Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
Cryo-EM provides real-time glimpse of cellular machinery reading DNA inside living organisms
All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the…
Salk scientists use DNA origami to track molecular movements
Scientists often describe life as a series of chemical reactions. Pallav Kosuri, PhD, describes life as movement. Chemical…
Oral drug candidate blocks transmission of measles-like disease in ferrets
A new oral antiviral drug candidate administered either before or after direct contact or airborne exposure to canine…
New study tracks early genetic changes in hepatitis E virus
Knowing how viruses change in the initial weeks of an infection can provide important information about their adaptability.…
New mechanism to enhance precision in cancer drug development
Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects…
Chromosome abnormalities may help cancer cells resist treatment and spread
A new study led by NYU Langone Health researchers found that cancer cells are better able to resist…
New method isolates true transcription factor targets in tuberculosis bacteria
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.…
Study reveals poxvirus’s unique DNA clamp for gene activation
A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study…
Engineered enzyme enables fast and accurate RNA synthesis
From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as…
New diagnostic framework addresses challenges of rapidly-mutating RNA viruses
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex…
Scientists uncover new mechanism initiating gene transcription
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular…