Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Orange Cats Are Genetically Unlike Any Other Mammal and Now We Know Why
Credit: Pixabay. Chris Kaelin, a geneticist at Stanford Medicine, found himself thinking about cats. Not just any cats,…
Pioneering personalized medicine by deciphering depression’s complex biological web
In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Najaf Amin unveils transformative insights that…
Somatic mutation and selection at population scale
Cohort selection The TwinsUK study contains around 16,000 participants. From a preselection of 4,800 donors, we invited 1,796…
Refined DNA sequencing tool reveals hidden mutations behind aging and cancer
Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our…
“Junk DNA” Provides Surprising New Treatments for Hard-To-Treat Blood Cancers
Researchers at King’s College London have uncovered a surprising vulnerability in certain blood cancers by targeting a part…
Calcium-induced release identified as key driver of dangerous muscle disorders
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without…
Malaria-Transmitting Mosquito’s Genetic Diversity and Evolution Revealed
There are a variety of methods that have been established to curtail the spread of infectious disease, from…
Low dose of aspirin cuts recurrence risk in colorectal cancer with genetic mutation
A Swedish-led research team at Karolinska Institutet and Karolinska University Hospital has shown in a new randomized clinical…