The airline confirmed to the public broadcaster that flights between Vilnius Airport and Finland’s Turku Airport will cease from 17 September.
Until then, services will operate three times a week, on Tuesdays, Thursdays and Saturdays.
Wizz Air said it continuously monitors route performance to meet passenger demand and offer competitive prices on its most popular connections.
The network is regularly optimised based on overall performance assessments, it added.
On 7 June, Wizz Air launched direct flights from Vilnius, the capital of Lithuania, to Podgorica, the capital of Montenegro after starting a service between Vilnius and Gdansk, Poland in May.
In September, the airline will offer flights from the Lithuanian capital to Prague, the Czech Republic.
The Hungarian airline and Lithuanian Airports (LTOU) have been cooperating for 15 years.