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Browsing Tag

Gene Function

33 posts
GGenetics
KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease
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KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease

  • August 23, 2025
Precision Healthcare University Research Institute, Queen Mary University of London, London, UK Segun Fatumo, Oyesola Ojewunmi, Rebecca Camenzuli, Christopher Kintu & Claudia Langenberg…
GGenetics
Imaging-based multimodal profiling of single cells with STAMP
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Imaging-based multimodal profiling of single cells with STAMP

  • August 22, 2025
Single-cell RNA sequencing (scRNA-seq) has dramatically advanced our ability to dissect complex biological systems at cellular resolution. However,…
GGenetics
A comparison of 27 Arabidopsis thaliana genomes and the path toward an unbiased characterization of genetic polymorphism
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A comparison of 27 Arabidopsis thaliana genomes and the path toward an unbiased characterization of genetic polymorphism

  • August 20, 2025
DNA extraction and sequencing For long-read sequencing, we began with 3-week-old plants grown in soil that had been…
GGenetics
Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy
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Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy

  • August 17, 2025
Cancer is a genetic disease stemming from a combination of inherited and acquired mutations. Much of our understanding…
GGenetics
Methods and applications of in vivo CRISPR screening
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Methods and applications of in vivo CRISPR screening

  • August 17, 2025
Auton, A. et al. A global reference for human genetic variation. Nature 526, 68–74 (2015). PubMed  Google Scholar …
GGenetics
Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs
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Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs

  • August 17, 2025
Ethics We received approval to access and analyze deidentified genetic and phenotypic data from the two cohorts from…
GGenetics
Large-scale genome-wide analyses of stuttering
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Large-scale genome-wide analyses of stuttering

  • August 17, 2025
Yairi, E. & Ambrose, N. Epidemiology of stuttering: 21st century advances. J. Fluen. Disord. 38, 66–87 (2013). Google…
GGenetics
Analysis of individual patient pathway coordination in a cross-species single-cell kidney atlas
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Analysis of individual patient pathway coordination in a cross-species single-cell kidney atlas

  • August 16, 2025
GBD Chronic Kidney Disease Collaboration Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis…
GGenetics
Tracing the evolution of sequencing into the era of genomic medicine
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Tracing the evolution of sequencing into the era of genomic medicine

  • August 16, 2025
Sanger, F., Nicklen, S. & Coulson, A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA…
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