A child has died in a house fire in Melbourne’s south-west overnight.

Emergency services were called to a house in Newbury Street, Werribee, just after midnight.

Victoria Police said a resident of the home died and a 40-year-old man was taken to hospital with serious burns.

Police tape outside a burnt house.

Police are investigating the cause of the fire at a house in Werribee overnight. (ABC News: Tara Whitchurch)

Fire Rescue Victoria (FRV) have since confirmed the victim was a child.

The child’s grandmother, Tracey, identified the victim as three-year-old Jordan Dashwood.

A child holds a hose while looking at the camera

Three-year-old Jordan Dashwood was killed in a house fire in Werribee. (Supplied)

Relatives told the ABC another child, aged 11, escaped the fire by jumping out of a window.

The injured man is understood to be the father of the two children.

FRV said peer support and counselling have been made available to first responders.

A police car and police tape are seen outside of a house.

Police attend the house in Werribee on Monday morning. (ABC News: Stephanie Ferrier)

FRV said crews arrived at the scene within three minutes of the blaze being reported to find the house fully ablaze.

Police say the circumstances of the fire are being investigated, and an arson chemist will attend the scene.

Anyone with information has been urged to contact CrimeStoppers on 1800 333 000.