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A Norwegian<\/a> man just became the 10th person<\/a> ever cured of HIV,<\/a> and the story behind his recovery is nothing short of a medical miracle. After living with the virus for over a decade, he received a stem cell transplant from his brother to treat a rare blood cancer.<\/a> What doctors<\/a> didn\u2019t expect was that the transplant would also wipe out his HIV \u2014 thanks to a genetic mutation in his brother\u2019s cells that made them resistant to the virus.<\/p>\n According to the NY Post,<\/a> the procedure took place at Oslo University Hospital,<\/a> where researchers<\/a> kept a close eye on the patient, now known in medical circles as the \u201cOslo patient.\u201d Five years and countless tests later, the results are in. The man shows no signs of active HIV, making him the latest in a tiny group of people who\u2019ve achieved long-term remission from the virus.\u00a0<\/p>\n As of 2024, nearly 41 million people worldwide are living with HIV,<\/a> according to the World Health Organization,<\/a> so every breakthrough like this one is a big deal. The Oslo patient\u2019s case was detailed in the journal Nature Microbiology.<\/a> Marius Tr\u00f8seid, one of the authors, said the patient \u201cfeels like he has won the lottery twice \u2026 He was cured of his bone marrow disease, which could be fatal, and he\u2019s also now cured of HIV, most likely.\u201d\u00a0<\/p>\n This is an incredible outcome for a treatment that wasn\u2019t even designed to target HIV <\/p>\n The drugs used to manage HIV today work by keeping the virus from replicating, but they don\u2019t eliminate it. Stop the medication, and the virus usually comes roaring back. But in this case, the brother\u2019s stem cells did something far more dramatic. They didn\u2019t just resist HIV \u2014 they removed a key receptor in the patient\u2019s white blood cells that the virus needed to infect the immune system. Without that receptor, HIV had nowhere to go.<\/p>\n The transplant itself was a gamble.<\/a> Stem cell transplants are often called \u201crisky reboots of the immune system\u201d for a reason. They can lead to fatal infections, and up to 20% of patients who survive the procedure die within a year. The Oslo patient wasn\u2019t immune to complications either. He developed graft-versus-host disease, a serious condition where the donated cells attack the recipient\u2019s body. But in the end, the HIV-resistant stem cells won out.\u00a0<\/p>\n ?Big Hope in HIV Research! \u2014 EngineerKnow (@engineer_know) April 14, 2026<\/a> <\/p>\n Over time, his immune system\u2019s T cells \u2014 usually hijacked by HIV \u2014 stopped acting like they were under attack. Two years after the transplant, he was able to stop taking his HIV medication entirely. Four years in, doctors found no traces of functional HIV DNA in his body. His most recent check-up, five years after the procedure, confirmed the same result.<\/p>\n However, doctors are cautious about calling this an outright cure <\/p>\n The process the Oslo patient went through is nearly impossible to replicate on a large scale. The risks are too high, and the logistics too complex. But that doesn\u2019t mean the findings aren\u2019t valuable. The researchers behind the study are hopeful that this case, along with others like it, will help guide future research into more accessible and replicable cure methods.\u00a0<\/p>\n In their words, \u201cThis and other studies on HIV cure enhance our understanding of HIV pathology, molecular mechanisms and predictive biomarkers that may be of broader interest\u201d beyond just transplant patients. So, where did this HIV-resistant mutation come from? According to Galv News,<\/a> it turns out the CCR5 delta 32 mutation, which makes cells resistant to HIV, has been floating around in human genomes for thousands of years.\u00a0<\/p>\n Up to 16% of people with European ancestry carry it, but its origins are a mystery. Researchers digging through the 1,000 Genomes Project \u2013 an international effort to catalog human genetic variation \u2013 found the mutation in 2,504 modern human genomes. They also traced it back to ancient DNA, pinpointing its emergence to a person who lived near the Black Sea sometime between 6,700 and 9,000 years ago. That\u2019s when early farmers were migrating into Europe.<\/p>\n The mutation became much more common between 8,000 and 2,000 years ago, which suggests it gave people some kind of advantage back then \u2013 but it wasn\u2019t HIV resistance. That virus didn\u2019t jump from chimpanzees to humans until the early 20th century. So what was the benefit? Scientists aren\u2019t entirely sure.\u00a0<\/p>\n The research on HIV treatments is continuing and has a long way to go <\/p>\n One theory is that the mutation might have helped dampen the immune response just enough to protect the body without causing damage. An overactive immune system can be just as dangerous as an underactive one. CCR5, the protein affected by the mutation, helps immune cells respond to signals called chemokines, which coordinate the body\u2019s defense against infections. It also plays a role in guiding immune cells to sites of inflammation.<\/p>\n Amazing breakthrough! <\/p>\n This is the “Oslo patient” \u2013 a 63-year-old Norwegian man who achieved long-term HIV remission after a stem cell transplant from his brother (who carries the rare CCR5\u039432\/\u039432 mutation that blocks HIV entry). <\/p>\n The transplant was done to treat\u2026<\/p>\n \u2014 The Lolgic (@theLolgic) April 14, 2026<\/a> <\/p>\n As ancient humans transitioned from nomadic hunter-gatherer lifestyles to farming communities, the diseases they faced changed too. Living in close quarters and storing food would have exposed them to new pathogens. The CCR5 delta 32 mutation might have helped them survive.\u00a0<\/p>\n What we do know is that it\u2019s a lucky break for anyone exposed to HIV today. People with this mutation can\u2019t be infected by the virus, which means they\u2019re automatically protected from AIDS. The Oslo patient\u2019s story is a reminder of how much we still have to learn about the human body and the viruses that plague it.\u00a0<\/p>\n Have a tip we should know? [email\u00a0protected]<\/a><\/p>\n \t
A 63-year-old Norwegian man known as the “Oslo Patient” has achieved long-term remission from HIV \u2014 possibly even a functional cure \u2014 after a stem cell transplant from his brother.
Here’s what makes this case special:
He received a bone marrow\/stem\u2026 pic.twitter.com\/6xoAVcl8as<\/a><\/p>\n![\"Image](\"https:\/\/www.europesays.com\/dk\/wp-content\/uploads\/2026\/04\/Terrina-TMS.png\")
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