Eric Dane passed away today after a long battle with ALS.

Dane’s breakout role came as Dr. Mark “McSteamy” Sloan on ABC’s Grey’s Anatomy from 2006-2012, but he worked steadily through the years on TV and in films opposite the likes of Zendaya, Jennifer Aniston, Jessica Biel, Owen Wilson, Jessica Alba, Hugh Jackman and many others.

Among his many other projects through the years are Euphoria, Private Practice, The Last Ship, Charmed, Marley & Me, Countdown, X-Men: The Last Stand and Valentine’s Day.

Scroll through the gallery below for a sampling of his work on both the big and small screen.

  • GREY’S ANATOMY, 2010


    Image Credit: Adam Larkey / ABC / courtesy Everett Collection

    Eric Dane, ‘State of Love and Trust’

  • GREY’S ANATOMY, 2010


    Image Credit: Eric McCandless / ABC / courtesy Everett Collection

    Kevin McKidd, Eric Dane, Patrick Dempsey, Sara Ramirez, ‘These Arms of Mine’

  • GREY’S ANATOMY


    Image Credit: Scott Garfield/Disney General Entertainment Content via Getty Images

    Ellen Pompeo, Eric Dane “Where the Boys Are”

  • GREY’S ANATOMY, Season Seven Promo


    Image Credit: Bob D’Amico/Disney General Entertainment Content via Getty Images

    Eric Dane as Mark Sloan

  • The 33rd Annual People’s Choice Awards


    Image Credit: Albert L. Ortega/WireImage

    Eric Dane, Katherine Heigl, TR Knight, Chandra Wilson, Justin Chambers, Sandra Oh and Kate Walsh of “Grey’s Anatomy”, winner Favorite TV Drama

  • EUPHORIA


    Image Credit: HBO

    Eric Dane, Jacob Elordi

  • HBO Max FYC Event For “Euphoria”


    Image Credit: Rodin Eckenroth/FilmMagic

    Alexa Demie, Hunter Schafer, Eric Dane, Maude Apatow, Zendaya, Barbie Ferreira, Sydney Sweeney, Sam Levinson, and Colman Domingo attend the HBO Max FYC event for “Euphoria” at Academy Museum of Motion Pictures on April 20, 2022

  • Euphoria Premiere After Party at ATX Television Festival, 2019


    Image Credit: Gary Miller/Getty Images for FIJI Water

    Eric Dane, Zendaya in Austin, Texas

  • “Euphoria” Season 2 Photo Call


    Image Credit: Jeff Kravitz/FilmMagic for HBO

    Colman Domingo, Eric Dane, Zendaya, Sam Levinson, Hunter Schafer, Sydney Sweeney, Jacob Elordi, Dominic Fike, Maude Apatow, Austin Abrams, and Angus Cloud

  • HBO Max “Euphoria” FYC


    Image Credit: Jon Kopaloff/FilmMagic for HBO

    Eric Dane, Colman Domingo and Chloe Cherry 

  • THE LAST SHIP, 2018


    Image Credit: TNT / courtesy Everett Collection

    Eric Dane, ‘Fog of War’, (Season 5, ep. 502, aired Sept. 16,)

  • “The Last Ship” At Comic-Con International, 2015


    Image Credit: Joe Scarnici/Getty Images for TNT

    Jocko Sims, writer/producer Hank Steinberg, Eric Dane, Rhona Mitra, Travis Van Winkle, Marissa Neitling and Adam Baldwin

  • ‘The Last Ship’ Washington D.C. Screening


    Image Credit: Paul Morigi/Getty Images for Turner

    The Secretary of the Navy Ray Mabus and Admiral Dawn Cutler present actor Eric Dane with a Shadow Box containing Navy medals earned by his father

  • MARLEY & ME, 2008


    Image Credit: Fox 2000 Pictures/Courtesy Everett Collection

    Owen Wilson, Eric Dane

  • “Marley & Me” Los Angeles Premiere


    Image Credit: Lester Cohen/WireImage

    Director David Frankel, Jennifer Aniston, Owen Wilson, Clyde the dog and actor Eric Dane

  • BURLESQUE, 2010


    Image Credit: Screen Gems/courtesy Everett Collection

    Christina Aguilera, Eric Dane

  • ‘Private Practice’


    Image Credit: Eric McCandless/Disney General Entertainment Content via Getty Images

    Eric Dane, Kate Walsh – “Another Second Chance”

  • PRIVATE PRACTICE, 2009


    Image Credit: ric McCandless / ABC / Courtesy Everett Collection

    Eric Dane, Kate Walsh, ‘Ex-Life’, (Season 2, episode 16, aired February 12)

  • VALENTINE’S DAY, 2010


    Image Credit: Ron Batzdorff/©New Line Cinema/courtesy Everett Collection

     Jessica Biel, Eric Dane

  • “Valentine’s Day” Los Angeles Premiere


    Image Credit: Lester Cohen/WireImage

    Carter Jenkins, Eric Dane, Jamie Foxx, Jessica Biel, Jennifer Garner, Bradley Cooper, Hector Elizondo, Anne Hathaway, Director Garry Marshall, actors George Lopez, Taylor Lautner and Topher Grace at Grauman’s Chinese Theatre

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    BAD BOYS: RIDE OR DIE, Eric Dane, 2024. © Sony Pictures Releasing / Courtesy Everett Collection

  • Los Angeles Premiere Of Columbia Pictures’ “Bad Boys: Ride Or Die” – Arrivals

    HOLLYWOOD, CALIFORNIA – MAY 30: (L-R) Billie Beatrice Dane, Eric Dane and Georgia Geraldine Dane attend the Los Angeles Premiere of Columbia Pictures’ “Bad Boys: Ride or Die” at TCL Chinese Theatre on May 30, 2024 in Hollywood, California. (Photo by Axelle/Bauer-Griffin/FilmMagic)

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    GIDEON’S CROSSING, Eric Dane, 2000-2001, ©Touchstone Television/courtesy Everett Collection

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    ONE FAST MOVE, from left: Edward James Olmos, Eric Dane, 2024. © Amazon Prime Video / Courtesy Everett Collection

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    DANGEROUS WATERS, from left: Odeya Rush, Eric Dane, 2023. © Signature Films /Courtesy Everett Collection

  • The 2019 ESPYs – Inside

    LOS ANGELES, CALIFORNIA – JULY 10: (L-R) Patrick Mahomes, Eric Dane, Lilly Singh, and Jared Goff attend The 2019 ESPYs at Microsoft Theater on July 10, 2019 in Los Angeles, California. (Photo by Rich Fury/Getty Images)

  • Sixth Annual Chrysalis Butterfly Ball – Red Carpet

    Eric Dane, James Van Der Beek, Heather McComb, Soleil Moon Frye and Rebecca Gayheart (Photo by Jeff Vespa/WireImage)

  • Los Angeles Special Screening Of “One Fast Move”

    CULVER CITY, CALIFORNIA – AUGUST 06: (L-R) Producer Mike Karz, actors Austin North, Edward James Olmos, Adam Thomas Ziemba and Eric Dane, director Kelly Blatz and producer Bill Bindley attend a screening of “One Fast Move” at Culver Theater on August 06, 2024 in Culver City, California. (Photo by Michael Tullberg/Getty Images)

  • “Countdown” Premiere and After-Party

    LOS ANGELES, CALIFORNIA – JUNE 18: (L-R) Jensen Ackles and Eric Dane attend the “Countdown” Premiere and After-Party on June 18, 2025 in Los Angeles, California. (Photo by Frazer Harrison/Getty Images for Prime Video)

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    AMERICANA, Eric Dane, 2023. ph: Ursula Coyote /© Lionsgate /Courtesy Everett Collection

  • “Countdown” Premiere and After-Party

    LOS ANGELES, CALIFORNIA – JUNE 18: (L-R) Uli Latukefu, Elliot Knight, Jensen Ackles, Eric Dane, Violett Beane and Jessica Camacho attend the “Countdown” Premiere and After-Party on June 18, 2025 in Los Angeles, California. (Photo by Frazer Harrison/Getty Images for Prime Video)

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    REDEEMING LOVE, from left: Abigail Cowen, Eric Dane, 2022. © Universal Pictures / Courtesy Everett Collection

  • Turner Upfront 2015 – Green Room

    NEW YORK, NY – MAY 13: Eric Dane and Rhona Mitra attend the Turner Upfront 2015 at Madison Square Garden on May 13, 2015 in New York City.
    25201_002_TW_0228.JPG (Photo by Theo Wargo/Getty Images for Turner)

  • Brilliant Minds – Season 2

    BRILLIANT MINDS — “Fire Fighter” Episode 209 — Pictured: (l-r) Zachary Quinto, Eric Dane — (Photo by: Pief Weyman/NBC via Getty Images)

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    LITTLE DIXIE, from left: Frank Grillo, Eric Dane, 2023. © Paramount Pictures / Courtesy Everett Collection

  • 21st Annual Screen Actors Guild Awards

    LOS ANGELES, CA – January 26, 2015 Actor Eric Dane and Emmy Rossum on stage at the 21st Annual Screen Actors Guild Awards at the Shrine Auditorium in Los Angeles, CA on Sunday, January 25, 2015 (Robert Gauthier / Los Angeles Times via Getty Images)

  • 43rd AFI Life Achievement Award Honoring Steve Martin – Backstage And Audience

    HOLLYWOOD, CA – JUNE 04: Actors Rebecca Gayheart (L) and Eric Dane attend the 43rd AFI Life Achievement Award Gala honoring Steve Martin at Dolby Theatre on June 4, 2015 in Hollywood, California. (Photo by Frazer Harrison/Getty Images for AFI)

  • Auto Club 400 NASCAR Sprint Cup Series Event Weekend

    FONTANA, CA – MARCH 20: Actor and Grand Marshall of the Auto Club 400 NASCAR Sprint Cup Series Event Weekend Eric Dane arrives at the Auto Club Speedway on March 20, 2016 in Fontana, California. (Photo by Frederick M. Brown/Getty Images)

  • Comic-Con International 2016 – Entertainment Weekly: Brave New Warriors

    SAN DIEGO, CA – JULY 22: (L-R) Actors Josh Holloway, Dominic Cooper and Eric Dane attend the Entertainment Weekly: Brave New Warriors event during Comic-Con International 2016 at San Diego Convention Center on July 22, 2016 in San Diego, California. (Photo by Alberto E. Rodriguez/Getty Images)

  • 16th Annual Chrysalis Butterfly Ball – Arrivals

    LOS ANGELES, CA – JUNE 03: Chrysalis Butterfly Ball Co-chair Rebecca Gayheart-Dane (L) and Actor Eric Dane with Georgia Dane and Billie Beatrice Dane at the 16th Annual Chrysalis Butterfly Ball on June 3, 2017 in Los Angeles, California. (Photo by Matt Winkelmeyer/Getty Images for Chrysalis Butterfly Ball)

  • Sixth Annual Chrysalis Butterfly Ball – Arrivals

    Patrick Dempsey and Eric Dane during Sixth Annual Chrysalis Butterfly Ball – Arrivals at Home of Susan Harris & Hayward Kaiser in Mandeville Canyon, California, United States. (Photo by Jon Kopaloff/FilmMagic)

  • Monte Carlo Television Festival 2007 – Day 3

    MONTE CARLO, MONACO – JUNE 13: In this handout released by the 2007 TV Festival Organization, actress Rebecca Gayheart, Prince Albert II of Monaco and actor Eric Dane pose in the courtyard of the Monaco Palace as they attend a reception on the third day of the 2007 Monte Carlo Television Festival on June 13, 2007 in Monaco. (Photo by Handout/2007 TV Festival Organization via Getty Images)

  • The White House Correspondents’ Association Dinner

    WASHINGTON – APRIL 26: Actor Eric Dane arrives at the White House Correspondents’ Association dinner on April 26, 2008 in Washington, DC. (Photo by Nancy Ostertag/Getty Images)

  • 7th Annual Chrysalis Butterfly Ball – Inside

    (L-R) Actors Ashton Kutcher, Eric Dane, Demi Moore, and Soleil Moon Frye attend the 7th Annual Chrysalis Butterfly Ball at a private residence on May 31, 2008 in Los Angeles, California. (Photo by Alexandra Wyman/WireImage)