Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Immune cell dysregulation and inflammatory mediators shape epilepsy risk
Background and objectives Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal…
Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally…
WHO reviews highlight limited long-term data on GLP-1 drug safety
Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies…
Diabetes remission possible with GLP-1 drugs, Italian study confirms
Real-world data from over 14,000 Italian adults reveal that GLP-1 receptor agonists can induce remission in type 2…
How COVID mRNA vaccines may make cancer treatments more effective
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
GLP-1 receptor agonists linked to altered patterns on FDG PET-CT scans
The growing use of GLP-1 receptor agonists may affect the interpretation of oncological FDG PET-CT scans, new research…
Paternal exercise enhances offspring endurance through sperm microRNAs
In a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen,…
Engineered CAR T cells show promise against solid tumors
Chimeric antigen receptor (CAR) T cell therapy, which uses a patient’s own immune cells to fight cancer, has…
Calcium-induced release identified as key driver of dangerous muscle disorders
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without…
Genetic modification enhances “living drugs” for blood cancers
CAR T cells are patient-derived, genetically engineered immune cells. They are “living drugs” and constitute a milestone in…