{"id":16072,"date":"2025-04-10T23:22:18","date_gmt":"2025-04-10T23:22:18","guid":{"rendered":"https:\/\/www.europesays.com\/fr\/16072\/"},"modified":"2025-04-10T23:22:18","modified_gmt":"2025-04-10T23:22:18","slug":"un-medicament-offre-une-premiere-piste-prometteuse-contre-laddiction-a-la-cocaine","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/fr\/16072\/","title":{"rendered":"Un m\u00e9dicament offre une premi\u00e8re piste prometteuse contre l\u2019addiction \u00e0 la coca\u00efne"},"content":{"rendered":"

Par Delphine Chayet<\/a><\/p>\n

\n Publi\u00e9
\n le 9 avril 2025 \u00e0 06h00,
\n mis \u00e0 jour le 9 avril 2025 \u00e0 10h22<\/p>\n

La coca\u00efne serait \u00e0 l\u2019origine de 10 000 hospitalisations par an, et de complications m\u00e9dicales dont la gravit\u00e9 et la fr\u00e9quence augmentent.
\n Ksinan Peter \/ pe3check – stock.adobe.com<\/p>\n

D\u00c9CRYPTAGE<\/strong> – Une mol\u00e9cule d\u00e9j\u00e0 test\u00e9e dans d\u2019autres pathologies a permis, dans un petit essai clinique, de r\u00e9duire la consommation de personnes d\u00e9pendantes.<\/p>\n

Alors que\u00a0la consommation de coca\u00efne<\/a>\u00a0atteint des niveaux records en France, il n\u2019existe aucun m\u00e9dicament approuv\u00e9 pour soigner cette addiction. Selon l\u2019Observatoire fran\u00e7ais des drogues et de la toxicomanie, plus d\u2019un million de personnes ont consomm\u00e9 ce psychostimulant au moins une fois en 2023 \u2013deux fois plus que l\u2019ann\u00e9e pr\u00e9c\u00e9dente.\u00a0La coca\u00efne<\/a>\u00a0serait \u00e0 l\u2019origine de 10\u00a0000 hospitalisations par an, et de complications m\u00e9dicales dont la gravit\u00e9 et la fr\u00e9quence augmentent. Des chercheurs du laboratoire Novartis pr\u00e9sentent une piste th\u00e9rapeutique jug\u00e9e \u00ab\u00a0prometteuse\u00a0\u00bb, qu\u2019ils ont test\u00e9e pour la premi\u00e8re fois chez l\u2019\u00eatre humain.<\/p>\n

Les scientifiques ont cherch\u00e9 \u00e0 mod\u00e9rer l\u2019activit\u00e9 d\u2019un neurotransmetteur excitateur du cerveau, le glutamate, impliqu\u00e9 dans le traitement de la r\u00e9compense et de la d\u00e9pendance \u00e0 la coca\u00efne. Pour cela, expliquent-ils\u00a0dans la revue Science Translational Medicine<\/a>, ils ont utilis\u00e9 une mol\u00e9cule d\u00e9j\u00e0 connue, le mavoglurant, capable de bloquer un r\u00e9cepteur au glutamate\u2026<\/p>\n

\n Cet article est r\u00e9serv\u00e9 aux abonn\u00e9s. Il vous reste 74% \u00e0 d\u00e9couvrir.\n <\/p>\n

\"Le<\/p>\n

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\n <\/a>\n <\/p>\n","protected":false},"excerpt":{"rendered":"Par Delphine Chayet Publi\u00e9 le 9 avril 2025 \u00e0 06h00, mis \u00e0 jour le 9 avril 2025 \u00e0…\n","protected":false},"author":2,"featured_media":16073,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[237,6654,101,232,231,3993,234,228,1011,27,72,239,230,238,226,224,225,233,229,236,235,71,227],"class_list":{"0":"post-16072","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-sante","8":"tag-actualite-sur-les-maladies","9":"tag-addiction","10":"tag-cancer","11":"tag-cardiologie","12":"tag-cerveau","13":"tag-cocaine","14":"tag-diabete","15":"tag-diagnostic","16":"tag-fr","17":"tag-france","18":"tag-health","19":"tag-info-sur-les-maladies","20":"tag-infographie","21":"tag-information-sur-les-maladies","22":"tag-maladie","23":"tag-medecine","24":"tag-medicament","25":"tag-obesite","26":"tag-pathologie","27":"tag-pediatrie","28":"tag-psychiatrie","29":"tag-sante","30":"tag-traitement"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@fr\/114316243289485488","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts\/16072","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/comments?post=16072"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts\/16072\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/media\/16073"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/media?parent=16072"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/categories?post=16072"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/tags?post=16072"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}