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Browsing Tag

pH

72 posts
HHealth
Living in food deserts linked to higher stroke and death risk in atrial fibrillation patients
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Aneurysm with a cervical artery dissection may not increase risk of stroke later

  • January 29, 2026
People who developed a type of aneurysm with a cervical artery dissection (a tear in the inner lining…
HHealth
electronRx to launch pDx app for remote chronic respiratory disease management
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Emerging animal viruses may pose overlooked threats to future human outbreaks

  • January 29, 2026
Two emerging pathogens with animal origins – influenza D virus and canine coronavirus – have so far been…
HHealth
Living in food deserts linked to higher stroke and death risk in atrial fibrillation patients
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New 2026 guideline expands access to advanced acute ischemic stroke care

  • January 27, 2026
Expanded eligibility for advanced stroke therapies and new recommendations for diagnosing and treating stroke in children and adults are among…
SScience
Discovery of unexpected mechanism may help improve healing across muscle injuries
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Study shows DHPS enzyme controls macrophage maturation across multiple organs

  • January 22, 2026
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
HHealth
Using AI to enhance the design of nanoparticles for RNA therapies
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Weill Cornell Medicine receives ARPA-H award to advance lymphatic disease diagnosis

  • January 21, 2026
Weill Cornell Medicine has received a $5.2 million, initial two-year award from the Advanced Research Projects Agency for…
HHealth
Beautiful smiling little girl drinking a glass of water against the background of the kitchen.
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Groundwater chemistry may raise children’s lead exposure risk

  • January 20, 2026
A nationwide county-level study reveals how subtle differences in groundwater chemistry may influence pipe corrosion and children’s blood…
TTechnology
Rare case of pancreatic Hodgkin lymphoma is often misdiagnosed as pancreatic adenocarcinoma
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Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

  • January 17, 2026
Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and…
SScience
Electrical stimulation predicts recovery potential after acute nerve injuries
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Stimulating immune cells could offer new treatment for nerve injury pain

  • January 8, 2026
Researchers at The University of Texas MD Anderson Cancer Center have discovered that targeting a specific immune process…
EEnvironment
Researchers Say the Oceans Have Passed a Milestone for Acidification
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Researchers Say the Oceans Have Passed a Milestone for Acidification

  • January 5, 2026
  [By Anna Napolitano] The past 12 months have been worrying for researchers who study the chemistry of…
HHealth
New insights reveal persistent genome structure during cell division
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New insights into the global expansion of Candida auris

  • December 31, 2025
The fungal species Candida auris is spreading across the globe, and gaining in virulence, according to a new…
SScience
Polβ enzyme found to protect developing brain from harmful DNA mutations
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Engineered sensor reveals the brain’s hidden chemical conversations

  • December 24, 2025
Scientists have engineered a protein able to record the incoming chemical signals of brain cells (as opposed to…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
Ireland
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