\u00c0 l\u2019aide de techniques de microscopie, l\u2019\u00e9quipe de recherche a rep\u00e9r\u00e9 un r\u00e9seau de filaments d\u2019actine d\u00e9ploy\u00e9 \u00e0 la surface de cellules \u00e9pith\u00e9liales de la peau. Ce r\u00e9seau comprend des carrefours en forme d\u2019\u00e9toile et de longs c\u00e2bles reliant des dizaines de cellules entre elles. Cette structure dite supracellulaire peut se contracter et produire une tension \u00e0 la surface des cellules. Elle demeure \u00e9galement dynamique et se r\u00e9organise lorsque les cellules migrent collectivement.<\/p>\n
Des forces transmises sur de longues distances<\/p>\n
Les r\u00e9sultats des travaux indiquent que ce r\u00e9seau d\u2019actine est mobilis\u00e9 dans la transmission des forces m\u00e9caniques sur de longues distances, jusqu\u2019\u00e0 14\u00a0cellules plus loin. Les travaux apportent ainsi un nouvel \u00e9clairage sur les propri\u00e9t\u00e9s biom\u00e9caniques des tissus \u00e9pith\u00e9liaux.<\/p>\n
\u00abCes structures supracellulaires d\u2019actine pourraient jouer un r\u00f4le essentiel dans la fonction de barri\u00e8re assur\u00e9e par ces tissus, souligne Gregory Emery, \u00e9galement professeur au D\u00e9partement de pathologie et biologie cellulaire de l\u2019UdeM. Leur analyse pourrait am\u00e9liorer notre compr\u00e9hension de processus biologiques tels que la morphogen\u00e8se, c\u2019est-\u00e0-dire la formation des tissus et des organes, ou la cicatrisation. Elles offrent \u00e9galement une nouvelle perspective pour explorer certaines maladies touchant les \u00e9pith\u00e9liums.\u00bb<\/p>\n","protected":false},"excerpt":{"rendered":"\u00c0 l\u2019aide de techniques de microscopie, l\u2019\u00e9quipe de recherche a rep\u00e9r\u00e9 un r\u00e9seau de filaments d\u2019actine d\u00e9ploy\u00e9 \u00e0…\n","protected":false},"author":2,"featured_media":160610,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[7],"tags":[18952,13189,10134,7985,39246,30357,30358,1686,2607,61,57,59,58,23,60,62],"class_list":["post-160609","post","type-post","status-publish","format-standard","has-post-thumbnail","category-sciences-et-technologies","tag-biologie-cellulaire","tag-cellule","tag-departement-de-pathologie-et-biologie-cellulaire","tag-faculte-de-medecine","tag-gregory-emery","tag-institut-de-recherche-en-immunologie-et-en-cancerologie-de-luniversite-de-montreal","tag-iric","tag-medecine","tag-recherche","tag-science","tag-science-and-technology","tag-sciences","tag-sciences-et-technologies","tag-suisse","tag-technologies","tag-technology"],"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@ch_fr\/116691366486485259","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/posts\/160609","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/comments?post=160609"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/posts\/160609\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/media\/160610"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/media?parent=160609"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/categories?post=160609"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ch-fr\/wp-json\/wp\/v2\/tags?post=160609"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}