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Browsing Tag

Cytokine

11 posts
HHealth
Study: CD4 CTLs in supercentenarians: Signs of adaptive expansion in healthy aging. Image Credit: Sean Pavone   / Shutterstock
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A striking immune cell pattern emerges around a person’s 100th birthday

  • August 24, 2026
Rare immune cells found at strikingly high levels in people who live beyond 110 reveal an unusual pattern…
HHealth
Study: Effects of perilla oil on platelet and inflammatory responses in healthy smokers: a randomized, double-blind, placebo-controlled, parallel trial. Image Credit: Nungning20 / Shutterstock
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Perilla oil may curb platelet reactivity and inflammatory signaling in smokers

  • August 4, 2026
An eight-week Korean trial links ALA-rich perilla oil to changes in platelet behavior and immune signaling, while highlighting…
HHealth
Study reveals mechanism underlying HBV-induced liver inflammation
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Study reveals mechanism underlying HBV-induced liver inflammation

  • July 17, 2026
Chronic hepatitis B virus (HBV) infection remains a major cause of global liver morbidity, leading to progressive necroinflammation…
HHealth
Study: Melatonin modulates inflammation in human fetal membranes: an ex vivo approach. Image Credit: Pikovit / Shutterstock
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Melatonin dampens fetal membrane inflammation linked to preterm birth

  • June 29, 2026
A new ex vivo study reveals how melatonin may calm infection-triggered fetal membrane inflammation, offering fresh clues for…
TTechnology
Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment
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Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment

  • June 29, 2026
A new study suggests that clearing symptom-driving nasal viruses could calm allergic inflammation and open a fresh treatment…
SScience
Streamlining immunological research using VIAFLO 96 and VIAFLO 384 handheld electronic pipettes
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New biomarkers identify trauma patients at risk for chronic critical illness

  • June 25, 2026
New research, published in The Journal of Immunology, identified biomarkers of a distinct immune profile that could be…
HHealth
Bowls with tasty almonds on color background
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Can eating almonds reduce inflammation in obesity?

  • March 12, 2026
A six-week randomized trial shows that adding almonds to the daily diet of adults with obesity can improve…
HHealth
Review: Zinc: A metallic shield against cardiac inflammation. Image Credit: Cagkan Sayin / Shutterstock
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How zinc deficiency could worsen heart inflammation and what that means for patients

  • March 2, 2026
New research suggests that zinc does far more than support immunity, revealing intricate molecular switches that may influence…
HHealth
Opinion: Lung cancer in never smokers: from early detection to prevention. Image Credit: Jo Panuwat D / Shutterstock
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Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

  • February 15, 2026
A novel nasal booster approach may help close the gap between systemic vaccination and infection-blocking mucosal immunity, offering…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
HHealth
Amino acid metabolism shapes the tumor immune microenvironment and therapy response
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Engineered CAR T cells show promise against solid tumors

  • October 3, 2025
Chimeric antigen receptor (CAR) T cell therapy, which uses a patient’s own immune cells to fight cancer, has…
Ireland
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