{"id":13538,"date":"2026-02-20T01:28:46","date_gmt":"2026-02-20T01:28:46","guid":{"rendered":"https:\/\/www.europesays.com\/ch\/13538\/"},"modified":"2026-02-20T01:28:46","modified_gmt":"2026-02-20T01:28:46","slug":"why-roche-holding-stock-popped-today-2","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ch\/13538\/","title":{"rendered":"Why Roche Holding Stock Popped Today"},"content":{"rendered":"<p>Key Points<\/p>\n<p>Roche reported positive Phase III results on trials of its new multiple sclerosis (MS) drug today.<\/p>\n<p>Fenebrutinib appears effective at treating both relapsing multiple sclerosis and primary progressive multiple sclerosis.<\/p>\n<p>Roche Holding (OTC: RHHBY) stock jumped 3.4% through 1:05 p.m. ET Monday after the <a href=\"https:\/\/www.fool.com\/investing\/stock-market\/market-sectors\/healthcare\/pharmaceutical-stocks\/?utm_source=globeandmail&amp;utm_medium=feed&amp;utm_campaign=article&amp;referring_guid=ce2cb739-2e5d-43a5-be3a-c3358028047c\" target=\"_blank\" rel=\"noopener nofollow\">pharmaceutical giant&#8217;s<\/a> Genentech subsidiary announced positive phase 3 clinical trial results for its fenebrutinib drug for treatment of relapsing multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS).<\/p>\n<p><img decoding=\"async\" fetchpriority=\"high\" alt=\"Scientist in lab coat studies a test tube of fluid while looking at a strand of DNA on a computer screen.\" src=\"https:\/\/barchart-news-media-prod.aws.barchart.com\/FC\/17c00d4e54e6a5a1bcf7578f7ff9b45a\/%3Furl%3Dhttps%253a%252f%252fg.foolcdn.com%252feditorial%252fimages%252f841984%252fscientist-in-lab-coat-studies-a-test-tube-of-fluid-while-looking-at-a-strand-of-dna-on-a-computer-screen.jpg%26amp%3Bw%3D700\"\/><\/p>\n<p class=\"caption\">Image source: Getty Images.<\/p>\n<p>Where to invest $1,000 right now? Our analyst team just revealed what they believe are the 10 best stocks to buy right now. <a href=\"https:\/\/api.fool.com\/infotron\/infotrack\/click?apikey=35527423-a535-4519-a07f-20014582e03e&amp;impression=a0328160-60a2-43dc-8349-6d5a69694c45&amp;url=https%3A%2F%2Fwww.fool.com%2Fmms%2Fmark%2Fe-sa-bbn-bn%3Faid%3D8867%26source%3Disaeditxt0001096%26ftm_cam%3Dsa-bbn-evergreen%26ftm_veh%3Dtop_incontent_pitch_feed_partner%26ftm_pit%3D17547&amp;utm_source=globeandmail&amp;utm_medium=feed&amp;utm_campaign=article&amp;referring_guid=ce2cb739-2e5d-43a5-be3a-c3358028047c\" rel=\"noopener nofollow\" target=\"_blank\">Continue \u00bb<\/a><\/p>\n<p>One drug, two clinical trials<\/p>\n<p>Conducted over more than 96 weeks, the first trial &#8220;significantly reduced the annualized relapse rate (ARR) compared to teriflunomide,&#8221; an RMS drug developed by Sanofi and currently available as a generic from multiple manufacturers.<\/p>\n<p>The second trial compared fenebrutinib to ocrelizumab, an MS drug developed by Roche itself and not available as a generic, in treatment of PPMS. This trial confirmed fenebrutinib is at least &#8220;non-inferior compared to ocrelizumab,&#8221; which in turn is currently &#8220;the only approved therapy in PPMS.&#8221; This second trial lasted more than 120 weeks.<\/p>\n<p>Overall, Roche says &#8220;fenebrutinib substantially reduced the number of relapses in RMS and slowed disability progression in PPMS&#8221; &#8212; two separate uses for one MS drug in a market that&#8217;s been estimated at $27.8 billion in annual sales last year, with likely growth to $46.4 billion by 2033.<\/p>\n<p><a href=\"https:\/\/www.fool.com\/terms\/c\/clinical-development-phases\/?utm_source=globeandmail&amp;utm_medium=feed&amp;utm_campaign=article&amp;referring_guid=ce2cb739-2e5d-43a5-be3a-c3358028047c\" target=\"_blank\" rel=\"noopener nofollow\">Clinical trial work<\/a> on fenebrutinib is ongoing.<\/p>\n<p>Is Roche stock a buy?<\/p>\n<p>Valued in excess of $296 billion, Roche stock sells for 25.3 times trailing earnings but less than 15 times <a href=\"https:\/\/www.fool.com\/investing\/how-to-invest\/stocks\/free-cash-flow\/?utm_source=globeandmail&amp;utm_medium=feed&amp;utm_campaign=article&amp;referring_guid=ce2cb739-2e5d-43a5-be3a-c3358028047c\" target=\"_blank\" rel=\"noopener nofollow\">free cash flow<\/a>. (At $19.9 billion generated over the past year, Roche generates nearly 70% more cash profit than it reports as net income.) The company also pays a very respectable 3.8% <a href=\"https:\/\/www.fool.com\/investing\/stock-market\/types-of-stocks\/dividend-stocks\/dividend-yield\/?utm_source=globeandmail&amp;utm_medium=feed&amp;utm_campaign=article&amp;referring_guid=ce2cb739-2e5d-43a5-be3a-c3358028047c\" target=\"_blank\" rel=\"noopener nofollow\">dividend yield<\/a>.<\/p>\n<p>Were Roche growing just a bit faster than the 6% annualized long-term growth rate that analysts project for it, the stock might already be a buy. As things stand, though, I still need to see Roche stock get cheaper before I can call it a buy.<\/p>\n<p>Should you invest $1,000 in Roche Holding AG right now?<\/p>\n<p>Before you buy stock in Roche Holding AG, consider this:<\/p>\n<p>The Motley Fool Stock Advisor analyst team just identified what they believe are the <a href=\"https:\/\/api.fool.com\/infotron\/infotrack\/click?apikey=35527423-a535-4519-a07f-20014582e03e&amp;impression=70a82110-7326-4d54-805f-ae0e70d750b6&amp;url=https%3A%2F%2Fwww.fool.com%2Fmms%2Fmark%2Fe-sa-bbn-bn%3Faid%3D8867%26source%3Disaeditxt0001093%26ftm_cam%3Dsa-bbn-evergreen%26ftm_veh%3Darticle_pitch_feed_partners%26ftm_pit%3D17514&amp;utm_source=globeandmail&amp;utm_medium=feed&amp;utm_campaign=article&amp;referring_guid=ce2cb739-2e5d-43a5-be3a-c3358028047c\" rel=\"noopener nofollow\" target=\"_blank\">10 best stocks<\/a> for investors to buy now\u2026 and Roche Holding AG wasn\u2019t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.<\/p>\n<p>Consider when Netflix made this list on December 17, 2004&#8230; if you invested $1,000 at the time of our recommendation, you\u2019d have $595,194!* Or when Nvidia made this list on April 15, 2005&#8230; if you invested $1,000 at the time of our recommendation, you\u2019d have $1,153,334!*<\/p>\n<p>Now, it\u2019s worth noting Stock Advisor\u2019s total average return is 1,036% \u2014 a market-crushing outperformance compared to 191% for the S&amp;P 500. Don\u2019t miss out on the latest top 10 list, available when you join Stock Advisor.<\/p>\n<p><a class=\"ticker_pitch\" href=\"https:\/\/api.fool.com\/infotron\/infotrack\/click?apikey=35527423-a535-4519-a07f-20014582e03e&amp;impression=70a82110-7326-4d54-805f-ae0e70d750b6&amp;url=https%3A%2F%2Fwww.fool.com%2Fmms%2Fmark%2Fe-sa-bbn-bn%3Faid%3D8867%26source%3Disaeditxt0001093%26ftm_cam%3Dsa-bbn-evergreen%26ftm_pit%3D17514%26ftm_veh%3Darticle_pitch_feed_partners%26company%3DRoche%2520Holding%2520AG&amp;utm_source=globeandmail&amp;utm_medium=feed&amp;utm_campaign=article&amp;referring_guid=ce2cb739-2e5d-43a5-be3a-c3358028047c\" rel=\"noopener nofollow\" target=\"_blank\">See the 10 stocks \u00bb<\/a><\/p>\n<p>*Stock Advisor returns as of November 10, 2025<\/p>\n<p><a href=\"https:\/\/www.fool.com\/author\/1297\/\" target=\"_blank\" rel=\"noopener nofollow\">Rich Smith<\/a> has no position in any of the stocks mentioned. The Motley Fool recommends Roche Holding AG. The Motley Fool has a <a href=\"https:\/\/www.fool.com\/legal\/fool-disclosure-policy\/\" target=\"_blank\" rel=\"noopener nofollow\">disclosure policy<\/a>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" style=\"display:none;\" referrerpolicy=\"unsafe-url\" src=\"https:\/\/barchart-news-media-prod.aws.barchart.com\/FC\/17c00d4e54e6a5a1bcf7578f7ff9b45a\/pixel%3Fslug%3Dmotleyfoolgm-2025-11-10-why-roche-holding-stock-popped-today\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"Key Points Roche reported positive Phase III results on trials of its new multiple sclerosis (MS) drug today.&hellip;\n","protected":false},"author":2,"featured_media":13539,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[124],"tags":[114,166,39,167,160,161,162,163,9228,3325,134,7986,164,165,436],"class_list":["post-13538","post","type-post","status-publish","format-standard","has-post-thumbnail","category-roche","tag-business","tag-business-news","tag-economy","tag-finance","tag-financial-information","tag-investing","tag-investor","tag-market-news","tag-motley-fool","tag-press-releases","tag-roche","tag-sedar","tag-stock-research","tag-stock-valuation","tag-the-globe-and-mail"],"share_on_mastodon":{"url":"","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts\/13538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/comments?post=13538"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts\/13538\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/media\/13539"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/media?parent=13538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/categories?post=13538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/tags?post=13538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}