Scientists identify STING switch driving inflammation in Alzheimer’s disease
The brain has its own immune system, which detects threats and mounts a defense. A growing body of…
Calcium signals in microglia drive anxiety and compulsive behaviors
Researchers had previously discovered a population of immune cells within the brain that can act as accelerators and…
Celiac disease weakens gut microbes that digest fiber
The problem in celiac disease may not be what patients eat, but what their microbes can process; microbial…
Vitamin B3 shows promise for treating rare genetic disorder
Scientists at Gladstone Institutes have flipped the traditional approach to finding potential treatments for deadly diseases. Instead of…
Researchers show red blood cells drive better glucose tolerance at high altitude
New research reveals how hypoxia-driven red blood cell adaptations may reshape glucose regulation, offering fresh insight into diabetes…
A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…
Blocking platelet-activating factor reduces liver damage in cirrhosis
Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural…
Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease
Synaptic plasticity — the brain’s ability to modify the connections between neurons to support learning — is one…
Autoimmune thyroiditis promotes breast cancer progression: exploratory role of thyroid hormone receptor beta signaling disruption | Breast Cancer Research
Turken O, NarIn Y, DemIrbas S, Onde ME, Sayan O, KandemIr EG, et al. Breast cancer in association…
Dysfunctional mitochondria shown to initiate the onset of Parkinson’s
For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson’s disease. But…
Innovative research reveals FGD3 as a key player in breast cancer cell death
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the…