Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
A striking immune cell pattern emerges around a person’s 100th birthday
Rare immune cells found at strikingly high levels in people who live beyond 110 reveal an unusual pattern…
New AI model reveals hidden code behind gene activation
Precise activation of tens of thousands of genes is critical for healthy development and growth. Specialized segments of…
Deliverome project maps cell surface proteins for better drug delivery
For a new drug to work in the human body, it must make its way to the exact…
Neurogenesis stalls in the brains of adults with major depressive disorder, study shows
Most of our brain’s 100 billion neurons are created before we’re born, but the trickle of neurons created in the adult brain hippocampus could be instrumental in preventing depression, suggest findings from a new…
Bonsai software visualizes complex biological data as branching trees
Modern biology research can now generate valuable data on an unprecedented scale. But there is one major obstacle:…
Younger lung cancer patients show more targetable gene alterations
Younger adults with non-small cell lung cancer are significantly more likely than older patients to have genetic alterations…
Cryo-EM provides real-time glimpse of cellular machinery reading DNA inside living organisms
All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the…
Scientists create brain organoids with distinct cortical regional identity
The human brain is often described as one of the most complex structures in biology, and much of…
Wake-activated brain circuits reveal what drives the urge to sleep
By mapping the brain during prolonged wakefulness, researchers pinpointed neuronal populations whose activity rises with time awake and…
Researchers map DNA’s physical code using large-scale simulations
Nearly every cell in the human body contains essentially the same genetic information, yet different cells activate different…
Intravenous iron before heart surgery cuts transfusion needs
Giving intravenous iron to patients with anemia before heart surgery reduces the need for a red blood transfusion…