Cells filter physical forces based on duration to detect disease
Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling…
Biliary epithelial cells found to actively prevent liver fibrosis development
Many liver diseases share a common characteristic: fibrosis, that is, the progressive accumulation of scarring in the liver…
Cystic fibrosis therapies significantly reduce the need for pediatric lung transplants
Pediatric lung transplant specialist Christian Benden, MD, described the future for children who need lung transplants: fewer operations…
Gut-liver changes drive foodborne infection severity in fatty liver disease
A research team led by the University of California, Irvine’s Joe C. Wen School of Population & Public…
Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…
New algorithm enables precise subtyping of metabolic liver disease
Metabolic-associated steatotic liver disease (MASLD) is a clinically heterogeneous condition with highly variable outcomes affecting more than 30%…
EVA1A regulates fatty acid transporter CD36 in fatty liver disease
Metabolic Dysfunction-Associated Steatotic Liver Disease（MASLD） is characterized by excessive accumulation of lipids in hepatocytes and is closely associated…
New fragmentome technology can detect early liver fibrosis and cirrhosis
Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence (AI)-based liquid biopsy test using genome-wide cell-free…
Engineers develop highly precise gene editor for safer cystic fibrosis treatments
Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic “base…
Artificial lung keeps patient alive after lung removal
By replacing both breathing and circulatory buffering, a novel artificial lung bought critical time after lung removal, revealed…
Facial wound secrets revealed for scarless repair
Tweaking a pattern of wound healing established millions of years ago may enable scar-free injury repair after surgery…
New insights into long-term liver injury after Kasai portoenterostomy for biliary atresia
BA is characterized by early destruction of the bile ducts, leading to cholestasis, inflammation, and rapid fibrosis shortly…