A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…
Blocking platelet-activating factor reduces liver damage in cirrhosis
Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural…
Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease
Synaptic plasticity — the brain’s ability to modify the connections between neurons to support learning — is one…
Autoimmune thyroiditis promotes breast cancer progression: exploratory role of thyroid hormone receptor beta signaling disruption | Breast Cancer Research
Turken O, NarIn Y, DemIrbas S, Onde ME, Sayan O, KandemIr EG, et al. Breast cancer in association…
Dysfunctional mitochondria shown to initiate the onset of Parkinson’s
For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson’s disease. But…
Innovative research reveals FGD3 as a key player in breast cancer cell death
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the…
New NIH grants fuel research in oral cancer treatment and pain relief
Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University…
Loud noise exposure worsens motor deficits in Parkinson’s disease model
In the development of Parkinson’s disease, it may not be a good idea to turn the amp to…
Discovery explains why women face higher risk of Alzheimer’s and multiple sclerosis
New research by UCLA Health has identified a sex-chromosome linked gene that drives inflammation in the female brain,…
Gut probiotic Christensenella tenuis reduces endotoxemia and improves metabolism in obese mice
This study is reported by the team of Professor Shuang-jiang Liu from Shandong University. The study reveals that…
Calcium-induced release identified as key driver of dangerous muscle disorders
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without…