Real-time molecular recorders expose the inner lives of cells
Illustration: The Project Twins Cells are poor storytellers. They live complex, eventful lives — dividing, migrating, responding to…
CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold
Input embeddings In CellNavi, we use single-cell raw count matrices as the only input. Specifically, the single-cell sequencing…
Spatial architecture of development and disease
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …
NAD+-dependent Sirt6 is a key regulator involved in telomere shortening of in vitro-cultured preimplantation embryos
Telomere shortening, DNA damage and elevated oxidative stress in blastocysts cultured in vitro Figure 1a depicts the morphology of…