Mouse study shows how liraglutide briefly rewires gut bacterial communities
A mouse study tracks how a leading GLP-1 drug alters gut bacteria over time, offering new clues to…
Microbial metabolites could help improve functional cure rates for hepatitis B
Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure…
Bile acid buildup linked to aggressive breast cancer progression
A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of…
Targeted therapy doubles progression-free survival in rare bile duct cancer
Results of the ongoing eNRGy trial, a single-arm, multicenter, global phase 2 clinical trial evaluating zenocutuzumab in solid…
Gene therapy shows promise against deadly childhood liver disease
A new gene therapy has been used to successfully treat a deadly childhood liver disease using mice that…
Synthetic gut communities reveal how diet rewires the microbiome
By simplifying the gut’s microbial complexity, synthetic communities could help scientists pinpoint how specific foods influence microbial function,…
Gene therapy successfully treats deadly childhood liver disease in mice
A new gene therapy has been used to successfully treat a deadly childhood liver disease using mice that…
New gel coating delivers anti-inflammatory antibodies directly to the esophagus
There are few treatment options available for people with disorders of the esophagus. Delivering drugs directly to this…
Microbially modified bile acids influence sleep apnea outcomes
Studies in mice reveal a new target for potentially treating and preventing life-threatening cardiovascular complications in the millions…
Link Between Gut Microbes and Sleep Apnea Discovered
Summary: A new study has identified a novel therapeutic target to prevent life-threatening heart and metabolic complications in…
Biliary epithelial cells found to actively prevent liver fibrosis development
Many liver diseases share a common characteristic: fibrosis, that is, the progressive accumulation of scarring in the liver…
New roadmap links liver cancer biology to immunotherapy and precision medicine
A new review from the Icahn School of Medicine at Mount Sinai and the Hospital Clínic de Barcelona…