C\u2019est quoi les CAR-T cells\u00a0?<\/p>\n
Ce sont des m\u00e9dicaments fabriqu\u00e9s \u00e0 partir de cellules immunitaires, les lymphocytes T, de patients atteints de cancers du sang. Ces lymphocytes sont modifi\u00e9s g\u00e9n\u00e9tiquement pour exprimer un nouveau r\u00e9cepteur \u00e0 leur surface, nomm\u00e9 CAR (Chimeric Antigen Receptor ou r\u00e9cepteur antig\u00e9nique chim\u00e9riques) gr\u00e2ce auquel ils vont mieux cibler et d\u00e9truire les cellules tumorales. Les lymphocytes ainsi boost\u00e9s sont r\u00e9inject\u00e9s au patient.<\/p>\n
O\u00f9 en est-on \u00e0 Lyon\u00a0?<\/p>\n
Les Hospices civils de Lyon ont \u00e9t\u00e9 parmi les premiers en Europe \u00e0 traiter des patients par CAR-T cells en 2018<\/a> , au sein du service d\u2019h\u00e9matologie de Lyon sud<\/a> o\u00f9 le 500e patient a \u00e9t\u00e9 trait\u00e9 en mars\u00a02025. \u00ab\u00a0Nous sommes au coude-\u00e0-coude avec l\u2019h\u00f4pital Saint-Louis \u00e0 Paris et nous avons publi\u00e9 plus de 40 articles dans des revues prestigieuses\u00a0\u00bb, souligne le Dr Pierre Sesques, m\u00e9decin dans ce service qui traite actuellement 100 patients\/an sur un p\u00e9rim\u00e8tre allant jusqu\u2019\u00e0 Roanne, Aubenas, Annemasse, Chalon, M\u00e2con.<\/p>\n Quand… <\/p>\n","protected":false},"excerpt":{"rendered":"C\u2019est quoi les CAR-T cells\u00a0? Ce sont des m\u00e9dicaments fabriqu\u00e9s \u00e0 partir de cellules immunitaires, les lymphocytes T,…\n","protected":false},"author":2,"featured_media":78459,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1889],"tags":[1111,11,2430,2757,1777,674,1011,27,2428,2756,12,25,2429,71],"class_list":{"0":"post-78458","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-lyon","8":"tag-actu","9":"tag-actualites","10":"tag-auvergne-rhone-alpes","11":"tag-edition-lyon-villeurbanne","12":"tag-eu","13":"tag-europe","14":"tag-fr","15":"tag-france","16":"tag-lyon","17":"tag-lyon-bassin","18":"tag-news","19":"tag-republique-francaise","20":"tag-rhone","21":"tag-sante"},"share_on_mastodon":{"url":"https:\/\/pubeurope.com\/@fr\/114459161731673861","error":""},"_links":{"self":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts\/78458","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/comments?post=78458"}],"version-history":[{"count":0,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/posts\/78458\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/media\/78459"}],"wp:attachment":[{"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/media?parent=78458"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/categories?post=78458"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.europesays.com\/fr\/wp-json\/wp\/v2\/tags?post=78458"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}