Distinct tau chemical signatures redefine diagnosis across neurodegenerative diseases
Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as “tauopathies”). New…
Virus shells use asymmetry to control RNA release and infection
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new…
Online reference library provides a more accurate picture of drug exposure
Doctors and researchers try to understand what medications a person has taken by asking patients directly or by…
Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease
A phase 2 trial suggests that a drug commonly used for constipation may help preserve kidney function in…
Chronic drinking weakens the blood-brain barrier through the gut
Scientists trace alcohol’s impact from the gut to the brain, uncovering microbial changes that weaken the blood-brain barrier,…
Two-step blood and scan strategy delivers near-perfect accuracy for early Alzheimer signs
A simple blood test for p-tau217, when combined with confirmatory brain scans or CSF analysis, could transform early…
New technique used to conduct real-time measurement of boron in live tumor cells
A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better…
Core sugars in breast milk fuel gut and brain health beyond 12 months
A comprehensive review reveals that six core breast milk sugars persist well beyond infancy, providing ongoing benefits for…
Compounds show significant inhibitory effects on α-glucosidase
Three of the compounds demonstrated significant inhibitory effects on α-glucosidase, a key enzyme in carbohydrate digestion. The findings…
Visualizing lipid transport inside living cells with fluorescence microscopy
To the point: New technique to image single lipids: Lipids are notoriously difficult to detect with light microscopy.…
New microfluidics-based workflow enables high-resolution lipid imaging in C. elegans
Understanding how fat molecules are distributed and function in living organisms is key to uncovering mechanisms of aging,…
Single-cell proteomic analysis uncovers hidden layers of blood cell formation
In the past decade there has been significant interest in studying the expression of our genetic code down…