Monday morning commuters are facing bumper-to-bumper traffic on a major Perth road after a crash.

Emergency crews are responding to the incident in the centre southbound lane of Kwinana Freeway near the Roe Highway exit in Jandakot.

The crash happened just after 6am on Monday, with all lanes except one shut to motorists.

Main Roads warn of heavy traffic and significant delays in the area.

No injuries have been reported, with a tow truck at the scene working to clear the carnage.

A crash on Great Eastern Highway heading west in Darlington has shut down the left lane.

Police are on the scene and drivers are warned of heavy traffic.

A lane has also been blocked on Mitchell Freeway heading north just after Ocean Reef Road in Heathridge.

The left lane is partially blocked, according to Main Roads, with motorists urged to drive carefully in the area.

An ambulance is at the scene. Injuries are unknown at this stage.

Another crash has caused traffic delays in Warwick where multiple lanes have been blocked.

The crash between two cars unfolded on Warwick Road heading west on the Mitchell Freeway overpass at about 7.30am.

Traffic is slow in the area and motorists are urged to drive with caution.

Traffic on Leach Highway heading west at North Lake Road in Winthrop has been disrupted by a crash too.

The left lane is blocked and traffic is backed up on approach.