• Smolen JS, Aletaha D, Barton A, Burmester GR, Emery P, Firestein GS, et al. Rheumatoid arthritis. Nat Rev Dis Primers. 2018. https://doi.org/10.1038/nrdp.2018.1.

    Article 
    PubMed 

    Google Scholar
     

  • Wajnsztajn D, Nche E, Solomon A. Corneal complications of rheumatoid arthritis. Curr Opin Allergy Clin Immunol. 2022;22(5):304–13.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Sainz de la Maza M, Foster CS, Jabbur NS, Baltatzis S. Ocular characteristics and disease associations in scleritis-associated peripheral keratopathy. Arch Ophthalmol. 2002;120(1):15–9.

  • Galor A, Thorne JE. Scleritis and peripheral ulcerative keratitis. Rheum Dis Clin North Am. 2007;33(4):835–54, vii.

  • Tauber J, Sainz de la Maza M, Hoang-Xuan T, Foster CS. An analysis of therapeutic decision making regarding immunosuppressive chemotherapy for peripheral ulcerative keratitis. Cornea. 1990;9(1):66-73.

  • Smolen JS, Breedveld FC, Burmester GR, Bykerk V, Dougados M, Emery P, et al. Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis. 2016;75(1):3–15.

    Article 
    PubMed 

    Google Scholar
     

  • Radu AF, Bungau SG. Management of rheumatoid arthritis: an overview. Cells. 2021. https://doi.org/10.3390/cells10112857.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Angelini J, Talotta R, Roncato R, Fornasier G, Barbiero G, Dal Cin L, et al. Jak-inhibitors for the treatment of rheumatoid arthritis: a focus on the present and an outlook on the future. Biomolecules. 2020. https://doi.org/10.3390/biom10071002.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kameda H, Takeuchi T, Yamaoka K, Oribe M, Kawano M, Zhou Y, et al. Efficacy and safety of upadacitinib in Japanese patients with rheumatoid arthritis (SELECT-SUNRISE): a placebo-controlled phase IIb/III study. Rheumatology (Oxford). 2020;59(11):3303–13.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kremer JM, Emery P, Camp HS, Friedman A, Wang L, Othman AA, et al. A phase IIb study of ABT-494, a selective JAK-1 inhibitor, in patients with rheumatoid arthritis and an inadequate response to anti-tumor necrosis factor therapy. Arthritis Rheumatol. 2016;68(12):2867–77.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Timlin HM, Hall HN, Foot B, Koay P. Corneal perforation from peripheral ulcerative keratopathy in patients with rheumatoid arthritis: epidemiological findings of the British Ophthalmological Surveillance Unit. Br J Ophthalmol. 2018;102(9):1298–302.

    Article 
    PubMed 

    Google Scholar
     

  • Artifoni M, Rothschild PR, Brézin A, Guillevin L, Puéchal X. Ocular inflammatory diseases associated with rheumatoid arthritis. Nat Rev Rheumatol. 2014;10(2):108–16.

    Article 
    PubMed 

    Google Scholar
     

  • Dana R, Farid M, Gupta PK, Hamrah P, Karpecki P, McCabe CM, et al. Expert consensus on the identification, diagnosis, and treatment of neurotrophic keratopathy. BMC Ophthalmol. 2021;21(1):327.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bonini S, Rama P, Olzi D, Lambiase A. Neurotrophic keratitis. Eye (Lond). 2003;17(8):989–95.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Font CS, Cortina MS. Neurotrophic keratopathy: update in diagnosis and management. Indian J Ophthalmol. 2025;73(4):483–95.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Cao Y, Zhang W, Wu J, Zhang H, Zhou H. Peripheral Ulcerative Keratitis Associated with Autoimmune Disease: Pathogenesis and Treatment. J Ophthalmol. 2017;2017:7298026.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang J, Zhang Q, Shi W, Pang Y, Li S. Peripheral ulcerative keratitis, nodular episcleritis, and pulmonary nodules as the initial signs of rheumatic arthritis: a case report. Front Immunol. 2022;13:1048889.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mehta K, Gujjar AP, Babu K. Peripheral ulcerative keratitis in a young lady with systemic lupus erythematosus post Rituximab infusion-a case report. Ocul Immunol Inflamm. 2022;30(6):1312–4.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Çakmak A, Akova Y, Yıldırım N. The complete success in refractory Mooren’s ulcer treated with Infliximab. Ocul Immunol Inflamm. 2023;31(4):682–8.

    Article 
    PubMed 

    Google Scholar
     

  • Martínez-Abad A, Piñero DP. Pellucid marginal degeneration: detection, discrimination from other corneal ectatic disorders and progression. Contact Lens Anterior Eye. 2019;42(4):341–9.

    Article 
    PubMed 

    Google Scholar
     

  • Gupta Y, Kishore A, Kumari P, Balakrishnan N, Lomi N, Gupta N, et al. Peripheral ulcerative keratitis. Surv Ophthalmol. 2021;66(6):977–98.

    Article 
    PubMed 

    Google Scholar
     

  • Bonnet I, Rousseau A, Duraffour P, Pouchot J, Nguyen CD, Gabison E, et al. Efficacy and safety of rituximab in peripheral ulcerative keratitis associated with rheumatoid arthritis. RMD Open. 2021. https://doi.org/10.1136/rmdopen-2020-001472.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kito K, Fukuda K, Kishimoto T, Yamashiro K, Yagami A. Treatment of vernal keratoconjunctivitis using Upadacitinib. JAMA Ophthalmol. 2024. https://doi.org/10.1001/jamaophthalmol.2024.1439.

    Article 
    PubMed 

    Google Scholar
     

  • Cohen F, Gabison EE, Stéphan S, Belkhir R, Nocturne G, Best AL, et al. Peripheral ulcerative keratitis in rheumatoid arthritis patients taking tocilizumab: paradoxical manifestation or insufficient efficacy? Rheumatology (Oxford). 2021;60(11):5413–8.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Xin P, Xu X, Deng C, Liu S, Wang Y, Zhou X, et al. The role of JAK/STAT signaling pathway and its inhibitors in diseases. Int Immunopharmacol. 2020;80:106210.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Banerjee S, Biehl A, Gadina M, Hasni S, Schwartz DM. Jak-stat signaling as a target for inflammatory and autoimmune diseases: current and future prospects. Drugs. 2017;77(5):521–46.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Clarke B, Yates M, Adas M, Bechman K, Galloway J. The safety of JAK-1 inhibitors. Rheumatology (Oxford). 2021;60(Suppl 2):ii24–30.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ytterberg SR, Bhatt DL, Mikuls TR, Koch GG, Fleischmann R, Rivas JL, et al. Cardiovascular and cancer risk with tofacitinib in rheumatoid arthritis. N Engl J Med. 2022;386(4):316–26.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Reich K, Teixeira HD, de Bruin-Weller M, Bieber T, Soong W, Kabashima K, et al. Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2021;397(10290):2169–81.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wu Y, Wei M, Zhang J. A real-world pharmacovigilance analysis of FDA adverse event reporting system database for upadacitinib. Front Pharmacol. 2023;14:1200254.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Choy EH. Clinical significance of Janus kinase inhibitor selectivity. Rheumatology (Oxford). 2019;58(6):953–62.

    Article 
    CAS 
    PubMed 

    Google Scholar