Metformin targets the gut instead of the liver to lower glucose
For decades, physicians and scientists thought metformin, the leading Type 2 diabetes medication taken by millions worldwide, mainly…
UCLA researchers build programmable artificial organelles using RNA
Just as the human body relies on organs such as the heart or liver for essential functions, cells…
Hepatitis C infection associated with reduced portal insulin levels
Background and aims Insulin resistance is a common extrahepatic manifestation of hepatitis C virus (HCV) infection (HCVi), but…
Biliary epithelial cells found to actively prevent liver fibrosis development
Many liver diseases share a common characteristic: fibrosis, that is, the progressive accumulation of scarring in the liver…
Advanced heart, kidney and metabolic disease linked to higher cancer risk
People with advanced heart, kidney and metabolic disease may face a higher risk of developing cancer, according to…
Study identifies key risk factors driving MASLD across populations
Background and aims Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 32% of the US adult population. The…
Restoring gut microbiome may prevent liver cancer in mice
Restoring the gut microbiome to its youthful state may hold the key to slowing aging and preventing liver…
Eating oranges daily may shift lipid patterns in fatty liver disease
A 4-week clinical trial explores whether everyday oranges can subtly influence lipid metabolism in fatty liver disease, revealing…
Circulating exosomal microRNAs offer a non-invasive biomarker for MASLD
Metabolic dysfunction-associated steatotic liver disease (MASLD) has become a global public health challenge with rapidly rising prevalence, especially…
New roadmap links liver cancer biology to immunotherapy and precision medicine
A new review from the Icahn School of Medicine at Mount Sinai and the Hospital Clínic de Barcelona…
Gut-liver changes drive foodborne infection severity in fatty liver disease
A research team led by the University of California, Irvine’s Joe C. Wen School of Population & Public…
EV-RNAs show promise for IBD diagnosis and treatment
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive…