E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression
An international collaborative study has identified the E2F2 protein as a potential new therapeutic target to prevent metabolic…
Fatty acids found to be a primary driver of triple-negative tumor growth
A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast…
Reduced endocannabinoid-related lipids found in patients with NSAID-exacerbated respiratory disease
NSAID-exacerbated respiratory disease, N-ERD, is associated with measurable changes in concentrations of lipid mediators involved in inflammation and…
Understanding how lipids activate LC3-associated phagocytosis
LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a…
Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk
Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest…
Rare ABCA7 gene variants linked to Alzheimer’s risk
A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to…
Targeting metabolic reprogramming to overcome immune suppression in head and neck cancer
Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide…
Researchers discover a direct pathway for macrophage cleanup
Macrophages are part of the immune system’s frontline; they attack and eat invaders to protect surrounding cells. They,…
Visualizing lipid transport inside living cells with fluorescence microscopy
To the point: New technique to image single lipids: Lipids are notoriously difficult to detect with light microscopy.…
UNSW researchers identify key protein that regulates fat storage in cells
UNSW research has shed light on how cells in the body manage and store fat, potentially offering new…
Metabolic health plays larger role than weight gain in pregnancy outcomes
Metabolic health before and during pregnancy may have a bigger influence on risks for mother and baby than…
Certain dietary fats found to trigger hard-to-treat asthma in children
Researchers at Children’s Hospital of Philadelphia (CHOP) found that certain lipids, or fats, in obesity-causing foods also cause…