Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…
Genomic study advances prioritization of variants in cancer diagnostics
Hiroshima University researchers have developed a practical framework to identify candidate pathogenic variants hidden among the large number…
FOXJ3 gene identified as the critical link between abnormal brain development and epilepsy
Researchers have discovered that mutations in the FOXJ3 gene act as a “master switch” failure, disrupting how the…
New clues reveal how gestational diabetes affects offspring
Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely…
Cancer hijacks embryonic gene editors to fuel growth
Cancer cells are known to reawaken embryonic genes to grow. A new study reveals the disease also hijacks…
Scientists uncover 53 genetic clues that shape math ability beyond IQ
An exciting new study reveals the hidden genetic architecture of quantitative ability, showing how brain wiring and signaling…
Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China
Cornelia de Lange syndrome (CdLS) is a rare genetic disorder with symptoms, including facial anomalies (such as fused…
Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors
A new study, led by researchers at Children’s Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA…