Breast cancer cells use a molecular switch to survive stress
Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust…
Scientists map the genetic control system behind FOXP3 in immune cells
The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer,…
TAU researchers develop groundbreaking gene therapy to treat hearing, balance disabilities
“These findings highlight the potential of self-complementary AAVs to reduce dose requirements, minimize toxicity, and broaden clinical use…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Two main methods for discovering disease genes reveal distinct aspects of biology
The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While…
Bowel cancer’s “Big Bang” moment reveals how the disease takes shape
Like the astronomical explosion that kickstarted the universe, bowel cancer has a “Big Bang” moment which determines how…
Study finds high intake of ultra-processed foods tied to reduced DNA methylation
Researchers have found that women who consume more ultra-processed foods exhibit widespread differences in DNA methylation, suggesting early…
Redefining control in anaerobic microbiome workflows
In this interview, Sheela Muley, Product Manager at Molecular Devices, and Dr Sushmita Sudarshan, Application Scientist in Assay Development at Molecular Devices,…
PTGES3 emerges as key regulator of androgen receptor in prostate cancer
A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player…
Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Massive cross-ancestry study explains why obesity risks differ around the world
By analyzing genetic data from more than 800,000 individuals across six ancestries, researchers have identified previously unknown obesity…
Two microbial metabolites compete to control the cells’ protein building machinery
The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in…