{"id":97738,"date":"2026-07-07T13:49:11","date_gmt":"2026-07-07T13:49:11","guid":{"rendered":"https:\/\/www.europesays.com\/ai\/97738\/"},"modified":"2026-07-07T13:49:11","modified_gmt":"2026-07-07T13:49:11","slug":"ai-tool-predicts-immunotherapy-outcomes-in-rare-cancers-md-anderson-study","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ai\/97738\/","title":{"rendered":"AI Tool Predicts Immunotherapy Outcomes in Rare Cancers: MD Anderson Study"},"content":{"rendered":"<p>Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that an artificial intelligence (AI)-based analysis of tumor biopsies can <a href=\"https:\/\/clpmag.com\/diagnostic-technologies\/molecular-diagnostics\/liquid-biopsy-rna-sequencing-immunotherapy-response-breast-cancer\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"text-editor-link-class\">predict responses to immunotherapy<\/a> in patients with rare cancers, according to a <a href=\"https:\/\/jitc.bmj.com\/content\/14\/6\/e014768\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"text-editor-link-class\">study<\/a> published in the Journal for ImmunoTherapy of Cancer.<\/p>\n<p>The analysis, led by <a href=\"https:\/\/faculty.mdanderson.org\/profiles\/aung_naing.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"text-editor-link-class\">Aung Naing<\/a>, MD, professor of investigational cancer therapeutics, builds on <a href=\"https:\/\/www.mdanderson.org\/newsroom\/research-newsroom\/tumor-microenvironment-features-may-predict-immunotherapy-response-in-rare-cancers.h00-159855345.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"text-editor-link-class\">research identifying features<\/a> in the <a href=\"https:\/\/clpmag.com\/disease-states\/cancer\/liquid-biopsy-maps-tumor-microenvironment-immunotherapy-response\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"text-editor-link-class\">tumor microenvironment that predict immunotherapy response<\/a>. The AI tool measures how many immune cells are present within a tumor before treatment and tracks changes in immune cell infiltration during treatment.<\/p>\n<p>\u201cAI-based pathology has the potential to provide clinicians with useful information on both the tumor and its surrounding microenvironment, helping to guide personalized treatment decisions for patients receiving immunotherapy,\u201d says Naing in a release.<\/p>\n<p>Advantages for Clinical Laboratories<\/p>\n<p>While manually counting individual immune and cancer cells on <a href=\"https:\/\/clpmag.com\/diagnostic-technologies\/digital-pathology\/digital-pathology-adoption-framework-clinical-labs\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"text-editor-link-class\">pathology slides<\/a> is labor-intensive, the AI-based tool generates these measurements quickly. The approach utilizes standard pathology slides that are already routinely collected, allowing for longitudinal tracking across multiple biopsies from the same patient.<\/p>\n<p>The study found that an increase in tumor immune infiltration combined with a decrease in tumor content served as a strong predictive metric. Patients with these favorable signals had a 64% lower risk of disease progression or death. These patients lived nearly four times longer on average, with a median survival of 42 months compared to 10 months for those without the markers.<\/p>\n<p>Future Validation Required<\/p>\n<p>Although the results are promising, the researchers note that validation in larger patient populations is required before the approach is ready for clinical use. The study was supported in part by the National Cancer Institute (NCI) and the National Center for Advancing Translational Sciences (NCATS).<\/p>\n<p>\u201cWhile this AI-powered approach needs validation, this is an exciting step forward because it shows that meaningful insights can be extracted from routine pathology samples across a diverse group of rare cancers,\u201d says Naing in a release.<\/p>\n<p>ID <a href=\"https:\/\/www.dreamstime.com\/dropping-chemical-liquid-to-test-tube-laboratory-research-development-concept-scientist-sample-chemistry-medicine-image125378010\" rel=\"nofollow noopener\" target=\"_blank\">125378010<\/a> \u00a9 <a href=\"https:\/\/www.dreamstime.com\/komkrittor_info\" rel=\"nofollow noopener\" target=\"_blank\">Komgrit Pradissagul<\/a> | <a href=\"http:\/\/Dreamstime.com\" rel=\"nofollow noopener\" target=\"_blank\">Dreamstime.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that an artificial intelligence (AI)-based analysis&hellip;\n","protected":false},"author":2,"featured_media":97739,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[24,42823,25,51026,7163,42795,7287,28528,2455,51027,51028,51029],"class_list":["post-97738","post","type-post","status-publish","format-standard","has-post-thumbnail","category-ai","tag-ai","tag-ai-pathology","tag-artificial-intelligence","tag-biopsy-analysis","tag-cancer-diagnostics","tag-clinical-laboratories","tag-digital-pathology","tag-immunotherapy","tag-personalized-medicine","tag-predictive-biomarkers","tag-rare-cancers","tag-tumor-microenvironment"],"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/posts\/97738","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/comments?post=97738"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/posts\/97738\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/media\/97739"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/media?parent=97738"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/categories?post=97738"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ai\/wp-json\/wp\/v2\/tags?post=97738"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}