New pair of techniques can speed up the search for better tuberculosis drugs
Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb) is the world’s deadliest single-agent caused infection, responsible for 1.23…
Study uncovers self-propelled actin filaments that shape living cells
Every time a white blood cell engulfs a bacterium, a neuron extends a projection to connect with a…
High-dose DHA reaches the brain but fails to protect memory
High-dose DHA successfully reached the brains of older adults at increased risk of Alzheimer’s disease, but the two-year…
Targeting lipid enzymes triggers starvation states in aggressive tumor cells
While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for…
Light-driven nanomotors improve multimodal breast cancer treatment efficacy
The nanomotor starts with bowl‑shaped mesoporous polydopamine (PDA) nanoparticles. These biocompatible bowls are loaded with two key payloads:…
AI-based generative framework create all-atom models of proteins in motion
Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins. When molecules of a drug…
Researchers discover how cell membrane composition drives cancer proliferation
Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell…
The molecular mechanism that turns cool temps into nerve signals
When you reach into a bucket of ice, open your front door on a snowy day, or feel…
Study uncovers how tuberculosis bacteria fuel themselves during infection
Researchers at The Hospital for Sick Children (SickKids) have uncovered how the bacteria that causes tuberculosis fuels itself during infection, providing new insights…
Customizable protein platforms offer new hope for cancer treatment
Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the…
Two bacterial shutdown modes explain antibiotic persistence and relapse
New study reveals that bacteria can survive antibiotic treatment through two fundamentally different “shutdown modes,” not just the…
Study shines light on how P2X4 receptor can be inhibited
A study carried out by the University of Bonn and the University Hospital Bonn throws light on how…