{"id":528146,"date":"2025-11-11T23:24:17","date_gmt":"2025-11-11T23:24:17","guid":{"rendered":"https:\/\/www.europesays.com\/fr\/528146\/"},"modified":"2025-11-11T23:24:17","modified_gmt":"2025-11-11T23:24:17","slug":"la-prise-de-depakine-par-le-pere-augmente-les-risques-pour-le-developpement-du-cerveau-de-lenfant","status":"publish","type":"post","link":"https:\/\/www.europesays.com\/fr\/528146\/","title":{"rendered":"La prise de D\u00e9pakine par le p\u00e8re augmente les risques pour le d\u00e9veloppement du cerveau de l\u2019enfant"},"content":{"rendered":"

La prescription initiale de valproate et de ses d\u00e9riv\u00e9s est d\u00e9sormais r\u00e9serv\u00e9e aux neurologues, psychiatres et p\u00e9diatres pour les adolescents et les hommes susceptibles d\u2019avoir des enfants.
\n luchschen \/ luchschenF – stock.adobe.com<\/p>\n

\n La plus vaste \u00e9tude \u00e9pid\u00e9miologique men\u00e9e \u00e0 ce jour montre notamment un exc\u00e8s de risque de troubles du d\u00e9veloppement intellectuel.<\/p>\n

Le soup\u00e7on \u00e9tait suffisamment solide pour que les autorit\u00e9s sonnent l\u2019alerte d\u00e8s 2023. C\u2019est d\u00e9sormais un fait av\u00e9r\u00e9 par une \u00e9tude \u00e9pid\u00e9miologique de large ampleur\u00a0: le valproate de sodium (D\u00e9pakine et g\u00e9n\u00e9riques) peut entra\u00eener des troubles neurod\u00e9veloppementaux chez l\u2019enfant \u00e0 na\u00eetre\u00a0s\u2019il a \u00e9t\u00e9 pris par son p\u00e8re<\/a>\u00a0dans les mois pr\u00e9c\u00e9dant la conception.<\/p>\n

Les m\u00e9dicaments \u00e0 base de valproate de sodium (D\u00e9pakine, D\u00e9pakote, D\u00e9pamide, Micropakine et leurs g\u00e9n\u00e9riques) sont largement utilis\u00e9s dans le traitement de\u00a0l\u2019\u00e9pilepsie<\/a>\u00a0et des\u00a0troubles bipolaires<\/a>. En 2015, avait \u00e9clat\u00e9\u00a0une retentissante affaire<\/a>\u00a0concernant ce m\u00e9dicament\u00a0: les femmes le prenant durant la grossesse exposaient leurs enfants \u00e0 de graves risques de malformations cong\u00e9nitales et de troubles neurod\u00e9veloppementaux, dont l\u2019autisme. Un risque qui \u00e9tait connu du laboratoire et des autorit\u00e9s sanitaires, mais dont patientes et m\u00e9decins n\u2019avaient pas \u00e9t\u00e9 suffisamment inform\u00e9s,\u00a0a jug\u00e9 la justice \u00e0 plusieurs reprises<\/a>. Restait une\u2026<\/p>\n

\n Cet article est r\u00e9serv\u00e9 aux abonn\u00e9s. Il vous reste 74% \u00e0 d\u00e9couvrir.\n <\/p>\n

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\n <\/a>\n <\/p>\n","protected":false},"excerpt":{"rendered":"La prescription initiale de valproate et de ses d\u00e9riv\u00e9s est d\u00e9sormais r\u00e9serv\u00e9e aux neurologues, psychiatres et p\u00e9diatres pour…\n","protected":false},"author":2,"featured_media":528147,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[8187,41029,41026,1011,27,72,71],"class_list":{"0":"post-528146","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-sante","8":"tag-autisme","9":"tag-depakine","10":"tag-epilepsie","11":"tag-fr","12":"tag-france","13":"tag-health","14":"tag-sante"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@fr\/115533648018994893","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts\/528146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/comments?post=528146"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts\/528146\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/media\/528147"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/media?parent=528146"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/categories?post=528146"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/tags?post=528146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}