Dualitybio Inc. is getting $45 million up front in a deal with Roche AG\u2019s Genentech unit that could exceed $1 billion upon successful development of next-generation antibody-drug conjugate (ADC) candidates. The collaboration and license agreement centers on the DUPAC, or DualityBio Unique Payload Antibody Conjugate, platform, designed to overcome resistance to older topoisomerase inhibitors-based ADCs.<\/p>\n
BioWorld<\/a> Deals and M&A<\/a> Cancer<\/a> Antibody-drug conjugate<\/a> Asia-Pacific<\/a> U.S.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Dualitybio Inc. is getting $45 million up front in a deal with Roche AG\u2019s Genentech unit that could…\n","protected":false},"author":2,"featured_media":124692,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[124],"tags":[6261,941,8086,2112,8568,60816,60817,1360,265,134,4178,60818,2278],"class_list":["post-124691","post","type-post","status-publish","format-standard","has-post-thumbnail","category-roche","tag-antibody-drug-conjugate","tag-asia-pacific","tag-bioworld","tag-cancer","tag-deals-and-ma","tag-dualitybio-inc","tag-dupac","tag-genentech","tag-oncology","tag-roche","tag-roche-ag","tag-topoisomerase","tag-u-s"],"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@ch\/117203782065115469","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts\/124691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/comments?post=124691"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts\/124691\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/media\/124692"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/media?parent=124691"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/categories?post=124691"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/tags?post=124691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}