Blood gene signals reveal Parkinson’s risk years before diagnosis
Blood-based DNA repair and stress-response signals reveal a brief molecular window preceding Parkinson’s diagnosis. Study: Longitudinal assessment of…
Distinct tau chemical signatures redefine diagnosis across neurodegenerative diseases
Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as “tauopathies”). New…
Olive oil type matters for cognition and gut health in older adults
A large cohort study suggests that not all olive oils are equal, with virgin olive oil showing favorable…
Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease
From protein misfolding to gut–brain signalling, emerging evidence suggests that everyday plastic exposure may intersect with key biological…
Experts issue strong call for overhaul of UK dementia prevention strategy
A national panel of experts has issued the strongest call yet for the Department of Health and Social…
How the brain protects itself from Alzheimer’s disease: study
High levels of calcium are toxic to cells and contribute to loss of neurons in Alzheimer’s disease. A…
Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer’s
Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the…
TRIMTECH Therapeutics appoints Dr Mike Hutton to Scientific Advisory Board
TRIMTECH Therapeutics, a biotech company creating novel, small molecule therapeutics that selectively degrade protein aggregates, to combat neurodegenerative…
Fruit flies illuminate the role of Alzheimer’s disease risk genes
Scientists have identified hundreds of genes that may increase the risk of developing Alzheimer’s disease but the roles…
Women with isolated REM sleep behavior disorder show lesser brain atrophy than men
A large international study involving nearly 700 participants reveals that women with a precursor condition to Parkinson’s disease…
Genetic variation in the glucagon-like peptide-1 receptor protein encoding region is associated with higher heart rate variability, but not with neurodegeneration of the brain, retina, and peripheral nerves: The Maastricht study | Cardiovascular Diabetology
Badrov MB, Mak S, Floras JS. Cardiovascular autonomic disturbances in heart failure with preserved ejection fraction. Can J…
Digital test plus blood biomarker boosts accuracy of Alzheimer’s diagnosis in primary care
By confirming cognitive impairment before ordering amyloid blood tests, this two-step approach cuts false positives, streamlines referrals, and…