{"id":81122,"date":"2026-06-11T01:23:28","date_gmt":"2026-06-11T01:23:28","guid":{"rendered":"https:\/\/www.europesays.com\/ch\/81122\/"},"modified":"2026-06-11T01:23:28","modified_gmt":"2026-06-11T01:23:28","slug":"jpm25-roche-has-10b-ma-firepower-a-year-pharma-ceo-says","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/ch\/81122\/","title":{"rendered":"JPM25: Roche has $10B M&#038;A firepower a year, pharma CEO says"},"content":{"rendered":"<p>Roche has about $10 billion in M&amp;A firepower it can deploy every year, but it\u2019s \u201cnot just going to spend money,\u201d the company\u2019s pharma CEO Teresa Graham said at the J.P. Morgan Healthcare Conference.<\/p>\n<p>Roche is fully ready to deploy the money \u201cif and when we find transformative assets that are either complementary to our portfolio or, again, change the game in important diseases outside of those focus areas,\u201d Graham said Monday.<\/p>\n<p>The Swiss pharma didn\u2019t spend that much on business development last year, J.P. Morgan analyst Richard Vosser noted during the Q&amp;A session of Graham\u2019s presentation.<\/p>\n<p>Last fall, Roche unveiled a new pharma strategy, placing a focus on the five therapeutic areas of neurology, oncology\/hematology, immunology, ophthalmology and CVRM (cardiovascular renal metabolic).<\/p>\n<p>Some of Roche\u2019s recent deals in these focus areas include an <a href=\"https:\/\/www.fiercebiotech.com\/biotech\/roche-returns-innovent-biologics-new-1b-biobucks-adc-drug-deal\" rel=\"nofollow noopener\" target=\"_blank\">antibody-drug conjugate pact<\/a> with Innovent Biologics, the <a href=\"https:\/\/www.fiercebiotech.com\/biotech\/roche-inks-15b-poseida-buyout-betting-shelf-car-ts-will-democratize-access-cell-therapies\" rel=\"nofollow noopener\" target=\"_blank\">$1.5 billion acquisition<\/a> of off-the-shelf CAR-T partner Poseida Therapeutics, the purchase of Wnt signaling-focused biotech AntlerA Therapeutics and the $850 million upfront <a href=\"https:\/\/www.fiercebiotech.com\/biotech\/genentech-inks-850m-upfront-deal-regors-cdk-inhibitors-furthering-breast-cancer-expansion\" rel=\"nofollow noopener\" target=\"_blank\">licensing<\/a> of a portfolio of CDK inhibitors from China\u2019s Regor Pharmaceuticals. As Graham noted Monday, Roche has had a strong presence in China and will continue to look for assets in the country.<\/p>\n<p>Roche wants to get in on differentiated assets with the potential to help a large number of patients around the world, Graham added.<\/p>\n<p>Roche recently <a href=\"https:\/\/www.fiercebiotech.com\/biotech\/roches-pipeline-rethink-hits-20-new-molecules-cancer-candidates-join-discard-pile\" rel=\"nofollow noopener\" target=\"_blank\">took a hard look<\/a> at its internal pipeline, a process that led the company to discontinue about 30% of its pipeline so far, according to Graham. Still, the company expects its R&amp;D spending to remain flat in 2025; while Roche will \u201ccontinue to be very disciplined\u201d in resource allocation, it will also make sure to maintain sufficient investments in its research programs, the exec said.<\/p>\n<p>\u201cAs we\u2019ve culled so many things out of our portfolio, we have freed up a lot of oxygen to actually invest in new programs that may be internal or external,\u201d the Roche exec said.<\/p>\n<p>According to Graham, Roche&#8217;s late-stage program will look \u201cmaterially different\u201d in 2026 than it is today; about 18 programs may enter late-stage testing or graduate from that phase in the next 18 months.<\/p>\n<p>But, as is always the reality with drug development, not all Roche candidates, including those in-licensed, may succeed as planned.<\/p>\n<p>During Monday\u2019s presentation, Graham said Roche is not giving up on its Prothena-partnered prasinezumab in Parkinson\u2019s disease despite a phase 2b flop disclosed in December. While the PAVODA trial\u00a0<a href=\"https:\/\/www.fiercebiotech.com\/biotech\/roche-reports-failure-prothena-partnered-parkinsons-prospect-phase-2b-highlights-positives\" target=\"_blank\" rel=\"nofollow noopener\">missed its primary endpoint<\/a>\u00a0of time to confirmed motor progression, Roche has noted a more pronounced effect for the anti-alpha-synuclein antibody in levodopa-pretreated patients.<\/p>\n<p>\u201cGiven the high level of unmet need for these patients, we decided that the important thing to do is to let the [open-label extension] data mature a little bit longer before we actually take a decision on where we wanted to head\u201d with prasinezumab, Graham said during her presentation.<\/p>\n<p>Roche wants to thoroughly evaluate the results and make a data-driven decision. The company will be able to share more later this year, Graham said.<\/p>\n","protected":false},"excerpt":{"rendered":"Roche has about $10 billion in M&amp;A firepower it can deploy every year, but it\u2019s \u201cnot just going&hellip;\n","protected":false},"author":2,"featured_media":81123,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[124],"tags":[1115,3772,9275,1360,41976,2541,3343,134,2050],"class_list":["post-81122","post","type-post","status-publish","format-standard","has-post-thumbnail","category-roche","tag-biotech","tag-deals","tag-fierce-biotech-homepage","tag-genentech","tag-jpm-2025","tag-ma","tag-mergers-and-acquisitions","tag-roche","tag-teresa-graham"],"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@ch\/116728863575069981","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts\/81122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/comments?post=81122"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/posts\/81122\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/media\/81123"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/media?parent=81122"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/categories?post=81122"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ch\/wp-json\/wp\/v2\/tags?post=81122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}