Weizmann study reveals how DNA repair enzymes choose targets
When a wound does not heal properly, it leaves a scar. Similarly, mutations – which are permanent changes…
Researchers find unexpected protein regulator of leukemia drug sensitivity
How cells respond to the leukemia drug 6-thioguanine still holds surprises: A new study, led by researchers from…
New study identifies key pathway for delivering antisense cancer drugs
Antisense oligonucleotides (ASOs) have been proposed as a therapeutic approach to shut down the production of faulty proteins…
Folic acid relies on vitamin A pathway to prevent birth defects
For decades, we’ve known that folic acid can help prevent serious birth defects of the brain and spinal…
Two-gene interaction reveals metastatic risk in breast cancer
Why do some breast cancer patients face a much higher risk of distant metastasis, while others with seemingly…
Researchers discover smart molecular glue that activates inside oxidative cancer cells
Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein…
Scientists Add Unlikely New Member to World’s Carnivorous Plants
More than 150 years after Charles Darwin first wondered whether certain sticky-leaved Saxifraga plants might be secretly carnivorous,…
Study reveals evolutionary shift in gene crucial for the human nervous system
Certain variants in the PSPH gene, which encodes an enzyme called phosphoserine phosphatase, prevent the body from making…
Photoreceptors possess internal recycling system to preserve vision
For decades, scientists believed that photoreceptors in the retina relied primarily on neighboring support cells, known as the…
Researchers identify key barrier preventing self repair of heart cells
Specialized cells in our body make biological tradeoffs to do certain jobs. To support large and hardworking hearts…
AI redesign helps enzymes evolve beyond natural limits
By stabilizing enzyme starting points before evolution, researchers opened new mutational routes for engineering highly specific proteases, including…
Automated workflow speeds bacterial sample preparation for genetic sequencing
Biomedical engineers at Brown University have developed a fully automated workflow that simplifies and accelerates the preparation of…