New analysis reveals fundamental flaws in widely used measures of biological aging
A landmark review published today in Genomic Psychiatry challenges researchers to fundamentally reconsider how the field measures and…
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
Researchers discover new mutation hotspot in the human genome
Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
New AMR portal provides large-scale curated data to to advance antimicrobial resistance research
Antimicrobial resistance (AMR) is a growing health challenge, reducing the effectiveness of life-saving treatments and increasing the risk…
Landmark Japanese genome cohort reveals best practices for managing massive DNA databases
At a time when large-scale human genome analysis was not yet common, the Tohoku Medical Megabank Organization (ToMMo)…
Scientists map the genetic control system behind FOXP3 in immune cells
The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer,…
Single-cell study reveals how HPV shapes immune landscape in penile cancer
Although penile cancer represents less than 1% of male malignancies, it carries substantial physical and psychological burden, with…
The caffeine conundrum in rapid depression treatments
Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic…
Global survey reveals struggles of young mothers living with advanced breast cancer
Nearly half of all women aged younger than 40 who live with advanced breast cancer have children under…