Younger lung cancer patients show more targetable gene alterations
Younger adults with non-small cell lung cancer are significantly more likely than older patients to have genetic alterations…
Weizmann study reveals how DNA repair enzymes choose targets
When a wound does not heal properly, it leaves a scar. Similarly, mutations – which are permanent changes…
AI model predicts cancer subtype, genetic mutations, and survival outcomes across 32 solid tumors
Researchers have developed a novel AI model that can analyze a routine whole histopathology image and simultaneously predict…
Pediatric rheumatic diseases have unique genetic architecture compared to adults
Researchers from Children’s Hospital of Philadelphia (CHOP) have found that pediatric-onset rheumatic and inflammatory diseases have distinct genetic…
Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis
Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence…
Comprehensive brain cell map opens new avenues for Alzheimer’s therapies
The brain’s immune cells are increasingly recognized as key players in Alzheimer’s disease, but exactly how they change…
New human genome benchmark captures both parental copies with near-perfect accuracy
By capturing both inherited chromosome sets and reaching genomic regions missed by conventional benchmarks, T2T-HG002 could help shift…
International team builds comprehensive cancer models for future drug development
To develop new targeted treatments for cancer, scientists need tissue models that accurately represent the genetic and molecular…
Cells share universal on switches but evolve unique strategy to silence genes
The signals that cells use to switch genes on have remained almost unchanged across two billion years of…
New computational technique traces ghost ancestry in modern human genomes
UC Berkeley researchers have identified regions of DNA that humans inherited from two unknown ancestors as a result…
Occult hepatitis B mutations drive liver cancer growth via Akt mTOR pathway
Occult hepatitis B virus (OBI) infection presents a significant global health challenge, notoriously flying under the radar of…
New ctDNA blood test improves personalized prostate cancer treatment
A noninvasive DNA blood test can identify metastatic castration-resistant prostate cancer (mCRPC) patients who are most likely to…