Engineered CAR T cells show promise against solid tumors
Chimeric antigen receptor (CAR) T cell therapy, which uses a patient’s own immune cells to fight cancer, has…
Post-operative radiation therapy reduces pelvic relapse in high-risk bladder cancer
Radiation therapy could be an underused tool to reduce pelvic relapse risk for patients with locally advanced, muscle-invasive…
New findings show lymph nodes educate T cells to combat disease
A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the…
Scientists Find a Way to “Bulletproof” T Cells Against Cancer
Researchers at the University of Pittsburgh have discovered that the harsh environment inside tumors, characterized by low oxygen…
Adjuvant chemo-immunotherapy may benefit patients with resected stage IB–IIIA NSCLC, trial suggests
Interim results from the NADIM ADJUVANT Phase III trial, led by the Spanish Lung Cancer Group (GECP), suggest…
New method uncovers how extracellular vesicles impact immune response in cancer
Certain types of biochemical processes can impair the immune system’s ability to recognize and kill cancer cells. Purdue…
New study uncovers a surprising mechanism of resistance to immunotherapy
A new international study led by researchers at Moffitt Cancer Center, the Karolinska Institutet and the University of…
Early intervention anti-Aβ immunotherapy attenuates microglial activation without inducing exhaustion at residual plaques | Molecular Neurodegeneration
Mice All animal experiments were approved by the Ethical Review Board of the Government of Upper Bavaria. Mice…
Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors
A new study, led by researchers at Children’s Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA…
Amino acid metabolism shapes the tumor immune microenvironment and therapy response
The tumor microenvironment is not just a site of cancer growth—it is a high-stakes metabolic contest where tumor…
A single genetic mutation may have made humans more vulnerable to cancer than chimpanzees
(SACRAMENTO) New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why…