Scientists uncover tRNA changes driving Chagas parasite transformation
The Chagas disease parasite (Trypanosoma cruzi) undergoes a major transformation throughout its life cycle in order to infect…
Researchers map DNA’s physical code using large-scale simulations
Nearly every cell in the human body contains essentially the same genetic information, yet different cells activate different…
Polydatin reduces ulcerative colitis by regulating intestinal immune cells
Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which recurrent intestinal inflammation can be difficult to…
Sprint exercise sends a very different molecular signal through the body
Just minutes of all-out sprint work produced a striking surge in circulating proteins and metabolites, revealing how exercise…
Natural gut molecule ould strengthen chickens’ immune response against bacterial infections
A naturally occurring gut molecule that could strengthen chickens’ immune response against a wide range of bacterial infections,…
Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis
Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence…
Folic acid relies on vitamin A pathway to prevent birth defects
For decades, we’ve known that folic acid can help prevent serious birth defects of the brain and spinal…
New study uncovers metabolic vulnerability in high-risk myelodysplastic syndromes
Researchers at the University of Colorado Anschutz Cancer Center have identified a previously unknown metabolic weakness in the…
New protein blueprint opens door for targeted Parkinson’s disease therapies
Researchers at Weill Cornell Medicine have uncovered how a key Parkinson’s protein called LRRK2 shifts between inactive and…
Study identifies a novel direct drug target for head and neck squamous cell carcinoma
Chemotherapy remains a cornerstone of treatment for head and neck cancers, the seventh-most common cancer type worldwide. However,…
Malaria infection causes permanent damage to the spleen immune cells
Macrophages formed in the bone marrow can only assume the function of embryonal phagocytes, or “scavenger cells,” to…
Rice University chemists develop cheaper way to synthesize drugs
Pharmaceutical drugs often rely on chemical compounds found in the body. Take phosphate, a common compound cells use…