Facial wound secrets revealed for scarless repair
Tweaking a pattern of wound healing established millions of years ago may enable scar-free injury repair after surgery…
New insights into long-term liver injury after Kasai portoenterostomy for biliary atresia
BA is characterized by early destruction of the bile ducts, leading to cholestasis, inflammation, and rapid fibrosis shortly…
Preclinical study reveals potential new treatment for severe liver fibrosis
Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis – a dangerous, disease-induced build-up of…
Single-cell RNA-seq reveals FBLN7’s role in adipose tissue fibrosis
Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance.…
Scientists outline how organ rejuvenation strategies could solve the donor shortage
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
Enterprise Therapeutics publishes results of Phase 1 study of ETD001, a novel inhaled ENaC blocker for treatment of Cystic Fibrosis, in The Journal of Cystic Fibrosis
Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve…
Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments
A new multi-site study led by researchers at CU Anschutz shows that people with cystic fibrosis (CF) who…
Blocking immune cell signals reduces scar tissue formation in wounds
Researchers at the University of Arizona uncovered a previously unknown population of circulating immune cells that play a…
Study advances the possibility of age-based pancreatic cancer treatment
While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging…
New insights reveal how TCF and LEF proteins control Wnt signaling and disease progression
Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins…
New biofilm discovery may pave way to undermining antibiotic-resistant Pseudomonas
The bacterium known as Pseudomonas aeruginosa is an unwelcome visitor in the human body. Serious infections can result…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…