Bioinformatics - Ireland

iNOME-seq: in vivo simultaneous genome-wide mapping of chromatin accessibility, nucleosome positioning, DNA-binding protein sites, and DNA methylation in Arabidopsis | Genome Biology

October 22, 2025

Plant lines and growth conditions The plant lines used in this study were derived from A. thaliana wild-type…

MultiModalGraphics: an R package for graphical integration of multi-omics datasets | BMC Bioinformatics

October 21, 2025

MultiModalGraphics is an R/Bioconductor package that leverages object-oriented S4 classes to visualize multimodal biological data with embedded statistical…

GGenetics

World Record Set For Fastest Genome Sequencing | Health

October 20, 2025

Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…

GGenetics

October 17, 2025

Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…

GGenetics

SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology

October 16, 2025

Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…

SScience

Reference genome bias in light of species-specific chromosomal reorganization and translocations | Genome Biology

October 15, 2025

Hohenlohe PA, Funk WC, Rajora OP. Population genomics for wildlife conservation and management. Mol Ecol. 2021;30:62–82. PubMed Google…

GGenetics

SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data | BMC Bioinformatics

October 14, 2025

Software architecture SAGPEK mainly processes Sanger sequencing results of two kinds of samples: diploids such as humans and…

GGenetics

A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology

October 10, 2025

K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…

GGenetics

Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology

October 3, 2025

Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…

TTechnology

TrueSpot: a robust automated tool for quantifying signal puncta in fluorescent imaging | Genome Biology

September 29, 2025

TrueSpot uses an automated threshold selection algorithm that utilizes multiple approaches TrueSpot accepts either a 2D image or…

GGenetics

Advances in haplotype phasing and genotype imputation

September 24, 2025

Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. A map of recent positive selection in…

GGenetics

September 23, 2025

Mastermind® FLEX Data powers Compass Bioinformatics’s InheriNext® platform, bringing unparalleled genomic evidence to leading institutes across US, Japan,…