{"id":197016,"date":"2026-08-31T08:19:18","date_gmt":"2026-08-31T08:19:18","guid":{"rendered":"https:\/\/www.europesays.com\/cz\/197016\/"},"modified":"2026-08-31T08:19:18","modified_gmt":"2026-08-31T08:19:18","slug":"nechrani-jen-pred-infekci-ctyri-ockovani-ktera-snizuji-riziko-demence-v-pozdejsim-veku","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/cz\/197016\/","title":{"rendered":"Nechr\u00e1n\u00ed jen p\u0159ed infekc\u00ed. \u010cty\u0159i o\u010dkov\u00e1n\u00ed, kter\u00e1 sni\u017euj\u00ed riziko demence v\u00a0pozd\u011bj\u0161\u00edm v\u011bku"},"content":{"rendered":"

\u201eVakc\u00edny chr\u00e1n\u00ed p\u0159ed t\u011bmito potenci\u00e1ln\u011b velmi z\u00e1va\u017en\u00fdmi infekcemi, zejm\u00e9na u\u00a0star\u0161\u00edch lid\u00ed, a\u00a0u\u017e samotn\u00e1 prevence t\u011bchto infekc\u00ed m\u00e1 obrovsk\u00fd v\u00fdznam,\u201c uvedl pro Washington Post<\/a> Avram Bukhbinder, l\u00e9ka\u0159 v\u00a0reziden\u010dn\u00edm programu v\u00a0Massachusetts General Hospital v\u00a0Bostonu, kter\u00fd se zab\u00fdval v\u00fdzkumem vakc\u00edn a\u00a0rizika demence.<\/p>\n

\u201eZd\u00e1 se, \u017ee vakc\u00edny maj\u00ed i\u00a0ur\u010dit\u00fd dal\u0161\u00ed p\u0159\u00ednos, a\u00a0v kone\u010dn\u00e9m d\u016fsledku je to dal\u0161\u00ed p\u0159esv\u011bd\u010div\u00fd d\u016fvod, pro\u010d se nechat o\u010dkovat,\u201c uvedl. <\/p>\n

Studie zjistily, \u017ee mnoho vakc\u00edn m\u016f\u017ee b\u00fdt spojov\u00e1no s\u00a0ni\u017e\u0161\u00edm rizikem demence\u00a0\u2013 zde jsou \u010dty\u0159i nejb\u011b\u017en\u011bj\u0161\u00ed, u\u00a0nich\u017e jsou souvislosti nejv\u00fdrazn\u011bj\u0161\u00ed.<\/p>\n

<\/a>O\u010dkov\u00e1n\u00ed proti ch\u0159ipce<\/p>\n

Ch\u0159ipka a\u00a0z\u00e1pal plic\u00a0\u2013 kter\u00fd m\u016f\u017ee b\u00fdt komplikac\u00ed ch\u0159ipky\u00a0\u2013 jsou podle studie<\/a> z\u00a0roku 2023\u00a0spojov\u00e1ny s\u00a0p\u011bti neurodegenerativn\u00edmi onemocn\u011bn\u00edmi, v\u010detn\u011b demence a\u00a0Parkinsonovy nemoci. Studie analyzovala data z\u00a0biobanky od v\u00edce ne\u017e 400\u00a0000\u00a0lid\u00ed.<\/p>\n

\u201eNev\u00edm, kolikr\u00e1t v\u00a0dosp\u011blosti sl\u00fdch\u00e1me: \u201aM\u016fj bl\u00edzk\u00fd dostal ch\u0159ipku, t\u00fdden nebo dva byl v\u00a0nemocnici a\u00a0u\u017e nikdy nebyl stejn\u00fd. Od t\u00e9 chv\u00edle se jeho stav rychle zhor\u0161oval,\u2018\u201c \u0159ekl Bukhbinder. <\/p>\n

Mnoho studi\u00ed podle n\u011bj zjistilo, \u017ee o\u010dkov\u00e1n\u00ed proti ch\u0159ipce je spojov\u00e1no s\u00a0ni\u017e\u0161\u00edm rizikem vzniku demence v\u00a0n\u00e1sleduj\u00edc\u00edch letech. Ve v\u00fdzkumu<\/a> z\u00a0roku 2022\u00a0Bukhbinder a\u00a0jeho kolegov\u00e9 z\u00a0University of Texas Health Science Center v\u00a0Houstonu analyzovali rozs\u00e1hlou zdravotn\u00ed datab\u00e1zi s\u00a0\u00fadaji o\u00a0v\u00edce ne\u017e 1,8\u00a0milionu dosp\u011bl\u00fdch ve v\u011bku 65\u00a0let a\u00a0v\u00edce.<\/p>\n

Zjistili, \u017ee lid\u00e9, kte\u0159\u00ed dostali alespo\u0148 jednu d\u00e1vku vakc\u00edny proti ch\u0159ipce, m\u011bli b\u011bhem n\u00e1sleduj\u00edc\u00edch \u010dty\u0159 let o\u00a040\u00a0procent ni\u017e\u0161\u00ed pravd\u011bpodobnost, \u017ee se u\u00a0nich rozvine Alzheimerova choroba\u00a0\u2013 nej\u010dast\u011bj\u0161\u00ed forma demence. <\/p>\n

O\u010dkov\u00e1n\u00ed proti ch\u0159ipce bylo tak\u00e9 spojeno se 17procentn\u00edm sn\u00ed\u017een\u00edm rizika demence ve studii<\/a> z\u00a0roku 2024, kter\u00e9 se z\u00fa\u010dastnilo v\u00edce ne\u017e 70\u00a0000\u00a0lid\u00ed. <\/p>\n

<\/a>O\u010dkov\u00e1n\u00ed proti p\u00e1sov\u00e9mu oparu<\/p>\n

O\u010dkov\u00e1n\u00ed proti p\u00e1sov\u00e9mu oparu m\u00e1 zat\u00edm nejsiln\u011bj\u0161\u00ed d\u016fkazy o\u00a0tom, \u017ee m\u016f\u017ee sni\u017eovat riziko demence. V\u00fdsledky star\u0161\u00edch studi\u00ed v\u00a0posledn\u00edch dvou letech potvrdilo n\u011bkolik rozs\u00e1hl\u00fdch v\u00fdzkum\u016f. <\/p>\n

V jedn\u00e9 studii<\/a> z\u00a0roku 2025\u00a0v\u011bdci sledovali v\u00edce ne\u017e 280\u00a0000\u00a0dosp\u011bl\u00fdch ve Walesu a\u00a0zjistili, \u017ee o\u010dkov\u00e1n\u00ed proti p\u00e1sov\u00e9mu oparu bylo spojeno s\u00a0o 20\u00a0procent ni\u017e\u0161\u00edm rizikem demence b\u011bhem sedmilet\u00e9ho obdob\u00ed. <\/p>\n

\u201eMohou existovat i\u00a0dal\u0161\u00ed potenci\u00e1ln\u00ed p\u0159\u00ednosy, kter\u00e9 p\u0159esahuj\u00ed ochranu, ji\u017e vakc\u00edna poskytuje proti konkr\u00e9tn\u00edmu onemocn\u011bn\u00ed,\u201c uvedl Pascal Geldsetzer, docent medic\u00edny na Stanford University School of Medicine a\u00a0hlavn\u00ed autor studie. \u201eJe to tedy dal\u0161\u00ed d\u016fvod, pro\u010d se nechat o\u010dkovat.\u201c<\/p>\n

Dal\u0161\u00ed studie<\/a>, kter\u00e1 se zab\u00fdvala v\u00edce ne\u017e 100\u00a0000\u00a0pacienty v\u00a0Austr\u00e1lii, podobn\u011b zjistila, \u017ee o\u010dkov\u00e1n\u00ed proti p\u00e1sov\u00e9mu oparu bylo spojeno s\u00a0ni\u017e\u0161\u00edm rizikem demence. <\/p>\n

<\/a>O\u010dkov\u00e1n\u00ed proti RSV<\/p>\n

Respira\u010dn\u00ed syncyti\u00e1ln\u00ed virus neboli RSV je b\u011b\u017en\u00fd virus d\u00fdchac\u00edch cest, kter\u00fd u\u00a0v\u011bt\u0161iny lid\u00ed zp\u016fsobuje m\u00edrn\u00e9 p\u0159\u00edznaky podobn\u00e9 nachlazen\u00ed, u\u00a0d\u011bt\u00ed a\u00a0dosp\u011bl\u00fdch ve v\u011bku 65\u00a0let a\u00a0v\u00edce v\u0161ak m\u016f\u017ee vyvolat z\u00e1va\u017en\u00e9 infekce. <\/p>\n

Ned\u00e1vn\u00e1 studie<\/a>, kter\u00e1 sledovala v\u00edce ne\u017e 430\u00a0000\u00a0lid\u00ed, zjistila, \u017ee o\u010dkov\u00e1n\u00ed proti RSV (stejn\u011b jako o\u010dkov\u00e1n\u00ed proti p\u00e1sov\u00e9mu oparu) bylo b\u011bhem 18\u00a0m\u011bs\u00edc\u016f spojeno s\u00a0ni\u017e\u0161\u00edm rizikem demence ve srovn\u00e1n\u00ed s\u00a0lidmi, kte\u0159\u00ed dostali vakc\u00ednu proti ch\u0159ipce.<\/p>\n

O\u010dkov\u00e1n\u00ed Tdap <\/p>\n

N\u011bkolik studi\u00ed uv\u00e1d\u00ed, \u017ee vakc\u00edna proti tetanu, z\u00e1\u0161krtu a\u00a0\u010dern\u00e9mu ka\u0161li (pertusi), ozna\u010dovan\u00e1 jako Tdap, je spojov\u00e1na s\u00a0ni\u017e\u0161\u00edm rizikem demence. <\/p>\n

Studie<\/a> z\u00a0roku 2021, kter\u00e1 zahrnovala v\u00edce ne\u017e 200\u00a0000\u00a0pacient\u016f, zjistila, \u017ee star\u0161\u00ed dosp\u011bl\u00ed, kte\u0159\u00ed dostali vakc\u00ednu proti p\u00e1sov\u00e9mu oparu i\u00a0vakc\u00ednu Tdap, m\u011bli je\u0161t\u011b ni\u017e\u0161\u00ed riziko demence ve srovn\u00e1n\u00ed s\u00a0t\u011bmi, kte\u0159\u00ed dostali pouze jednu z\u00a0t\u011bchto vakc\u00edn.<\/p>\n

<\/a>Jak mohou vakc\u00edny sni\u017eovat riziko demence<\/p>\n

V\u00fdzkumy<\/a> uk\u00e1zaly, \u017ee z\u00e1va\u017en\u00e9 infekce, v\u010detn\u011b ch\u0159ipky, herpetick\u00fdch infekc\u00ed a\u00a0infekc\u00ed d\u00fdchac\u00edch cest, jsou spojeny s\u00a0urychlen\u00fdm \u00fabytkem mozkov\u00e9 tk\u00e1n\u011b a\u00a0zv\u00fd\u0161en\u00fdm rizikem demence v\u00a0n\u00e1sleduj\u00edc\u00edch letech. <\/p>\n

\u201eDomn\u00edv\u00e1me se, \u017ee k\u00a0tomu pravd\u011bpodobn\u011b p\u0159isp\u00edv\u00e1 nekontrolovan\u00fd syst\u00e9mov\u00fd z\u00e1n\u011bt,\u201c uvedl Bukhbinder. \u201eA je velmi pravd\u011bpodobn\u00e9, \u017ee tito lid\u00e9 u\u017e m\u011bli z\u00e1kladn\u00ed patologick\u00e9 zm\u011bny spojen\u00e9 s\u00a0Alzheimerovou chorobou nebo jinou formou demence, ale pr\u00e1v\u011b z\u00e1n\u011bt je p\u0159ivedl do stavu, kdy se jejich stav v\u00fdrazn\u011b zhor\u0161il.\u201c <\/p>\n

Geldsetzer dodal, \u017ee virus varicella-zoster, kter\u00fd zp\u016fsobuje p\u00e1sov\u00fd opar, m\u00e1 nejz\u0159eteln\u011bj\u0161\u00ed biologickou souvislost s\u00a0rizikem demence, proto\u017ee v\u00a0nervov\u00e9m syst\u00e9mu p\u0159etrv\u00e1v\u00e1 v\u00a0neaktivn\u00edm stavu a\u00a0m\u016f\u017ee p\u0159\u00edmo ovliv\u0148ovat mozek. O\u010dkov\u00e1n\u00ed proti plan\u00fdm ne\u0161tovic\u00edm v\u00a0d\u011btstv\u00ed m\u016f\u017ee zabr\u00e1nit tomu, aby se virus v\u00a0organismu v\u016fbec uchytil. <\/p>\n

P\u0159esto\u017ee jsou r\u016fzn\u00e9 vakc\u00edny spojov\u00e1ny s\u00a0ni\u017e\u0161\u00edm rizikem demence, v\u00fdzkumy maj\u00ed sv\u00e1 omezen\u00ed. Jedn\u00e1 se o\u00a0statistickou souvislost, nikoli o\u00a0prok\u00e1zanou p\u0159\u00ed\u010dinnou souvislost, proto\u017ee lid\u00e9, kte\u0159\u00ed se nech\u00e1vaj\u00ed o\u010dkovat, se mohou v\u00a0n\u011bkter\u00fdch ohledech li\u0161it od t\u011bch, kte\u0159\u00ed o\u010dkov\u00e1n\u00ed nepodstupuj\u00ed. <\/p>\n

Nap\u0159\u00edklad m\u016f\u017ee platit, \u017ee \u201elid\u00e9, kte\u0159\u00ed jsou v\u00a0pr\u016fm\u011bru v\u00edce zam\u011b\u0159en\u00ed na sv\u00e9 zdrav\u00ed a\u00a0maj\u00ed zdrav\u011bj\u0161\u00ed \u017eivotn\u00ed n\u00e1vyky, jsou pr\u00e1v\u011b ti, kte\u0159\u00ed se rozhodnou nechat o\u010dkovat,\u201c uvedl Geldsetzer. P\u0159esto\u017ee se v\u011bdci sna\u017e\u00ed tyto matouc\u00ed faktory zohlednit, nen\u00ed mo\u017en\u00e9 zcela odfiltrovat rozd\u00edly ve zdravotn\u00edm chov\u00e1n\u00ed, kter\u00e9 souvisej\u00ed s\u00a0rizikem demence.<\/p>\n

<\/a><\/p>\n

Studie<\/a> v\u0161ak nazna\u010duj\u00ed siln\u011bj\u0161\u00ed souvislost mezi o\u010dkov\u00e1n\u00edm proti p\u00e1sov\u00e9mu oparu a\u00a0sn\u00ed\u017een\u00edm rizika demence. Tento v\u00fdzkum vyu\u017e\u00edv\u00e1 takzvan\u00e9 \u201ep\u0159irozen\u00e9 experimenty\u201c, kter\u00e9 vznikly d\u00edky p\u0159esn\u011b stanoven\u00fdm dat\u016fm, kdy vl\u00e1dy Walesu a\u00a0Austr\u00e1lie ur\u010dily, kdo m\u00e1 na o\u010dkov\u00e1n\u00ed proti p\u00e1sov\u00e9mu oparu n\u00e1rok. <\/p>\n

Lid\u00e9 narozen\u00ed t\u011bsn\u011b p\u0159ed a\u00a0t\u011bsn\u011b po stanoven\u00e9m datu se pravd\u011bpodobn\u011b nijak z\u00e1sadn\u011b neli\u0161\u00ed, a\u00a0lze je proto p\u0159\u00edmo porovn\u00e1vat. A\u00a0kdy\u017e je v\u011bdci porovnali, zjistili, \u017ee lid\u00e9, kte\u0159\u00ed dostali vakc\u00ednu proti p\u00e1sov\u00e9mu oparu, m\u011bli ni\u017e\u0161\u00ed riziko demence, uvedl Geldsetzer. Ten byl spoluautorem studi\u00ed z\u00a0Walesu a\u00a0Austr\u00e1lie a\u00a0v sou\u010dasnosti z\u00edsk\u00e1v\u00e1 prost\u0159edky na financov\u00e1n\u00ed randomizovan\u00e9 kontrolovan\u00e9 studie.<\/p>\n

Existuj\u00ed dv\u011b hlavn\u00ed biologick\u00e9 hypot\u00e9zy, kter\u00e9 vysv\u011btluj\u00ed, jak mohou vakc\u00edny souviset s\u00a0ni\u017e\u0161\u00edm rizikem demence. Vakc\u00edny mohou sni\u017eovat riziko onemocn\u011bn\u00ed a\u00a0z\u00e1va\u017enost infekc\u00ed, kter\u00e9 byly spojeny se zv\u00fd\u0161en\u00fdm rizikem demence. \u201eJsem p\u0159esv\u011bd\u010den\u00fd, \u017ee to je sou\u010d\u00e1st cel\u00e9ho p\u0159\u00edb\u011bhu, ale rozhodn\u011b to nen\u00ed cel\u00fd p\u0159\u00edb\u011bh,\u201c uvedl Bukhbinder. <\/p>\n

Dal\u0161\u00ed, vz\u00e1jemn\u011b se nevylu\u010duj\u00edc\u00ed mo\u017enost\u00ed je, \u017ee samotn\u00e1 vakc\u00edna m\u016f\u017ee p\u0159\u00edzniv\u00fdm zp\u016fsobem aktivovat imunitn\u00ed syst\u00e9m. \u201eO\u010dkov\u00e1n\u00ed m\u016f\u017ee imunitn\u00ed reakci zdokonalovat nebo usm\u011br\u0148ovat,\u201c \u0159ekl Bukhbinder. \u201eExistuj\u00ed p\u0159esv\u011bd\u010div\u00e9 d\u016fkazy, \u017ee to, co se d\u011bje mimo mozek, skute\u010dn\u011b velmi v\u00fdrazn\u011b ovliv\u0148uje to, co se d\u011bje uvnit\u0159 mozku,\u201c dodal. <\/p>\n

<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"\u201eVakc\u00edny chr\u00e1n\u00ed p\u0159ed t\u011bmito potenci\u00e1ln\u011b velmi z\u00e1va\u017en\u00fdmi infekcemi, zejm\u00e9na u\u00a0star\u0161\u00edch lid\u00ed, a\u00a0u\u017e samotn\u00e1 prevence t\u011bchto infekc\u00ed m\u00e1 obrovsk\u00fd…\n","protected":false},"author":2,"featured_media":197017,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[10],"tags":[9387,17,21,16,2192,18,19,22,11509,16280,20],"class_list":["post-197016","post","type-post","status-publish","format-standard","has-post-thumbnail","category-zpravy","tag-demence","tag-headlines","tag-hlavni-udalosti","tag-news","tag-ockovani","tag-top-news","tag-top-stories","tag-udalosti-dne","tag-vakcina","tag-vakcinace","tag-zpravy"],"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@cz\/117189146698117212","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/posts\/197016","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/comments?post=197016"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/posts\/197016\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/media\/197017"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/media?parent=197016"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/categories?post=197016"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/cz\/wp-json\/wp\/v2\/tags?post=197016"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}