{"id":22875,"date":"2026-03-02T11:04:21","date_gmt":"2026-03-02T11:04:21","guid":{"rendered":"https:\/\/www.europesays.com\/ch\/22875\/"},"modified":"2026-03-02T11:04:21","modified_gmt":"2026-03-02T11:04:21","slug":"still-no-scare-for-ohtuvayre-roche-il-33-copd-data-mixed","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ch\/22875\/","title":{"rendered":"Still no scare for Ohtuvayre: Roche IL-33 COPD data mixed"},"content":{"rendered":"<p>The fate of IL-33-targeting astegolimab will be determined by talks with regulators, after Roche AG\u2019s Genentech unit rolled out mixed results from a pair of studies testing the compound vs. placebo on top of standard-of-care (SOC) maintenance therapy in subjects with moderate to very severe chronic obstructive pulmonary disease (COPD).<\/p>\n<p><a class=\"topic\" href=\"https:\/\/www.bioworld.com\/topics\/84-bioworld\" rel=\"nofollow noopener\" target=\"_blank\">BioWorld<\/a> <a class=\"topic\" href=\"https:\/\/www.bioworld.com\/topics\/153-clinical\" rel=\"nofollow noopener\" target=\"_blank\">Clinical<\/a> <a class=\"topic\" href=\"https:\/\/www.bioworld.com\/topics\/263-respiratory\" rel=\"nofollow noopener\" target=\"_blank\">Respiratory<\/a> <a class=\"topic\" href=\"https:\/\/www.bioworld.com\/topics\/282-monoclonal-antibody\" rel=\"nofollow noopener\" target=\"_blank\">Monoclonal antibody<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"The fate of IL-33-targeting astegolimab will be determined by talks with regulators, after Roche AG\u2019s Genentech unit rolled&hellip;\n","protected":false},"author":2,"featured_media":22876,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[124],"tags":[14715,3780,8086,14710,8092,14711,14712,8087,14713,14714,14717,14716,134,4178],"class_list":["post-22875","post","type-post","status-publish","format-standard","has-post-thumbnail","category-roche","tag-annualized-exacerbation-rate","tag-astegolimab","tag-bioworld","tag-chronic-obstructive-pulmonary-disease","tag-clinical","tag-copd","tag-ensifentrine","tag-genentech-inc","tag-il-33","tag-itepekimab","tag-monoclonal-antibody","tag-respiratory","tag-roche","tag-roche-ag"],"share_on_mastodon":{"url":"","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts\/22875","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/comments?post=22875"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts\/22875\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/media\/22876"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/media?parent=22875"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/categories?post=22875"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/tags?post=22875"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}