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Browsing Tag

Preclinical

15 posts
HHealth
Discovery of mitochondrial microprotein opens path to obesity and aging therapies
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Strong grip strength lowers risk of organ dysfunction in obesity

  • October 21, 2025
People with obesity who also have high muscle mass may be less likely to have obesity-related organ damage.…
HHealth
Lactylation drives tumor progression and immune evasion in triple negative breast cancer
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Fatty acids found to be a primary driver of triple-negative tumor growth

  • October 16, 2025
A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast…
SScience
Nanodroplet array revolutionizes search for new drugs
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UC Irvine develops human-like colon model for precision medicine

  • October 16, 2025
Researchers at the University of California, Irvine have developed a 3D human colon model integrated with bioelectronics to…
HHealth
New generation of CRISPR shows safer path to treating genetic diseases
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Highly targeted gene therapy could revolutionize treatment for cancers linked to herpesvirus

  • October 3, 2025
In a preclinical study, UC Davis Comprehensive Cancer Center scientists developed a highly targeted gene therapy that could…
GGenetics
Amino acid metabolism shapes the tumor immune microenvironment and therapy response
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Genetic modification enhances “living drugs” for blood cancers

  • September 25, 2025
CAR T cells are patient-derived, genetically engineered immune cells. They are “living drugs” and constitute a milestone in…
HHealth
Glucose-fructose mix found in sugary drinks fuels colorectal cancer metastasis
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Glucose-fructose mix found in sugary drinks fuels colorectal cancer metastasis

  • September 20, 2025
A new study from researchers at The University of Texas MD Anderson Cancer Center shows that the glucose-fructose…
HHealth
Study: Plasma Phosphorylated Tau 217 to Identify Preclinical Alzheimer Disease. Image Credit: Atthapon Raksthaput / Shutterstock
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Two-step blood and scan strategy delivers near-perfect accuracy for early Alzheimer signs

  • September 17, 2025
A simple blood test for p-tau217, when combined with confirmatory brain scans or CSF analysis, could transform early…
GGenetics
Study: Genetically modeled GLP1R and GIPR agonism reduce binge drinking and alcohol-associated phenotypes: a multi-ancestry drug-target Mendelian randomization study. Image Credit: Voyagerix / Shutterstock
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Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use

  • September 15, 2025
New genetic evidence suggests that targeting GIPR and GLP1R could reduce harmful drinking patterns while improving liver and…
HHealth
Depressive symptoms may interfere with learning to actively avoid unpleasant events
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Depressive symptoms may interfere with learning to actively avoid unpleasant events

  • September 2, 2025
Depression alters how people pursue rewards, but, conversely, whether depressive symptoms influence how people learn to avoid nonrewarding,…
HHealth
Effects of different honey types on the main molecular features of Alzheimer disease. Arrows’ design reflects the strength of the evidence. Abbreviations: AA = arachidonic acid; Aβ= amyloid beta;
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Can honey protect your brain? Study reviews its potential against Alzheimer’s

  • September 2, 2025
From chestnut to manuka, honey varieties demonstrate neuroprotective power in lab studies against Alzheimer’s disease, but scientists stress…
HHealth
Review: Polyphenols and Alzheimer
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How plant compounds could target Alzheimer’s disease from multiple angles

  • September 1, 2025
Scientists reveal how plant-based compounds may combat Alzheimer’s through multi-target actions, but poor bioavailability and the blood-brain barrier…
HHealth
Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors
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Certain dietary fats found to trigger hard-to-treat asthma in children

  • August 27, 2025
Researchers at Children’s Hospital of Philadelphia (CHOP) found that certain lipids, or fats, in obesity-causing foods also cause…
Ireland
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