Kohvis leiduvad \u00fchendid v\u00f5ivad aktiveerida rakkudes retseptori, mis aitab organismil reageerida stressile, p\u00f5letikule ja koekahjustustele. Avastus v\u00f5ib osaliselt selgitada, miks kohvijoomist on varasemates uuringutes seostatud v\u00e4iksema krooniliste haiguste riski ja pikema elueaga.<\/p>\n
USA Texase A&M \u00fclikooli teadlased uurisid NR4A1-nimelist tuumaretseptorit, mis reguleerib geenide aktiivsust ning osaleb muu hulgas ainevahetuses, p\u00f5letikureaktsioonides ja kudede taastumises.<\/p>\n
Laborikatsetes leidsid teadlased, et kohv ja mitmed selles sisalduvad pol\u00fcfenoolsed \u00fchendid, n\u00e4iteks kohvhape, suudavad NR4A1-ga seonduda ja selle aktiivsust muuta. Kui teadlased retseptori katserakkudest eemaldasid, kadusid ka mitmed kohvi\u00fchenditega seostatud kaitsvad m\u00f5jud.<\/p>\n
\u00dcllatuslikult ei paistnud peamine toime tulevat kofeiinist. Kuigi ka kofeiin seondus retseptoriga, avaldasid teised kohvis leiduvad taimsed \u00fchendid katsetes m\u00e4rksa tugevamat m\u00f5ju. See v\u00f5ib aidata selgitada, miks ka kofeiinivaba kohvi on rahvastikuuuringutes seostatud tervisekasuga.<\/p>\n
Tulemused ei t\u00f5esta siiski, et kohvi joomine aeglustaks inimestel vananemist v\u00f5i raviks haigusi. Katsed tehti peamiselt raku- ja laborimudelites ning teadlaste hinnangul on NR4A1 t\u00f5en\u00e4oliselt ainult \u00fcks paljudest mehhanismidest, mille kaudu kohv organismi m\u00f5jutab.<\/p>\n
Uuring <\/a>ilmus teadusajakirjas Nutrients. Uurimisr\u00fchm loodab, et NR4A1 toimimise parem m\u00f5istmine v\u00f5ib tulevikus aidata v\u00e4lja t\u00f6\u00f6tada raviaineid, mis aktiveerivad sama retseptorit kohvi looduslikest \u00fchenditest t\u00f5husamalt.<\/p>\n Kuidas see lugu Sind end tundma pani? Saada Kommenteeri <\/a> Loe kommentaare (3)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Kohvis leiduvad \u00fchendid v\u00f5ivad aktiveerida rakkudes retseptori, mis aitab organismil reageerida stressile, p\u00f5letikule ja koekahjustustele. Avastus v\u00f5ib osaliselt…\n","protected":false},"author":2,"featured_media":233129,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_share_on_mastodon":"0"},"categories":[80],"tags":[26,27,37,33,35,34,36,31,32,21,8041,28,29,95,19,25,23,24,22,20,30,92,93,94],"class_list":["post-233128","post","type-post","status-publish","format-standard","has-post-thumbnail","category-maailm","tag-breaking-news","tag-breakingnews","tag-ee","tag-eesti","tag-eesti-keel","tag-estonia","tag-estonian","tag-featured-news","tag-featurednews","tag-headlines","tag-kohv","tag-latest-news","tag-latestnews","tag-maailm","tag-news","tag-populaarseimad-lood","tag-top-stories","tag-topstories","tag-uldised-uudised","tag-uudised","tag-viimased-uudised","tag-world","tag-world-news","tag-worldnews"],"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@ee\/116957455524900626","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/posts\/233128","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/comments?post=233128"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/posts\/233128\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/media\/233129"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/media?parent=233128"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/categories?post=233128"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/ee\/wp-json\/wp\/v2\/tags?post=233128"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}