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR56\">Brown, E. G. et al. Enhancing clinical information display to improve patient encounters: human-centered design and evaluation of the Parkinson Disease-BRIDGE platform. JMIR Hum. Factors 9, e33967 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.2196\/33967\" data-track-item_id=\"10.2196\/33967\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.2196%2F33967\" aria-label=\"Article reference 56\" data-doi=\"10.2196\/33967\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35522472\" aria-label=\"PubMed reference 56\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9123539\" aria-label=\"PubMed Central reference 56\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 56\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Enhancing%20clinical%20information%20display%20to%20improve%20patient%20encounters%3A%20human-centered%20design%20and%20evaluation%20of%20the%20Parkinson%20Disease-BRIDGE%20platform&amp;journal=JMIR%20Hum.%20Factors&amp;doi=10.2196%2F33967&amp;volume=9&amp;publication_year=2022&amp;author=Brown%2CEG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR57\">Park, W. Y. et al. Breaking data silos: incorporating the DICOM imaging standard into the OMOP CDM to enable multimodal research. J. Am. Med. Inform. Assoc. 32, 1533\u20131541 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40680297\" aria-label=\"PubMed reference 57\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12451937\" aria-label=\"PubMed Central reference 57\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 57\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Breaking%20data%20silos%3A%20incorporating%20the%20DICOM%20imaging%20standard%20into%20the%20OMOP%20CDM%20to%20enable%20multimodal%20research&amp;journal=J.%20Am.%20Med.%20Inform.%20Assoc.&amp;volume=32&amp;pages=1533-1541&amp;publication_year=2025&amp;author=Park%2CWY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR58\">Lau-Min, K. S. et al. Impact of integrating genomic data into the electronic health record on genetics care delivery. Genet. Med. 24, 2338\u20132350 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.gim.2022.08.009\" data-track-item_id=\"10.1016\/j.gim.2022.08.009\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.gim.2022.08.009\" aria-label=\"Article reference 58\" data-doi=\"10.1016\/j.gim.2022.08.009\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36107166\" aria-label=\"PubMed reference 58\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10176082\" aria-label=\"PubMed Central reference 58\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 58\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Impact%20of%20integrating%20genomic%20data%20into%20the%20electronic%20health%20record%20on%20genetics%20care%20delivery&amp;journal=Genet.%20Med.&amp;doi=10.1016%2Fj.gim.2022.08.009&amp;volume=24&amp;pages=2338-2350&amp;publication_year=2022&amp;author=Lau-Min%2CKS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR59\">Hoffman, S. L. et al. Comprehensive real time remote monitoring for Parkinson\u2019s disease using quantitative DigitoGraphy. NPJ Parkinsons Dis. 10, 137 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41531-024-00751-w\" data-track-item_id=\"10.1038\/s41531-024-00751-w\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41531-024-00751-w\" aria-label=\"Article reference 59\" data-doi=\"10.1038\/s41531-024-00751-w\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39068150\" aria-label=\"PubMed reference 59\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11283542\" aria-label=\"PubMed Central reference 59\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 59\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Comprehensive%20real%20time%20remote%20monitoring%20for%20Parkinson%E2%80%99s%20disease%20using%20quantitative%20DigitoGraphy&amp;journal=NPJ%20Parkinsons%20Dis.&amp;doi=10.1038%2Fs41531-024-00751-w&amp;volume=10&amp;publication_year=2024&amp;author=Hoffman%2CSL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR60\">McHugh, C. P., Clement, M. H. S. &amp; Phatak, M. AD Workbench: transforming Alzheimer\u2019s research with secure, global, and collaborative data sharing and analysis. Alzheimers Dement. 21, e70278 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/alz.70278\" data-track-item_id=\"10.1002\/alz.70278\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Falz.70278\" aria-label=\"Article reference 60\" data-doi=\"10.1002\/alz.70278\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40387289\" aria-label=\"PubMed reference 60\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12086970\" aria-label=\"PubMed Central reference 60\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 60\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=AD%20Workbench%3A%20transforming%20Alzheimer%E2%80%99s%20research%20with%20secure%2C%20global%2C%20and%20collaborative%20data%20sharing%20and%20analysis&amp;journal=Alzheimers%20Dement.&amp;doi=10.1002%2Falz.70278&amp;volume=21&amp;publication_year=2025&amp;author=McHugh%2CCP&amp;author=Clement%2CMHS&amp;author=Phatak%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR61\">Brat, G. A., Mandel, J. C. &amp; McDermott, M. B. A. Do we need data standards in the era of large language models?. NEJM AI 1, AIe2400548 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1056\/AIe2400548\" data-track-item_id=\"10.1056\/AIe2400548\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1056%2FAIe2400548\" aria-label=\"Article reference 61\" data-doi=\"10.1056\/AIe2400548\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 61\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Do%20we%20need%20data%20standards%20in%20the%20era%20of%20large%20language%20models%3F&amp;journal=NEJM%20AI&amp;doi=10.1056%2FAIe2400548&amp;volume=1&amp;publication_year=2024&amp;author=Brat%2CGA&amp;author=Mandel%2CJC&amp;author=McDermott%2CMBA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR62\">Savage, T., Nayak, A., Gallo, R., Rangan, E. &amp; Chen, J. H. Diagnostic reasoning prompts reveal the potential for large language model interpretability in medicine. NPJ Digit. Med. 7, 20 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41746-024-01010-1\" data-track-item_id=\"10.1038\/s41746-024-01010-1\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41746-024-01010-1\" aria-label=\"Article reference 62\" data-doi=\"10.1038\/s41746-024-01010-1\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38267608\" aria-label=\"PubMed reference 62\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10808088\" aria-label=\"PubMed Central reference 62\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 62\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Diagnostic%20reasoning%20prompts%20reveal%20the%20potential%20for%20large%20language%20model%20interpretability%20in%20medicine&amp;journal=NPJ%20Digit.%20Med.&amp;doi=10.1038%2Fs41746-024-01010-1&amp;volume=7&amp;publication_year=2024&amp;author=Savage%2CT&amp;author=Nayak%2CA&amp;author=Gallo%2CR&amp;author=Rangan%2CE&amp;author=Chen%2CJH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR63\">Esteva, A. et al. A guide to deep learning in healthcare. Nat. Med. 25, 24\u201329 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41591-018-0316-z\" data-track-item_id=\"10.1038\/s41591-018-0316-z\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41591-018-0316-z\" aria-label=\"Article reference 63\" data-doi=\"10.1038\/s41591-018-0316-z\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30617335\" aria-label=\"PubMed reference 63\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 63\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20guide%20to%20deep%20learning%20in%20healthcare&amp;journal=Nat.%20Med.&amp;doi=10.1038%2Fs41591-018-0316-z&amp;volume=25&amp;pages=24-29&amp;publication_year=2019&amp;author=Esteva%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR64\">Bron, E. E. et al. Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: the CADDementia challenge. Neuroimage 111, 562\u2013579 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.neuroimage.2015.01.048\" data-track-item_id=\"10.1016\/j.neuroimage.2015.01.048\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.neuroimage.2015.01.048\" aria-label=\"Article reference 64\" data-doi=\"10.1016\/j.neuroimage.2015.01.048\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25652394\" aria-label=\"PubMed reference 64\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4943029\" aria-label=\"PubMed Central reference 64\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 64\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Standardized%20evaluation%20of%20algorithms%20for%20computer-aided%20diagnosis%20of%20dementia%20based%20on%20structural%20MRI%3A%20the%20CADDementia%20challenge&amp;journal=Neuroimage&amp;doi=10.1016%2Fj.neuroimage.2015.01.048&amp;volume=111&amp;pages=562-579&amp;publication_year=2015&amp;author=Bron%2CEE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR65\">Xue, C. et al. AI-based differential diagnosis of dementia etiologies on multimodal data. Nat. Med. 30, 2977\u20132989 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41591-024-03118-z\" data-track-item_id=\"10.1038\/s41591-024-03118-z\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41591-024-03118-z\" aria-label=\"Article reference 65\" data-doi=\"10.1038\/s41591-024-03118-z\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38965435\" aria-label=\"PubMed reference 65\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11485262\" aria-label=\"PubMed Central reference 65\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 65\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=AI-based%20differential%20diagnosis%20of%20dementia%20etiologies%20on%20multimodal%20data&amp;journal=Nat.%20Med.&amp;doi=10.1038%2Fs41591-024-03118-z&amp;volume=30&amp;pages=2977-2989&amp;publication_year=2024&amp;author=Xue%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR66\">Rauschecker, A. M. et al. Artificial intelligence system approaching neuroradiologist-level differential diagnosis accuracy at brain MRI. Radiology 295, 626\u2013637 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1148\/radiol.2020190283\" data-track-item_id=\"10.1148\/radiol.2020190283\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1148%2Fradiol.2020190283\" aria-label=\"Article reference 66\" data-doi=\"10.1148\/radiol.2020190283\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32255417\" aria-label=\"PubMed reference 66\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7263320\" aria-label=\"PubMed Central reference 66\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 66\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Artificial%20intelligence%20system%20approaching%20neuroradiologist-level%20differential%20diagnosis%20accuracy%20at%20brain%20MRI&amp;journal=Radiology&amp;doi=10.1148%2Fradiol.2020190283&amp;volume=295&amp;pages=626-637&amp;publication_year=2020&amp;author=Rauschecker%2CAM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR67\">Leming, M. &amp; Im, H. Differential dementia detection from multimodal brain images in a real-world dataset. Alzheimers Dement. 21, e70362 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/alz.70362\" data-track-item_id=\"10.1002\/alz.70362\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Falz.70362\" aria-label=\"Article reference 67\" data-doi=\"10.1002\/alz.70362\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40596742\" aria-label=\"PubMed reference 67\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12213449\" aria-label=\"PubMed Central reference 67\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 67\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Differential%20dementia%20detection%20from%20multimodal%20brain%20images%20in%20a%20real-world%20dataset&amp;journal=Alzheimers%20Dement.&amp;doi=10.1002%2Falz.70362&amp;volume=21&amp;publication_year=2025&amp;author=Leming%2CM&amp;author=Im%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR68\">Qiu, S. et al. Multimodal deep learning for Alzheimer\u2019s disease dementia assessment. Nat. Commun. 13, 3404 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41467-022-31037-5\" data-track-item_id=\"10.1038\/s41467-022-31037-5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41467-022-31037-5\" aria-label=\"Article reference 68\" data-doi=\"10.1038\/s41467-022-31037-5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35725739\" aria-label=\"PubMed reference 68\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9209452\" aria-label=\"PubMed Central reference 68\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 68\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Multimodal%20deep%20learning%20for%20Alzheimer%E2%80%99s%20disease%20dementia%20assessment&amp;journal=Nat.%20Commun.&amp;doi=10.1038%2Fs41467-022-31037-5&amp;volume=13&amp;publication_year=2022&amp;author=Qiu%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR69\">Jasodanand, V. H. et al. AI-driven fusion of multimodal data for Alzheimer\u2019s disease biomarker assessment. Nat. Commun. 16, 7407 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41467-025-62590-4\" data-track-item_id=\"10.1038\/s41467-025-62590-4\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41467-025-62590-4\" aria-label=\"Article reference 69\" data-doi=\"10.1038\/s41467-025-62590-4\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40789853\" aria-label=\"PubMed reference 69\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12339743\" aria-label=\"PubMed Central reference 69\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 69\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=AI-driven%20fusion%20of%20multimodal%20data%20for%20Alzheimer%E2%80%99s%20disease%20biomarker%20assessment&amp;journal=Nat.%20Commun.&amp;doi=10.1038%2Fs41467-025-62590-4&amp;volume=16&amp;publication_year=2025&amp;author=Jasodanand%2CVH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR70\">Tanabe, J. et al. Automated volumetric software in dementia: help or hindrance to the neuroradiologist?. AJNR Am. J. Neuroradiol. 45, 1737\u20131744 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.3174\/ajnr.A8406\" data-track-item_id=\"10.3174\/ajnr.A8406\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.3174%2Fajnr.A8406\" aria-label=\"Article reference 70\" data-doi=\"10.3174\/ajnr.A8406\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39362700\" aria-label=\"PubMed reference 70\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11543079\" aria-label=\"PubMed Central reference 70\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 70\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Automated%20volumetric%20software%20in%20dementia%3A%20help%20or%20hindrance%20to%20the%20neuroradiologist%3F&amp;journal=AJNR%20Am.%20J.%20Neuroradiol.&amp;doi=10.3174%2Fajnr.A8406&amp;volume=45&amp;pages=1737-1744&amp;publication_year=2024&amp;author=Tanabe%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR71\">Haller, S. et al. Basic MR sequence parameters systematically bias automated brain volume estimation. Neuroradiology 58, 1153\u20131160 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s00234-016-1737-3\" data-track-item_id=\"10.1007\/s00234-016-1737-3\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s00234-016-1737-3\" aria-label=\"Article reference 71\" data-doi=\"10.1007\/s00234-016-1737-3\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=27623782\" aria-label=\"PubMed reference 71\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 71\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Basic%20MR%20sequence%20parameters%20systematically%20bias%20automated%20brain%20volume%20estimation&amp;journal=Neuroradiology&amp;doi=10.1007%2Fs00234-016-1737-3&amp;volume=58&amp;pages=1153-1160&amp;publication_year=2016&amp;author=Haller%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR72\">Wittens, M. M. J. et al. Diagnostic performance of automated MRI volumetry by icobrain dm for Alzheimer\u2019s disease in a clinical setting: a REMEMBER study. J. Alzheimers Dis. 83, 623\u2013639 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.3233\/JAD-210450\" data-track-item_id=\"10.3233\/JAD-210450\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.3233%2FJAD-210450\" aria-label=\"Article reference 72\" data-doi=\"10.3233\/JAD-210450\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34334402\" aria-label=\"PubMed reference 72\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8543261\" aria-label=\"PubMed Central reference 72\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 72\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Diagnostic%20performance%20of%20automated%20MRI%20volumetry%20by%20icobrain%20dm%20for%20Alzheimer%E2%80%99s%20disease%20in%20a%20clinical%20setting%3A%20a%20REMEMBER%20study&amp;journal=J.%20Alzheimers%20Dis.&amp;doi=10.3233%2FJAD-210450&amp;volume=83&amp;pages=623-639&amp;publication_year=2021&amp;author=Wittens%2CMMJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR73\">Yu, K. H., Beam, A. L. &amp; Kohane, I. S. Artificial intelligence in healthcare. Nat. Biomed. Eng. 2, 719\u2013731 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41551-018-0305-z\" data-track-item_id=\"10.1038\/s41551-018-0305-z\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41551-018-0305-z\" aria-label=\"Article reference 73\" data-doi=\"10.1038\/s41551-018-0305-z\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31015651\" aria-label=\"PubMed reference 73\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 73\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Artificial%20intelligence%20in%20healthcare&amp;journal=Nat.%20Biomed.%20Eng.&amp;doi=10.1038%2Fs41551-018-0305-z&amp;volume=2&amp;pages=719-731&amp;publication_year=2018&amp;author=Yu%2CKH&amp;author=Beam%2CAL&amp;author=Kohane%2CIS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR74\">Aristidou, A., Jena, R. &amp; Topol, E. J. Bridging the chasm between AI and clinical implementation. Lancet 399, 620 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/S0140-6736(22)00235-5\" data-track-item_id=\"10.1016\/S0140-6736(22)00235-5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2FS0140-6736%2822%2900235-5\" aria-label=\"Article reference 74\" data-doi=\"10.1016\/S0140-6736(22)00235-5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35151388\" aria-label=\"PubMed reference 74\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 74\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Bridging%20the%20chasm%20between%20AI%20and%20clinical%20implementation&amp;journal=Lancet&amp;doi=10.1016%2FS0140-6736%2822%2900235-5&amp;volume=399&amp;publication_year=2022&amp;author=Aristidou%2CA&amp;author=Jena%2CR&amp;author=Topol%2CEJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR75\">Schubert, M. C., Wick, W. &amp; Venkataramani, V. Performance of large language models on a neurology board\u2013style examination. JAMA Netw. Open 6, e2346721 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jamanetworkopen.2023.46721\" data-track-item_id=\"10.1001\/jamanetworkopen.2023.46721\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjamanetworkopen.2023.46721\" aria-label=\"Article reference 75\" data-doi=\"10.1001\/jamanetworkopen.2023.46721\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38060223\" aria-label=\"PubMed reference 75\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10704278\" aria-label=\"PubMed Central reference 75\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 75\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Performance%20of%20large%20language%20models%20on%20a%20neurology%20board%E2%80%93style%20examination&amp;journal=JAMA%20Netw.%20Open&amp;doi=10.1001%2Fjamanetworkopen.2023.46721&amp;volume=6&amp;publication_year=2023&amp;author=Schubert%2CMC&amp;author=Wick%2CW&amp;author=Venkataramani%2CV\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR76\">Koga, S., Martin, N. B. &amp; Dickson, D. W. Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders. Brain Pathol. 34, e13207 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/bpa.13207\" data-track-item_id=\"10.1111\/bpa.13207\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fbpa.13207\" aria-label=\"Article reference 76\" data-doi=\"10.1111\/bpa.13207\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37553205\" aria-label=\"PubMed reference 76\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11006994\" aria-label=\"PubMed Central reference 76\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 76\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evaluating%20the%20performance%20of%20large%20language%20models%3A%20ChatGPT%20and%20Google%20Bard%20in%20generating%20differential%20diagnoses%20in%20clinicopathological%20conferences%20of%20neurodegenerative%20disorders&amp;journal=Brain%20Pathol.&amp;doi=10.1111%2Fbpa.13207&amp;volume=34&amp;publication_year=2023&amp;author=Koga%2CS&amp;author=Martin%2CNB&amp;author=Dickson%2CDW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR77\">Ayers, J. W. et al. Comparing Physician and artificial intelligence chatbot responses to patient questions posted to a public social media forum. JAMA Intern. Med. 183, 589\u2013596 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jamainternmed.2023.1838\" data-track-item_id=\"10.1001\/jamainternmed.2023.1838\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjamainternmed.2023.1838\" aria-label=\"Article reference 77\" data-doi=\"10.1001\/jamainternmed.2023.1838\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37115527\" aria-label=\"PubMed reference 77\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10148230\" aria-label=\"PubMed Central reference 77\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 77\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Comparing%20Physician%20and%20artificial%20intelligence%20chatbot%20responses%20to%20patient%20questions%20posted%20to%20a%20public%20social%20media%20forum&amp;journal=JAMA%20Intern.%20Med.&amp;doi=10.1001%2Fjamainternmed.2023.1838&amp;volume=183&amp;pages=589-596&amp;publication_year=2023&amp;author=Ayers%2CJW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR78\">Gallingani, C. et al. Agentic generative artificial intelligence system for classification of pathology-confirmed primary progressive aphasia variants. Preprint at medRxiv <a href=\"https:\/\/doi.org\/10.1101\/2025.10.28.25338977\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1101\/2025.10.28.25338977\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1101\/2025.10.28.25338977<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR79\">Saab, K., Park, C. &amp; Strother, T. et al. Advancing conversational diagnostic AI with multimodal reasoning. Nat. Med. 32, 1726\u20131736 (2026).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41591-026-04371-0\" data-track-item_id=\"10.1038\/s41591-026-04371-0\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41591-026-04371-0\" aria-label=\"Article reference 79\" data-doi=\"10.1038\/s41591-026-04371-0\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=42135531\" aria-label=\"PubMed reference 79\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC13190284\" aria-label=\"PubMed Central reference 79\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 79\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Advancing%20conversational%20diagnostic%20AI%20with%20multimodal%20reasoning&amp;journal=Nat.%20Med.&amp;doi=10.1038%2Fs41591-026-04371-0&amp;volume=32&amp;pages=1726-1736&amp;publication_year=2026&amp;author=Saab%2CK&amp;author=Park%2CC&amp;author=Strother%2CT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR80\">Saab, K. et al. Advancing conversational diagnostic AI with multimodal reasoning. Preprint at <a href=\"http:\/\/arxiv.org\/abs\/2505.04653\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/arxiv.org\/abs\/2505.04653\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/arxiv.org\/abs\/2505.04653<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR81\">El Arab, R. A. &amp; Al Moosa, O. A. Systematic review of cost effectiveness and budget impact of artificial intelligence in healthcare. NPJ Digit. Med. 8, 548 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41746-025-01722-y\" data-track-item_id=\"10.1038\/s41746-025-01722-y\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41746-025-01722-y\" aria-label=\"Article reference 81\" data-doi=\"10.1038\/s41746-025-01722-y\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40858882\" aria-label=\"PubMed reference 81\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12381244\" aria-label=\"PubMed Central reference 81\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 81\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Systematic%20review%20of%20cost%20effectiveness%20and%20budget%20impact%20of%20artificial%20intelligence%20in%20healthcare&amp;journal=NPJ%20Digit.%20Med.&amp;doi=10.1038%2Fs41746-025-01722-y&amp;volume=8&amp;publication_year=2025&amp;author=El%20Arab%2CRA&amp;author=Moosa%2COA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR82\">Aye, S., Handels, R., Winblad, B. &amp; J\u00f6nsson, L. Optimising Alzheimer\u2019s disease diagnosis and treatment: assessing cost-utility of integrating blood biomarkers in clinical practice for disease-modifying treatment. J. Prev. Alzheimers Dis. 11, 928\u2013942 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.14283\/jpad.2024.67\" data-track-item_id=\"10.14283\/jpad.2024.67\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.14283%2Fjpad.2024.67\" aria-label=\"Article reference 82\" data-doi=\"10.14283\/jpad.2024.67\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39044504\" aria-label=\"PubMed reference 82\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11266371\" aria-label=\"PubMed Central reference 82\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 82\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Optimising%20Alzheimer%E2%80%99s%20disease%20diagnosis%20and%20treatment%3A%20assessing%20cost-utility%20of%20integrating%20blood%20biomarkers%20in%20clinical%20practice%20for%20disease-modifying%20treatment&amp;journal=J.%20Prev.%20Alzheimers%20Dis.&amp;doi=10.14283%2Fjpad.2024.67&amp;volume=11&amp;pages=928-942&amp;publication_year=2024&amp;author=Aye%2CS&amp;author=Handels%2CR&amp;author=Winblad%2CB&amp;author=J%C3%B6nsson%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR83\">Bharadwaj, P. et al. Unlocking the value: quantifying the return on investment of hospital artificial intelligence. J. Am. Coll. Radiol. 21, 1677\u20131685 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.jacr.2024.02.034\" data-track-item_id=\"10.1016\/j.jacr.2024.02.034\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.jacr.2024.02.034\" aria-label=\"Article reference 83\" data-doi=\"10.1016\/j.jacr.2024.02.034\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38499053\" aria-label=\"PubMed reference 83\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 83\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Unlocking%20the%20value%3A%20quantifying%20the%20return%20on%20investment%20of%20hospital%20artificial%20intelligence&amp;journal=J.%20Am.%20Coll.%20Radiol.&amp;doi=10.1016%2Fj.jacr.2024.02.034&amp;volume=21&amp;pages=1677-1685&amp;publication_year=2024&amp;author=Bharadwaj%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR84\">Stanford HAI. The 2025 AI Index Report. hai.stanford.edu <a href=\"https:\/\/hai.stanford.edu\/ai-index\/2025-ai-index-report\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/hai.stanford.edu\/ai-index\/2025-ai-index-report\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/hai.stanford.edu\/ai-index\/2025-ai-index-report\/<\/a> (accessed 11 October 2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR85\">Parikh, R. B. &amp; Helmchen, L. A. Paying for artificial intelligence in medicine. NPJ Digit. Med. 5, 63 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41746-022-00609-6\" data-track-item_id=\"10.1038\/s41746-022-00609-6\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41746-022-00609-6\" aria-label=\"Article reference 85\" data-doi=\"10.1038\/s41746-022-00609-6\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35595986\" aria-label=\"PubMed reference 85\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9123184\" aria-label=\"PubMed Central reference 85\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 85\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Paying%20for%20artificial%20intelligence%20in%20medicine&amp;journal=NPJ%20Digit.%20Med.&amp;doi=10.1038%2Fs41746-022-00609-6&amp;volume=5&amp;publication_year=2022&amp;author=Parikh%2CRB&amp;author=Helmchen%2CLA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR86\">Peterson Health Technology Institute. Adoption of artificial intelligence in healthcare delivery systems: early applications and impacts. phti.org <a href=\"http:\/\/phti.org\/ai-adoption-early-applications-impacts\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/phti.org\/ai-adoption-early-applications-impacts\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/phti.org\/ai-adoption-early-applications-impacts\/<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR87\">Tardo, L. et al. Evaluation of the impact of neurology electronic consults (e-consults): experiences of a neurology resident clinic in a safety-net hospital. J. Telemed. Telecare 31, 1270\u20131277 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1177\/1357633X241273051\" data-track-item_id=\"10.1177\/1357633X241273051\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1177%2F1357633X241273051\" aria-label=\"Article reference 87\" data-doi=\"10.1177\/1357633X241273051\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39158496\" aria-label=\"PubMed reference 87\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 87\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evaluation%20of%20the%20impact%20of%20neurology%20electronic%20consults%20%28e-consults%29%3A%20experiences%20of%20a%20neurology%20resident%20clinic%20in%20a%20safety-net%20hospital&amp;journal=J.%20Telemed.%20Telecare&amp;doi=10.1177%2F1357633X241273051&amp;volume=31&amp;pages=1270-1277&amp;publication_year=2025&amp;author=Tardo%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR88\">Bedi, S. et al. Testing and evaluation of health care applications of large language models: a systematic review. JAMA <a href=\"https:\/\/doi.org\/10.1001\/jama.2024.21700\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1001\/jama.2024.21700\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1001\/jama.2024.21700<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR89\">The Federal Register\/FIND. Health data, technology, and interoperability: certification program updates, algorithm transparency, and information sharing. Vol 89, 1192. proquest.com <a href=\"http:\/\/www.proquest.com\/docview\/2912085944\/citation\/14F0AB28E9DD4318PQ\/1\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/www.proquest.com\/docview\/2912085944\/citation\/14F0AB28E9DD4318PQ\/1\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.proquest.com\/docview\/2912085944\/citation\/14F0AB28E9DD4318PQ\/1<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR90\">Goh, E. et al. Large language model influence on diagnostic reasoning: a randomized clinical trial. JAMA Netw. Open 7, e2440969 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jamanetworkopen.2024.40969\" data-track-item_id=\"10.1001\/jamanetworkopen.2024.40969\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjamanetworkopen.2024.40969\" aria-label=\"Article reference 90\" data-doi=\"10.1001\/jamanetworkopen.2024.40969\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39466245\" aria-label=\"PubMed reference 90\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11519755\" aria-label=\"PubMed Central reference 90\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 90\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Large%20language%20model%20influence%20on%20diagnostic%20reasoning%3A%20a%20randomized%20clinical%20trial&amp;journal=JAMA%20Netw.%20Open&amp;doi=10.1001%2Fjamanetworkopen.2024.40969&amp;volume=7&amp;publication_year=2024&amp;author=Goh%2CE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR91\">Jabbour, S. et al. Measuring the impact of AI in the diagnosis of hospitalized patients: a randomized clinical vignette survey study. JAMA 330, 2275\u20132284 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jama.2023.22295\" data-track-item_id=\"10.1001\/jama.2023.22295\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjama.2023.22295\" aria-label=\"Article reference 91\" data-doi=\"10.1001\/jama.2023.22295\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38112814\" aria-label=\"PubMed reference 91\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10731487\" aria-label=\"PubMed Central reference 91\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 91\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Measuring%20the%20impact%20of%20AI%20in%20the%20diagnosis%20of%20hospitalized%20patients%3A%20a%20randomized%20clinical%20vignette%20survey%20study&amp;journal=JAMA&amp;doi=10.1001%2Fjama.2023.22295&amp;volume=330&amp;pages=2275-2284&amp;publication_year=2023&amp;author=Jabbour%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR92\">Tonmoy, S. M. et al. A comprehensive survey of hallucination mitigation techniques in large language models. Preprint at <a href=\"http:\/\/arxiv.org\/abs\/2401.01313\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/arxiv.org\/abs\/2401.01313\" rel=\"nofollow noopener\" target=\"_blank\">http:\/\/arxiv.org\/abs\/2401.01313<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR93\">Bucher, M. J. J. &amp; Martini, M. Fine-tuned \u2018small\u2019 LLMs (still) significantly outperform zero-shot generative ai models in text classification. Preprint at <a href=\"http:\/\/arxiv.org\/html\/2406.08660v1\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/arxiv.org\/html\/2406.08660v1\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/arxiv.org\/html\/2406.08660v1<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR94\">Hugging Face. Open Medical-LLM Leaderboard &#8211; a Hugging Face Space by openlifescienceai. huggingface.co <a href=\"https:\/\/huggingface.co\/spaces\/openlifescienceai\/open_medical_llm_leaderboard\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/huggingface.co\/spaces\/openlifescienceai\/open_medical_llm_leaderboard\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/huggingface.co\/spaces\/openlifescienceai\/open_medical_llm_leaderboard\/<\/a> (accessed 13 November 2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR95\">Dettmers, T., Pagnoni, A., Holtzman, A. &amp; Zettlemoyer, L. QLORA: efficient finetuning of quantized LLMs. In Proc. 37th Int. Conf. on Neural Information Processing Systems. NIPS \u201923 (eds. Oh, A. et al.) 10088\u201310115 (Curran Associates Inc., 2023).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR96\">Abadir, P. M., Battle, A., Walston, J. D. &amp; Chellappa, R. Enhancing care for older adults and dementia patients with large language models: proceedings of the National Institute on Aging\u2014Artificial Intelligence &amp; Technology Collaboratory for Aging Research Symposium. J. Gerontol. A Biol. Sci. Med. Sci. 79, glae176 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/gerona\/glae176\" data-track-item_id=\"10.1093\/gerona\/glae176\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgerona%2Fglae176\" aria-label=\"Article reference 96\" data-doi=\"10.1093\/gerona\/glae176\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39001657\" aria-label=\"PubMed reference 96\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11341983\" aria-label=\"PubMed Central reference 96\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 96\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Enhancing%20care%20for%20older%20adults%20and%20dementia%20patients%20with%20large%20language%20models%3A%20proceedings%20of%20the%20National%20Institute%20on%20Aging%E2%80%94Artificial%20Intelligence%20%26%20Technology%20Collaboratory%20for%20Aging%20Research%20Symposium&amp;journal=J.%20Gerontol.%20A%20Biol.%20Sci.%20Med.%20Sci.&amp;doi=10.1093%2Fgerona%2Fglae176&amp;volume=79&amp;publication_year=2024&amp;author=Abadir%2CPM&amp;author=Battle%2CA&amp;author=Walston%2CJD&amp;author=Chellappa%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR97\">Obermeyer, Z., Powers, B., Vogeli, C. &amp; Mullainathan, S. Dissecting racial bias in an algorithm used to manage the health of populations. Science 366, 447\u2013453 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1126\/science.aax2342\" data-track-item_id=\"10.1126\/science.aax2342\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1126%2Fscience.aax2342\" aria-label=\"Article reference 97\" data-doi=\"10.1126\/science.aax2342\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31649194\" aria-label=\"PubMed reference 97\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 97\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Dissecting%20racial%20bias%20in%20an%20algorithm%20used%20to%20manage%20the%20health%20of%20populations&amp;journal=Science&amp;doi=10.1126%2Fscience.aax2342&amp;volume=366&amp;pages=447-453&amp;publication_year=2019&amp;author=Obermeyer%2CZ&amp;author=Powers%2CB&amp;author=Vogeli%2CC&amp;author=Mullainathan%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR98\">Leslie, D., Mazumder, A., Peppin, A., Wolters, M. K. &amp; Hagerty, A. Does \u2018AI\u2019 stand for augmenting inequality in the era of COVID-19 healthcare?. BMJ 372, n304 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1136\/bmj.n304\" data-track-item_id=\"10.1136\/bmj.n304\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1136%2Fbmj.n304\" aria-label=\"Article reference 98\" data-doi=\"10.1136\/bmj.n304\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33722847\" aria-label=\"PubMed reference 98\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7958301\" aria-label=\"PubMed Central reference 98\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 98\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Does%20%E2%80%98AI%E2%80%99%20stand%20for%20augmenting%20inequality%20in%20the%20era%20of%20COVID-19%20healthcare%3F&amp;journal=BMJ&amp;doi=10.1136%2Fbmj.n304&amp;volume=372&amp;publication_year=2021&amp;author=Leslie%2CD&amp;author=Mazumder%2CA&amp;author=Peppin%2CA&amp;author=Wolters%2CMK&amp;author=Hagerty%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR99\">Savulescu, J., Giubilini, A., Vandersluis, R. &amp; Mishra, A. Ethics of artificial intelligence in medicine. Singapore Med. J. 65, 150\u2013158 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.4103\/singaporemedj.SMJ-2023-279\" data-track-item_id=\"10.4103\/singaporemedj.SMJ-2023-279\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.4103%2Fsingaporemedj.SMJ-2023-279\" aria-label=\"Article reference 99\" data-doi=\"10.4103\/singaporemedj.SMJ-2023-279\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38527299\" aria-label=\"PubMed reference 99\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7615805\" aria-label=\"PubMed Central reference 99\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 99\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Ethics%20of%20artificial%20intelligence%20in%20medicine&amp;journal=Singapore%20Med.%20J.&amp;doi=10.4103%2Fsingaporemedj.SMJ-2023-279&amp;volume=65&amp;pages=150-158&amp;publication_year=2024&amp;author=Savulescu%2CJ&amp;author=Giubilini%2CA&amp;author=Vandersluis%2CR&amp;author=Mishra%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR100\">US Department of Health and Human Services. IRB considerations on the use of artificial intelligence in human subjects research. hhs.gov <a href=\"http:\/\/www.hhs.gov\/ohrp\/sachrp-committee\/recommendations\/irb-considerations-use-artificial-intelligence-human-subjects-research\/index.html\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/www.hhs.gov\/ohrp\/sachrp-committee\/recommendations\/irb-considerations-use-artificial-intelligence-human-subjects-research\/index.html\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.hhs.gov\/ohrp\/sachrp-committee\/recommendations\/irb-considerations-use-artificial-intelligence-human-subjects-research\/index.html<\/a> (2022).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR101\">Sarkar AR, Chuang YS, Mohammed N, Jiang X. De-identification is not enough: a comparison between de-identified and synthetic clinical notes. Sci Rep. 2024;14(1):29669. <a href=\"https:\/\/doi.org\/10.1038\/s41598-024-81170-y\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1038\/s41598-024-81170-y\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1038\/s41598-024-81170-y<\/a><\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR102\">Broniatowski, D. A. Psychological foundations of explainability and interpretability in artificial intelligence. National Institute of Standards and Technology (US); NIST IR 8367. NIST <a href=\"https:\/\/doi.org\/10.6028\/NIST.IR.8367\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.6028\/NIST.IR.8367\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.6028\/NIST.IR.8367<\/a> (2021).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR103\">Tabassi, E. Artificial Intelligence Risk Management Framework (AI RMF 1.0). National Institute of Standards and Technology (US); NIST AI 100-1. NIST <a href=\"https:\/\/doi.org\/10.6028\/NIST.AI.100-1\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.6028\/NIST.AI.100-1\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.6028\/NIST.AI.100-1<\/a> (2023).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR104\">Phillips, P. J. et al. Four principles of explainable artificial intelligence. National Institute of Standards and Technology (US); NIST IR 8312. NIST <a href=\"https:\/\/doi.org\/10.6028\/NIST.IR.8312\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.6028\/NIST.IR.8312\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.6028\/NIST.IR.8312<\/a> (2021).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR105\">Sim, I. &amp; Cassel, C. The ethics of relational AI \u2014 expanding and implementing the Belmont principles. N. Engl. J. Med. 391, 193\u2013196 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1056\/NEJMp2314771\" data-track-item_id=\"10.1056\/NEJMp2314771\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1056%2FNEJMp2314771\" aria-label=\"Article reference 105\" data-doi=\"10.1056\/NEJMp2314771\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39007542\" aria-label=\"PubMed reference 105\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 105\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20ethics%20of%20relational%20AI%20%E2%80%94%20expanding%20and%20implementing%20the%20Belmont%20principles&amp;journal=N.%20Engl.%20J.%20Med.&amp;doi=10.1056%2FNEJMp2314771&amp;volume=391&amp;pages=193-196&amp;publication_year=2024&amp;author=Sim%2CI&amp;author=Cassel%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR106\">Mello, M. M. &amp; Cohen, I. G. Regulation of health and health care artificial intelligence. JAMA 333, 1769\u20131770 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1001\/jama.2025.3308\" data-track-item_id=\"10.1001\/jama.2025.3308\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1001%2Fjama.2025.3308\" aria-label=\"Article reference 106\" data-doi=\"10.1001\/jama.2025.3308\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40095599\" aria-label=\"PubMed reference 106\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 106\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Regulation%20of%20health%20and%20health%20care%20artificial%20intelligence&amp;journal=JAMA&amp;doi=10.1001%2Fjama.2025.3308&amp;volume=333&amp;pages=1769-1770&amp;publication_year=2025&amp;author=Mello%2CMM&amp;author=Cohen%2CIG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR107\">Dell\u2019Acqua, F. et al. Navigating the jagged technological frontier: field experimental evidence of the effects of AI on knowledge worker productivity and quality. SSRN Electron J. <a href=\"https:\/\/doi.org\/10.2139\/ssrn.4573321\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.2139\/ssrn.4573321\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.2139\/ssrn.4573321<\/a> (2023).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR108\">Bedi, S., Fries, J. A. &amp; Shah, N. H. How to interpret \u2018zero-shot\u2019 results from generative EHR models. Nat. Med. 32, 404\u2013406 (2026).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41591-025-04094-8\" data-track-item_id=\"10.1038\/s41591-025-04094-8\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41591-025-04094-8\" aria-label=\"Article reference 108\" data-doi=\"10.1038\/s41591-025-04094-8\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=41501487\" aria-label=\"PubMed reference 108\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 108\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=How%20to%20interpret%20%E2%80%98zero-shot%E2%80%99%20results%20from%20generative%20EHR%20models&amp;journal=Nat.%20Med.&amp;doi=10.1038%2Fs41591-025-04094-8&amp;volume=32&amp;pages=404-406&amp;publication_year=2026&amp;author=Bedi%2CS&amp;author=Fries%2CJA&amp;author=Shah%2CNH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR109\">Shi, H. et al. Continual learning of large language models: a comprehensive survey. ACM Comput. Surv. 58, 120:1\u2013120:42 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 109\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Continual%20learning%20of%20large%20language%20models%3A%20a%20comprehensive%20survey&amp;journal=ACM%20Comput.%20Surv.&amp;volume=58&amp;pages=120%3A1-120%3A42&amp;publication_year=2025&amp;author=Shi%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR110\">Liu, N. F. et al. Lost in the middle: how language models use long contexts. Trans. Assoc. Comput. Linguist. 12, 157\u2013173 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1162\/tacl_a_00638\" data-track-item_id=\"10.1162\/tacl_a_00638\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1162%2Ftacl_a_00638\" aria-label=\"Article reference 110\" data-doi=\"10.1162\/tacl_a_00638\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 110\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Lost%20in%20the%20middle%3A%20how%20language%20models%20use%20long%20contexts&amp;journal=Trans.%20Assoc.%20Comput.%20Linguist.&amp;doi=10.1162%2Ftacl_a_00638&amp;volume=12&amp;pages=157-173&amp;publication_year=2024&amp;author=Liu%2CNF\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR111\">Gargari, O. K. &amp; Habibi, G. Enhancing medical AI with retrieval-augmented generation: a mini narrative review. Digit. Health <a href=\"https:\/\/doi.org\/10.1177\/20552076251337177\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1177\/20552076251337177\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1177\/20552076251337177<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR112\">He, J. et al. Retrieval-augmented generation in biomedicine: a survey of technologies, datasets, and clinical applications. Preprint at <a href=\"http:\/\/arxiv.org\/abs\/2505.01146\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"http:\/\/arxiv.org\/abs\/2505.01146\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/arxiv.org\/abs\/2505.01146<\/a> (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR113\">Lopopolo, R. Harness engineering: leveraging Codex in an agent-first world. OpenAI <a href=\"https:\/\/openai.com\/index\/harness-engineering\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/openai.com\/index\/harness-engineering\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/openai.com\/index\/harness-engineering\/<\/a> (accessed 27 April 2026).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR114\">Lu, C. et al. Towards end-to-end automation of AI research. Nature 651, 914\u2013919 (2026).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41586-026-10265-5\" data-track-item_id=\"10.1038\/s41586-026-10265-5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41586-026-10265-5\" aria-label=\"Article reference 114\" data-doi=\"10.1038\/s41586-026-10265-5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=41882133\" aria-label=\"PubMed reference 114\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC13017497\" aria-label=\"PubMed Central reference 114\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 114\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Towards%20end-to-end%20automation%20of%20AI%20research&amp;journal=Nature&amp;doi=10.1038%2Fs41586-026-10265-5&amp;volume=651&amp;pages=914-919&amp;publication_year=2026&amp;author=Lu%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR115\">Model Context Protocol. What is the Model Context Protocol (MCP)? modelcontextprotocol.io <a href=\"https:\/\/modelcontextprotocol.io\/docs\/getting-started\/intro\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/modelcontextprotocol.io\/docs\/getting-started\/intro\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/modelcontextprotocol.io\/docs\/getting-started\/intro\/<\/a> (accessed 27 April 2026).<\/p>\n","protected":false},"excerpt":{"rendered":"Hebert, L. E., Weuve, J., Scherr, P. A. &amp; Evans, D. A. 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