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Browsing Tag

Cancer Research

55 posts
GGenetics
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function
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Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

  • October 22, 2025
Institute of Medical Genetics, University of Zurich, Zurich, Switzerland Reza Asadollahi, Paranchai Boonsawat, Dennis Kraemer & Anita Rauch Faculty of Engineering and…
GGenetics
Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs
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Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs

  • October 21, 2025
Cohorts We used published data (GEO accession no. GSE162632) to study the effect of 12 h of ex vivo…
HHealthcare
Yahoo news home
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Advocate and cancer survivor Lainie Jones dies at 41 in Fort Lauderdale

  • October 20, 2025
Lainie Jones believed in the power of being early. She credited early detection as the reason she survived…
GGenetics
Genotyping sequence-resolved copy number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes
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Genotyping sequence-resolved copy number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes

  • October 20, 2025
Constructing the pangenome-derived allele databaseSearch and extraction of initial genes of interest from pangenome assemblies Our pangenome cohort…
GGenetics
Association of genetic variants in m1A modification core genes and neuroblastoma risk | BMC Cancer
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Association of genetic variants in m1A modification core genes and neuroblastoma risk | BMC Cancer

  • October 18, 2025
Park JR, Kreissman SG, London WB, Naranjo A, Cohn SL, Hogarty MD, et al. Effect of tandem autologous…
GGenetics
Redefining cellular reprogramming with advanced genomic technologies
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Redefining cellular reprogramming with advanced genomic technologies

  • October 18, 2025
Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…
HHealth
Curcumin in prostate cancer: a systematic review of molecular mechanisms and nanoformulated therapeutic strategies | BMC Cancer
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Curcumin in prostate cancer: a systematic review of molecular mechanisms and nanoformulated therapeutic strategies | BMC Cancer

  • October 18, 2025
Curcumin, a dietary polyphenol derived from Curcuma longa, has been extensively studied for its pleiotropic biological activities, particularly…
GGenetics
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
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Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers

  • October 18, 2025
Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration patterns1. It contributes…
GGenetics
Characterization of induced cohesin loop extrusion trajectories in living cells
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Characterization of induced cohesin loop extrusion trajectories in living cells

  • October 17, 2025
Experiments performed in this study did not require ethics board approval. Cell culture HAP1 cells were cultured in…
HHealth
Global, regional, and national burden of lip and oral cavity cancer and projections to 2036 | BMC Cancer
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Global, regional, and national burden of lip and oral cavity cancer and projections to 2036 | BMC Cancer

  • October 14, 2025
Our comprehensive analysis of the GBD 2021 data elucidates significant temporal and spatial patterns in the global burden…
GGenetics
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
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Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health

  • October 11, 2025
To identify genes associated with either adult BMI or T2D risk, we performed association testing using WGS data…
GGenetics
Forensic genetics in the omics era
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Forensic genetics in the omics era

  • October 10, 2025
Jeffreys, A. J., Wilson, V. & Thein, S. L. Individual-specific ‘fingerprints’ of human DNA. Nature 316, 76–79 (1985).…
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